Polyclonal B cell activation in lupus-prone mice precedes and predicts the development of autoimmune disease (Q34261883)

1 August 2017

Polyclonal B cell activation in lupus-prone mice precedes and predicts the development of autoimmune disease (English)

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1 August 2017

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Klinman DM

1

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PubMed ID

2212009

1 August 2017

language of work or name

English

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publication date

1 October 1990

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Journal of Clinical Investigation

1 August 2017

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1 August 2017

86

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1 August 2017

4

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1 August 2017

1249-1254

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Enhancing effect of H-2-linked NZW gene(s) on the autoimmune traits of (NZB X NZW)F1 mice

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Genetic studies in NZB mice. V. Recombinant inbred lines demonstrate that separate genes control autoimmune phenotype

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Etiopathogenesis of Murine SLE1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Genetic studies in NZB mice. VI. Association of autoimmune traits in recombinant inbred lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Pathogenesis of the glomerulonephritis of NZB/W mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

The contribution of NZW genes to lupus-like disease in (NZB x NZW)F1 mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Autoantibody production is associated with polyclonal B cell activation in autoimmune mice which express the lpr or gld genes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Acquisition and maturation of expressed B cell repertoires in normal and autoimmune mice.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

CD5+ B lymphocytes, polyreactive antibodies and the human B-cell repertoire

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Shared idiotypes and restricted immunoglobulin variable region heavy chain genes characterize murine autoantibodies of various specificities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Changes in immunoglobulin class and subclass of anti-DNA antibodies with increasing age in N/ZBW F1 hybrid mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Three genes for lupus nephritis in NZB x NZW mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Synthesis of IgM by cells of NZB and SWR mice and their crosses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Genetic studies in NZB mice. I. Spontaneous autoantibody production

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Increased spontaneous activity of antibody-forming cells in the peripheral blood of patients with active sle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Immunological regulation of spontaneous antibodies to DNA and RNA. II. Sequential switch from IgM to IgG in NZB/NZW F1 mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Immunologic factors and clinical activity in systemic lupus erythematosus.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Systemic autoimmune disease arises from polyclonal B cell activation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Development of the autoimmune B cell repertoire in MRL-lpr/lpr mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=296855

Genetic studies of autoimmunity in New Zealand mice. IV. Contribution of NZB and NZW genes to the spontaneous occurrence of retroviral gp70 immune complexes in (NZB X NZW)F1 hybrid and the correlation to renal disease

28 October 2018

1 reference

12 December 2020

Subclass restriction of anti-Sm antibodies in MRL mice

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12 December 2020

In vivo and in vitro production of anti-histone antibodies in NZB/NZW mice

1 reference

12 December 2020

B lymphocyte lineage cells in newborn and very young NZB mice: evidence for regulatory disorders affecting B cell formation

1 reference

12 December 2020

Genetic regulation of the class conversion of dsDNA-specific antibodies in (NZB X NZW)F1 hybrid

1 reference

12 December 2020

Proliferation of anti-DNA-producing NZB B cells in a non-autoimmune environment

1 reference

12 December 2020

Detection of native and denatured DNA antibody forming cells by the enzyme-linked immunospot assay. A clinical study of (New Zealand black x New Zealand white)F1 mice

1 reference

12 December 2020

Isotype progression and clonality of anti-Sm autoantibodies in MRL/Mp-lpr/lpr mice

1 reference

12 December 2020

The role of clonal selection and somatic mutation in autoimmunity

1 reference

12 December 2020

Novel ELISA and ELISA-spot assays used to quantitate B cells and serum antibodies specific for T cell and bromelated mouse red blood cell autoantigens

1 reference

12 December 2020

Increased autoantibody production by NZB/NZW B cells in response to IL-5

1 reference

12 December 2020

Responses of B cells from autoimmune mice to IL-5

1 reference

12 December 2020

Regulation of B cell activation in autoimmune mice

1 reference

12 December 2020

Hyperreactivity of activated B cells to B cell growth factor in patients with systemic lupus erythematosus

1 reference

12 December 2020

Therapeutic studies in NZB/W mice. III. Relationship between renal status and efficacy of immunosuppressive drug therapy

1 reference

12 December 2020

Restricted subpopulations of DNA antibodies in kidneys of mice with systemic lupus. Comparison of antibodies in serum and renal eluates

1 reference

12 December 2020

Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus.

1 reference

12 December 2020

Analysis of NZB hyperdiploid spleen cells

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12 December 2020

Genetic studies of autoimmunity in New Zealand mice. III. Associations among anti-DNA antibodies, NTA, and renal disease in (NZB x NZW)F1 x NZW backcross mice

1 reference

12 December 2020

Correlation of serum IgG, IgM, and anti-native-DNA antibodies with renal and clinical indexes of activity in systemic lupus erythematosus

1 reference

12 December 2020

Independent segregation of NZB immune abnormalities in NZB x C58 recombinant inbred mice

1 reference

12 December 2020

A solid-phase immunoenzymatic technique for the enumeration of specific antibody-secreting cells

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI114831

1 reference

1 August 2017

1 reference

1 August 2017

1 reference

PubMed ID

2212009