Lysosomal enzyme can bypass the blood-brain barrier and reach the CNS following intranasal administration (Q34261645)

1 August 2017

Lysosomal enzyme can bypass the blood-brain barrier and reach the CNS following intranasal administration (English)

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1 August 2017

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R Scott McIvor

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1 August 2017

Daniel A Wolf

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1 August 2017

Leah R Hanson

2

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1 August 2017

Elena L Aronovich

3

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1 August 2017

Zhenhong Nan

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1 August 2017

Walter C Low

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1 August 2017

William H Frey

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1 August 2017

10 February 2012

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Molecular Genetics and Metabolism

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1 August 2017

106

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131-134

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Transnasal delivery of methotrexate to brain tumors in rats: a new strategy for brain tumor chemotherapy

1 August 2017

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Intranasal delivery of cells to the brain.

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Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease.

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Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system

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Effect of intranasal administration of Semliki Forest virus recombinant particles expressing reporter and cytokine genes on the progression of experimental autoimmune encephalomyelitis.

7 January 2021

1 reference

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Intranasal administration of the growth-compromised HSV-2 vector DeltaRR prevents kainate-induced seizures and neuronal loss in rats and mice

7 January 2021

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Intranasal drug targeting of hypocretin-1 (orexin-A) to the central nervous system.

7 January 2021

1 reference

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Delivery of nerve growth factor to brain via intranasal administration and enhancement of brain uptake

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.02.006

Delivery of NGF to the brain: intranasal versus ocular administration in anti-NGF transgenic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.02.006

Intranasal administration of NAP, a neuroprotective peptide, decreases anxiety-like behavior in aging mice in the elevated plus maze.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.02.006

Intranasal delivery to the central nervous system: mechanisms and experimental considerations

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.02.006

Intranasal nerve growth factor enhances striatal neurogenesis in adult rats with focal cerebral ischemia

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https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.02.006

Activated microglia in cortex of mouse models of mucopolysaccharidoses I and IIIB

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Direct gene transfer to the CNS prevents emergence of neurologic disease in a murine model of mucopolysaccharidosis type I.

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Characterization of an immunodeficient mouse model of mucopolysaccharidosis type I suitable for preclinical testing of human stem cell and gene therapy

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Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system

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A dose-optimization trial of laronidase (Aldurazyme) in patients with mucopolysaccharidosis I

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Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII.

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Long-term and high-dose trials of enzyme replacement therapy in the canine model of mucopolysaccharidosis I.

7 January 2021

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Biodistribution and pharmacodynamics of recombinant human alpha-L-iduronidase (rhIDU) in mucopolysaccharidosis type I-affected cats following multiple intrathecal administrations

7 January 2021

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Intrathecal enzyme replacement therapy in a patient with mucopolysaccharidosis type I and symptomatic spinal cord compression

7 January 2021

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Intrathecal enzyme replacement therapy: successful treatment of brain disease via the cerebrospinal fluid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2012.02.006

10.1016/J.YMGME.2012.02.006

7 January 2021

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DOI

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1 August 2017

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