Does sufficient evidence exist to support a causal association between vitamin D status and cardiovascular disease risk? An assessment using Hill's criteria for causality (Q34263443)

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English	Does sufficient evidence exist to support a causal association between vitamin D status and cardiovascular disease risk? An assessment using Hill's criteria for causality	scientific article

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

5 references

14 March 2019

19 March 2019

17 June 2019

13 November 2019

14 November 2020

Does sufficient evidence exist to support a causal association between vitamin D status and cardiovascular disease risk? An assessment using Hill's criteria for causality (English)

1 reference

Europe PubMed Central

1 August 2017

0 references

cardiovascular disease

5 references

14 March 2019

19 March 2019

17 June 2019

13 November 2019

14 November 2020

polycyclic compound

1 reference

13 November 2019

vitamin D deficiency

1 reference

14 November 2020

author name string

Patricia G Weyland

1

1 reference

Europe PubMed Central

1 August 2017

William B Grant

2

1 reference

Europe PubMed Central

1 August 2017

Jill Howie-Esquivel

3

1 reference

Europe PubMed Central

1 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

2 September 2014

6 references

Europe PubMed Central

1 August 2017

14 March 2019

19 March 2019

17 June 2019

13 November 2019

14 November 2020

6 references

Europe PubMed Central

1 August 2017

14 March 2019

19 March 2019

17 June 2019

13 November 2019

14 November 2020

6

1 reference

Europe PubMed Central

1 August 2017

9

1 reference

Europe PubMed Central

1 August 2017

3403-3430

1 reference

Europe PubMed Central

1 August 2017

copyright license

Creative Commons Attribution

5 references

14 March 2019

19 March 2019

17 June 2019

13 November 2019

14 November 2020

copyright status

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on focus list of Wikimedia project

0 references

Vitamin d status in central europe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

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The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis.

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Calcium/vitamin D supplementation, serum 25-hydroxyvitamin D concentrations, and cholesterol profiles in the Women's Health Initiative calcium/vitamin D randomized trial

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Guidelines for optimizing design and analysis of clinical studies of nutrient effects

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Vitamin D is a regulator of endothelial nitric oxide synthase and arterial stiffness in mice

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The Inverse Relationship between 25-Hydroxyvitamin D and Cancer Survival: Discussion of Causation.

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25(OH) vitamin D suppresses macrophage adhesion and migration by downregulation of ER stress and scavenger receptor A1 in type 2 diabetes

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Roles of cardiovascular risk factors in endothelial nitric oxide synthase regulation: an update

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Molecular link between vitamin D and cancer prevention

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6 July 2018

Vitamin D supplementation in patients with diabetes mellitus type 2 on different therapeutic regimens: a one-year prospective study

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6 July 2018

Racial differences in the association of serum 25-hydroxyvitamin D concentration with coronary heart disease events

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6 July 2018

Vitamins - wrong approaches

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6 July 2018

Blood 25-hydroxy vitamin D levels and incident type 2 diabetes: a meta-analysis of prospective studies

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6 July 2018

Supplementation with High Doses of Vitamin D to Subjects without Vitamin D Deficiency May Have Negative Effects: Pooled Data from Four Intervention Trials in Tromsø.

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6 July 2018

Effect of vitamin D supplementation on blood pressure in blacks

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6 July 2018

The effect of vitamin D on insulin resistance in patients with type 2 diabetes

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6 July 2018

Decreased serum concentrations of 25-hydroxycholecalciferol are associated with increased risk of progression to impaired fasting glucose and diabetes

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6 July 2018

Plasma vitamin D and parathormone are associated with obesity and atherogenic dyslipidemia: a cross-sectional study

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6 July 2018

Circulating 25-Hydroxy-Vitamin D and Risk of Cardiovascular Disease: A Meta-Analysis of Prospective Studies

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6 July 2018

Is vitamin D status relevant to metabolic syndrome?

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6 July 2018

Does the evidence for an inverse relationship between serum vitamin D status and breast cancer risk satisfy the Hill criteria?

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6 July 2018

Why randomized controlled trials of calcium and vitamin D sometimes fail

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6 July 2018

The role of vitamin D in cardiovascular disease: from present evidence to future perspectives

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6 July 2018

Vitamin D3 supplementation has no effect on conventional cardiovascular risk factors: a parallel-group, double-blind, placebo-controlled RCT.

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6 July 2018

The relationship of vitamin D with non-traditional risk factors for cardiovascular disease in subjects with metabolic syndrome.

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6 July 2018

Arterial stiffness and vitamin D levels: the Baltimore longitudinal study of aging

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6 July 2018

Vitamin D intake is inversely related to risk of developing metabolic syndrome in African American and white men and women over 20 y: the Coronary Artery Risk Development in Young Adults study.

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6 July 2018

A prospective randomized controlled trial of the effects of vitamin D supplementation on cardiovascular disease risk

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6 July 2018

Effect of vitamin D supplementation on glycaemic control and insulin resistance: a systematic review and meta-analysis.

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6 July 2018

Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited.

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6 July 2018

25-Hydroxyvitamin D deficiency is associated with fatal stroke among whites but not blacks: The NHANES-III linked mortality files.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

6 July 2018

Role of vitamin d supplementation in hypertension

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6 July 2018

Vitamin D deficiency and mortality risk in the general population: a meta-analysis of prospective cohort studies

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6 July 2018

Vitamin D, insulin secretion, sensitivity, and lipids: results from a case-control study and a randomized controlled trial using hyperglycemic clamp technique

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6 July 2018

Serum 25-hydroxyvitamin D and change in estimated glomerular filtration rate

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6 July 2018

An estimate of the global reduction in mortality rates through doubling vitamin D levels

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6 July 2018

26th Hohenheim Consensus Conference, September 11, 2010 Scientific substantiation of health claims: evidence-based nutrition

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Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline

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6 July 2018

Are Hill's criteria for causality satisfied for vitamin D and periodontal disease?

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6 July 2018

The effect of atmospheric thermal conditions and urban thermal pollution on all-cause and cardiovascular mortality in Bangladesh

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6 July 2018

Prediabetes and prehypertension in healthy adults are associated with low vitamin D levels

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6 July 2018

Vitamin D(3) is more potent than vitamin D(2) in humans

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6 July 2018

Assessment of evidence for a protective role of vitamin D in multiple sclerosis

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6 July 2018

In defense of the sun: An estimate of changes in mortality rates in the United States if mean serum 25-hydroxyvitamin D levels were raised to 45 ng/mL by solar ultraviolet-B irradiance

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How strong is the evidence that solar ultraviolet B and vitamin D reduce the risk of cancer?: An examination using Hill's criteria for causality

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Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin D deficient - a randomised, placebo-controlled trial

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6 July 2018

1,25(OH)2 vitamin d inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus

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6 July 2018

25-hydroxyvitamin D levels inversely associate with risk for developing coronary artery calcification

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6 July 2018

Effects of vitamin D supplementation in atorvastatin-treated patients: a new drug interaction with an unexpected consequence

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6 July 2018

Baseline serum 25-hydroxy vitamin d is predictive of future glycemic status and insulin resistance: the Medical Research Council Ely Prospective Study 1990-2000

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6 July 2018

25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study

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6 July 2018

Vitamin D deficiency and risk of cardiovascular disease

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6 July 2018

Vitamin D deficiency

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6 July 2018

Plasma 25-hydroxyvitamin D levels and risk of incident hypertension

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6 July 2018

Risk assessment for vitamin D

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6 July 2018

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28 October 2018

What is the optimal vitamin D status for health?

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6 July 2018

Vitamin D and African Americans

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6 July 2018

Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older U.S. women

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6 July 2018

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Overview of general physiologic features and functions of vitamin D.

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6 July 2018

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6 July 2018

Using the coronary artery calcium score to predict coronary heart disease events: a systematic review and meta-analysis

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6 July 2018

The Environment and Disease: Association or Causation?

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6 July 2018

Causal criteria in nutritional epidemiology

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6 July 2018

Seasonality of Cardiovascular Disease Mortality and the Possible Protective Effect of Ultra-violet Radiation

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6 July 2018

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21 January 2018

Aortic stiffness and vitamin D are independent markers of aortic calcification in patients with peripheral arterial disease and in healthy subjects

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21 January 2018

The relationship of vitamin D status to cardiovascular risk factors and amputation risk in veterans with peripheral arterial disease

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21 January 2018

Conduit vessel stiffness in British south Asians of Indian descent relates to 25-hydroxyvitamin D status.

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21 January 2018

Low vitamin D levels are related to left ventricular concentric remodelling in men of different ethnic groups with varying cardiovascular risk

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21 January 2018

Relation between the Framingham Risk Score, coronary calcium, and incident coronary heart disease among low-risk men.

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21 January 2018

Low plasma 25-hydroxyvitamin D and risk of tobacco-related cancer

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21 January 2018

Ultraviolet B and blood pressure

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Independent associations of serum concentrations of 25-hydroxyvitamin D and parathyroid hormone with blood pressure among US adults

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21 January 2018

High serum 25-hydroxyvitamin D concentrations are associated with a favorable serum lipid profile

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21 January 2018

Oral administration of an active form of vitamin D3 (calcitriol) decreases atherosclerosis in mice by inducing regulatory T cells and immature dendritic cells with tolerogenic functions.

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21 January 2018

Optimal vitamin D status: a critical analysis on the basis of evidence-based medicine

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21 January 2018

Relation of severe deficiency of vitamin D to cardiovascular mortality during acute coronary syndromes

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21 January 2018

Serum 25-hydroxyvitamin D concentration, established and emerging cardiovascular risk factors and risk of myocardial infarction before the age of 60 years.

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21 January 2018

25-Hydroxyvitamin D deficiency is independently associated with cardiovascular disease in the Third National Health and Nutrition Examination Survey

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21 January 2018

Cholecalciferol administration blunts the systemic renin-angiotensin system in essential hypertensives with hypovitaminosis D.

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21 January 2018

Effect of high doses of vitamin D on arterial properties, adiponectin, leptin and glucose homeostasis in type 2 diabetic patients

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21 January 2018

Vitamin D has a greater impact on cancer mortality rates than on cancer incidence rates

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21 January 2018

Low serum 25-hydroxyvitamin D is associated with increased risk of the development of the metabolic syndrome at five years: results from a national, population-based prospective study (The Australian Diabetes, Obesity and Lifestyle Study: AusDiab).

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21 January 2018

Prevalence of diabetes and impaired glucose metabolism in younger 'at risk' UK adults: insights from the STAND programme of research.

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21 January 2018

Randomized controlled trial of vitamin D supplement on endothelial function in patients with type 2 diabetes.

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21 January 2018

Predisease conditions and serum vitamin D levels in healthy Mexican American adults.

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21 January 2018

VDR-mediated gene expression patterns in resting human coronary artery smooth muscle cells.

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21 January 2018

Diverse associations of 25-hydroxyvitamin D and 1,25-dihydroxy-vitamin D with dyslipidaemias

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21 January 2018

Vitamin D receptor activation down-regulates the small heterodimer partner and increases CYP7A1 to lower cholesterol.

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21 January 2018

Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial

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21 January 2018

Primary malignancy in patients with nonmelanoma skin cancer-letter

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28 October 2018

Vitamin D status and oxidative stress markers in the elderly with impaired fasting glucose and type 2 diabetes mellitus.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

28 October 2018

Effects of vitamin D on cardiovascular disease risk factors in polycystic ovary syndrome women with vitamin D deficiency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

28 October 2018

Plasma vitamin D levels and risk of metabolic syndrome in Canadians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

28 October 2018

Vitamin D status: United States, 2001-2006.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

28 October 2018

Vitamin D supplement doses and serum 25-hydroxyvitamin D in the range associated with cancer prevention.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

28 October 2018

Mortality among teenagers aged 12-19 years: United States, 1999-2006.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

28 October 2018

Serum 25-Hydroxyvitamin D Concentration in Subclinical Carotid Atherosclerosis

1 reference

https://api.crossref.org/works/10.3390%2FNU6093403

21 January 2018

The association between low 25-hydroxyvitamin D and increased aortic stiffness

1 reference

https://api.crossref.org/works/10.3390%2FNU6093403

21 January 2018

Association of Parathyroid Hormone and 25-OH-Vitamin D Levels with Arterial Stiffness in Postmenopausal Women with Vitamin D Insufficiency

1 reference

https://api.crossref.org/works/10.3390%2FNU6093403

21 January 2018

Seasonal variation of blood pressure and its relationship to ambient temperature in an elderly population

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4179168

28 October 2018

https://api.crossref.org/works/10.3390%2FNU6093403

21 January 2018

Effect of Cholecalciferol Supplementation During Winter Months in Patients With Hypertension: A Randomized, Placebo-Controlled Trial

1 reference

https://api.crossref.org/works/10.3390%2FNU6093403

21 January 2018

Effects of a 1-year supplementation with cholecalciferol on interleukin-6, tumor necrosis factor-alpha and insulin resistance in overweight and obese subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D deficiency and supplementation and relation to cardiovascular health

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of the reliability and validity of biochemical measures

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Explaining the Decrease in U.S. Deaths from Coronary Disease, 1980–2000

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D deficiency may be an independent risk factor for arterial disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of the combined left ventricular systolic and renal dysfunction on one-year outcomes after primary percutaneous coronary intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of Vitamin D Deficiency to Cardiovascular Risk Factors, Disease Status, and Incident Events in a General Healthcare Population

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using findings from observational studies to guide vitamin D randomized controlled trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Whole body UVA irradiation lowers systemic blood pressure by release of nitric oxide from intracutaneous photolabile nitric oxide derivates

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D in Relation to Myocardial Structure and Function after Eight Years of Follow-Up: The Hoorn Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of simvastatin/ezetimibe 10/10 mg versus simvastatin 40 mg on serum vitamin D levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin D and the cardiovascular system

1 reference

https://pubmed.ncbi.nlm.nih.gov/25184368

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/NU6093403

0 references

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

ResearchGate publication ID

0 references

Sitelinks

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