The mechanism of lithium action: state of the art, ten years later (Q34268500)

1 August 2017

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title

The mechanism of lithium action: state of the art, ten years later (English)

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1 August 2017

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3

Belmaker RH

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1 August 2017

2

Agam G

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1 August 2017

Shaldubina A

1

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1 August 2017

1 May 2001

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Progress in Neuro-Psychopharmacology & Biological Psychiatry

1 August 2017

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1 August 2017

25

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1 August 2017

4

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1 August 2017

855-866

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Reduced Brain Inositol in Lithium-treated Rats

1 August 2017

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

How does lithium work on manic depression? Clinical and psychological correlates of the inositol theory

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Lithium research: state of the art.

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Epi-inositol and inositol depletion: two new treatment approaches in affective disorder.

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Bcl-2 promotes regeneration of severed axons in mammalian CNS

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Inhibition of glycogen synthase kinase 3beta activity regulates proliferation of cultured cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Cellular mechanisms of wingless/Wnt signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Lithium enhances accumulation of [3H]inositol radioactivity and mass of second messenger inositol 1,4,5-trisphosphate in monkey cerebral cortex slices.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Lithium stimulates glutamate "release" and inositol 1,4,5-trisphosphate accumulation via activation of the N-methyl-D-aspartate receptor in monkey and mouse cerebral cortex slices

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

A molecular and cellular theory of depression

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Increased tonic activation of rat forebrain 5-HT(1A) receptors by lithium addition to antidepressant treatments.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Activation of the Wnt signaling pathway: a molecular mechanism for lithium action.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Lithium reduces the accumulation of inositol polyphosphate second messengers following cholinergic stimulation of cerebral cortex slices

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

A molecular mechanism for the effect of lithium on development

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https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Intracerebroventricular myo-inositol antagonizes lithium-induced suppression of rearing behaviour in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Li+ increases accumulation of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate in cholinergically stimulated brain cortex slices in guinea pig, mouse and rat. The increases require inositol supplementation in mouse and rat but not

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3'-phosphoadenosine 5'-phosphate phosphatase and inositol-polyphosphate 1-phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Lithium at 50: have the neuroprotective effects of this unique cation been overlooked?

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

5-HT1B receptors: a novel target for lithium. Possible involvement in mood disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Evidence of the activity of lithium on 5-HT1B receptors in the mouse forced swimming test: comparison with carbamazepine and sodium valproate

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

A novel target of lithium therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0278-5846%2801%2900154-3

7 January 2021

10.1016/S0278-5846(01)00154-3

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11383981