MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme (Q34262423)

1 August 2017

title

MicroRNAs/TP53 feedback circuitry in glioblastoma multiforme (English)

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1 August 2017

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13

Carlo M Croce

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1 August 2017

Sung-Suk Suh

1

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1 August 2017

Ji Young Yoo

2

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1 August 2017

Gerard J Nuovo

3

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1 August 2017

Young-Jun Jeon

4

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1 August 2017

Seokho Kim

5

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1 August 2017

Tae Jin Lee

6

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1 August 2017

Taewan Kim

7

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1 August 2017

Arianna Bakàcs

8

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1 August 2017

Hansjuerg Alder

9

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1 August 2017

Balveen Kaur

10

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1 August 2017

Rami I Aqeilan

11

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1 August 2017

Flavia Pichiorri

12

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1 August 2017

language of work or name

English

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publication date

19 March 2012

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

109

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1 August 2017

issue

14

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1 August 2017

page(s)

5316-5321

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Activation of p53 by nutlin-3a induces apoptosis and cellular senescence in human glioblastoma multiforme

1 August 2017

cites work

1 reference

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Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia

6 July 2018

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Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development

6 July 2018

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Negative regulation of the tumor suppressor p53 gene by microRNAs.

6 July 2018

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E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis

6 July 2018

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Small-molecule inhibitors of MDM2 as new anticancer therapeutics

6 July 2018

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6 July 2018

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p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation.

6 July 2018

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6 July 2018

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E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer

6 July 2018

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Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

6 July 2018

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Global and local architecture of the mammalian microRNA-transcription factor regulatory network.

6 July 2018

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

6 July 2018

1 reference

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Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors

6 July 2018

1 reference

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MicroRNA signatures in human cancers

6 July 2018

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mTOR and cancer: insights into a complex relationship

6 July 2018

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The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

c-Myc-regulated microRNAs modulate E2F1 expression

6 July 2018

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A microRNA polycistron as a potential human oncogene

6 July 2018

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The coordinate regulation of the p53 and mTOR pathways in cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

RAS is regulated by the let-7 microRNA family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

p53-dependent down-regulation of telomerase is mediated by p21waf1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Myc pathways provoking cell suicide and cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

E2F1 and c-Myc in cell growth and death.

6 July 2018

1 reference

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E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

6 July 2018

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Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Inactivation of Myc-induced p53-dependent apoptosis in human tumors.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

MDM2 and p53 expression in gliomas: a multivariate survival analysis including proliferation markers and epidermal growth factor receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Mutations in the p53 gene occur in diverse human tumour types

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Induction of apoptosis in fibroblasts by c-myc protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

Analysis of glioma cell lines for amplification and overexpression of MDM2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325690

The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target.

28 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1202465109

21 January 2018

Identifiers

DOI

10.1073/PNAS.1202465109

1 reference

release_ysfy5abflzf2jiajgdyqamay6q

1 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ysfy5abflzf2jiajgdyqamay6q

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3325690

1 reference

1 August 2017

1 reference