Roles of the NKG2D immunoreceptor and its ligands (Q34267094)

1 August 2017

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title

Roles of the NKG2D immunoreceptor and its ligands (English)

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1 August 2017

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17 March 2024

1

David H Raulet

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1 August 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14523385

17 March 2024

publication date

1 October 2003

1 reference

full work available at URL

1 August 2017

http://www.nature.com/articles/nri1199.pdf

file format

Portable Document Format

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http://www.nature.com/articles/nri1199

17 March 2024

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Nature Reviews Immunology

17 March 2024

published in

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1 August 2017

3

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1 August 2017

781-790

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1 August 2017

10

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DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells

1 August 2017

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Functions of nonclassical MHC and non-MHC-encoded class I molecules.

31 March 2020

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A 2-Mb YAC contig and physical map of the natural killer gene complex on mouse chromosome 6.

31 March 2020

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A multigene family on human chromosome 12 encodes natural killer-cell lectins

31 March 2020

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The role of the NKG2D immunoreceptor in immune cell activation and natural killing

31 March 2020

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Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages.

31 March 2020

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UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells

31 March 2020

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Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

31 March 2020

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Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells

31 March 2020

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NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment

31 March 2020

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Role of NKG2D in tumor cell lysis mediated by human NK cells: cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin

31 March 2020

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Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis

31 March 2020

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A family of MHC class I-like genes located in the vicinity of the mouse leukocyte receptor complex

31 March 2020

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Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice

31 March 2020

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Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: one of the early inducible clones encodes a novel protein sharing several highly homologous regions with a Drosophila polyhomeotic protein

31 March 2020

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Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain

31 March 2020

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Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules

31 March 2020

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Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.

31 March 2020

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A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity

31 March 2020

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ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

31 March 2020

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A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3

31 March 2020

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Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family

31 March 2020

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A novel secreted tumor antigen with a glycosylphosphatidylinositol-anchored structure ubiquitously expressed in human cancers

31 March 2020

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ULBP4 is a novel ligand for human NKG2D

31 March 2020

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A second lineage of mammalian major histocompatibility complex class I genes

31 March 2020

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Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium

31 March 2020

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Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA

31 March 2020

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Molecular Competition for NKG2D

31 March 2020

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Ligands for murine NKG2D display heterogeneous binding behavior

31 March 2020

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Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand

31 March 2020

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Conformational plasticity revealed by the cocrystal structure of NKG2D and its class I MHC-like ligand ULBP3

31 March 2020

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Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D

31 March 2020

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Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A

31 March 2020

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Symmetry Recognizing Asymmetry

31 March 2020

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Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB

31 March 2020

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Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid

31 March 2020

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Critical role of MHC class I-related chain A and B expression on IFN-alpha-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection

31 March 2020

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Regulation of cutaneous malignancy by gammadelta T cells

31 March 2020

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Strategies for target cell recognition by natural killer cells

31 March 2020

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Selective intracellular retention of virally induced NKG2D ligands by the human cytomegalovirus UL16 glycoprotein

31 March 2020

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Binding of Escherichia coli adhesin AfaE to CD55 triggers cell-surface expression of the MHC class I-related molecule MICA

31 March 2020

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MICA engagement by human Vgamma2Vdelta2 T cells enhances their antigen-dependent effector function

31 March 2020

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NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules

31 March 2020

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Innate immune recognition

31 March 2020

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Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.

31 March 2020

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ULBP1, 2, 3: novel MHC class I-related molecules that bind to human cytomegalovirus glycoprotein UL16, activate NK cells

31 March 2020

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NKG2D-DAP10 triggers human NK cell–mediated killing via a Syk-independent regulatory pathway

31 March 2020

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Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists

31 March 2020

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Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity

31 March 2020

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Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells

31 March 2020

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Implication of gammadelta T cells in the human immune response to cytomegalovirus

31 March 2020

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An activating immunoreceptor complex formed by NKG2D and DAP10

31 March 2020

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Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D

31 March 2020

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NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation

31 March 2020

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Recruitment and activation of natural killer (NK) cells in vivo determined by the target cell phenotype. An adaptive component of NK cell-mediated responses

31 March 2020

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Cancer immunoediting: from immunosurveillance to tumor escape

31 March 2020

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NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases.

31 March 2020

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DAP10 and DAP12 form distinct, but functionally cooperative, receptor complexes in natural killer cells

31 March 2020

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T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gamma delta T cells

31 March 2020

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Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo

31 March 2020

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Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

31 March 2020

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Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia

31 March 2020

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Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin

31 March 2020

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MCMV glycoprotein gp40 confers virus resistance to CD8+ T cells and NK cells in vivo.

31 March 2020

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Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein

31 March 2020

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Human cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against natural killer cell cytotoxicity

31 March 2020

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Expression of the UL16 glycoprotein of Human Cytomegalovirus protects the virus-infected cell from attack by natural killer cells

31 March 2020

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Impairment of NK cell function by NKG2D modulation in NOD mice

31 March 2020

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Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

31 March 2020

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Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

31 March 2020

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The Journal of Molecular and Cellular Immunology

31 March 2020

1

4

295

JP Houchins

1990

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17 March 2024

41

62

6178

D Pende

2002

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17 March 2024

Identifiers

DOI

10.1038/NRI1199

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1 August 2017

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