A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H. (Q34268755)

1 August 2017

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title

A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H. (English)

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1 August 2017

3

Chattopadhyaya J

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1 August 2017

Zamaratski E

1

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PubMed ID

11384757

1 August 2017

Pradeepkumar PI

series ordinal

2

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1 August 2017

1 May 2001

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1 August 2017

Journal of Proteomics

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1 August 2017

48

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1 August 2017

3

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1 August 2017

189-208

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The Transmission of the Electronic Character of Guanin-9-yl Drives the Sugar-Phosphate Backbone Torsions in Guanosine 3′,5′-Bisphosphate

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Crystal structure of 2'-O-Me(CGCGCG)2, an RNA duplex at 1.30 A resolution. Hydration pattern of 2'-O-methylated RNA

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Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides

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Synthesis of alkylating oligonucleotide derivatives containing cholesterol or phenazinium residues at their 3'-terminus and their interaction with DNA within mammalian cells

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Effects of modulation of RNase H production on the recovery of DNA synthesis following UV-irradiation in Escherichia coli.

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Enzymatic amplification of translation inhibition of rabbit beta-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents

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Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides

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Cloning, expression, and mapping of ribonucleases H of human and mouse related to bacterial RNase HI

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Molecular mechanisms of action of antisense drugs

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Multiple mechanisms for initiation of ColE1 DNA replication: DNA synthesis in the presence and absence of ribonuclease H

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Melting of a DNA hairpin without hyperchromism

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7 January 2021

A cytosine analog that confers enhanced potency to antisense oligonucleotides

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Cloning of the cDNA encoding the large subunit of human RNase HI, a homologue of the prokaryotic RNase HII

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7 January 2021

RNase H cleavage of RNA hybridized to oligonucleotides containing methylphosphonate, phosphorothioate and phosphodiester bonds

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alpha-DNA. VI: Comparative study of alpha- and beta-anomeric oligodeoxyribonucleotides in hybridization to mRNA and in cell free translation inhibition

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Antisense effects of cholesterol-oligodeoxynucleotide conjugates associated with poly(alkylcyanoacrylate) nanoparticles

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Oligonucleotide N3'-->P5' phosphoramidates as potential therapeutic agents

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Antisense gene inhibition by C-5-substituted deoxyuridine-containing oligodeoxynucleotides

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Ribonuclease H. An Enzyme Degrading the RNA Moiety of DNA-RNA Hybrids

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1′,5′-Anhydrohexitol Oligonucleotides: Hybridisation and Strand Displacement with Oligoribonucleotides, Interaction with RNase H and HIV Reverse Transcriptase

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Conformationally restricted carbohydrate-modified nucleic acids and antisense technology

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Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries

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7 January 2021

Absence of a direct role for RNase HI in initiation of DNA replication at the oriC site on the Escherichia coli chromosome

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7 January 2021

RNase H-defective mutants of Escherichia coli: a possible discriminatory role of RNase H in initiation of DNA replication

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7 January 2021

Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H

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7 January 2021

Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H

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7 January 2021

Recognition of 2'-hydroxyl groups by Escherichia coli ribonuclease HI

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7 January 2021

Kinetic analysis of Escherichia coli ribonuclease HI using oligomeric DNA/RNA substrates suggests an alternative mechanism for the interaction between the enzyme and the substrate.

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7 January 2021

Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI

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Three-dimensional structure of ribonuclease H from E. coli

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7 January 2021

Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution

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Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

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Function of ribonuclease H in initiation of DNA replication in Escherichia coli K-12.

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LNA (Locked Nucleic Acid): An RNA Mimic Forming Exceedingly Stable LNA:LNA Duplexes

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7 January 2021

Relative thermodynamic stability of DNA, RNA, and DNA:RNA hybrid duplexes: relationship with base composition and structure.

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RNase H1 can catalyze RNA/DNA hybrid formation and cleavage with stable hairpin or duplex DNA oligomers

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7 January 2021

Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids

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7 January 2021

The influence of antisense oligonucleotide-induced RNA structure on Escherichia coli RNase H1 activity

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How much hydration is necessary for the stabilisation of DNA-duplex?

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Base-pair exchange kinetics of the imino and amino protons of the 3'-phenazinium tethered DNA-RNA duplex, r(5'GAUUGAA3'):d(5'TCAATC3'-Pzn), and their comparison with those of B-DNA duplex

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Poor hydration enhances the activation energy of the exchange rate of the base-paired imino protons with water at the core part of the DNA duplex

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The residence time of the bound water in the hydrophobic minor groove of the carbocyclic-nucleoside analogs of Dickerson-Drew dodecamers

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2'-carbohydrate modifications in antisense oligonucleotide therapy: importance of conformation, configuration and conjugation

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Nucleosides with a twist. Can fixed forms of sugar ring pucker influence biological activity in nucleosides and oligonucleotides?

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7 January 2021

Selecting effective antisense reagents on combinatorial oligonucleotide arrays

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Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA

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The use of single-stranded DNA and RNase H to promote quantitative 'hybrid arrest of translation' of mRNA/DNA hybrids in reticulocyte lysate cell-free translations

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Oligonucleotide Mimics for Antisense Therapeutics: Solution Phase and Automated Solid-Support Synthesis of MMI Linked Oligomers

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7 January 2021

How does RNase H recognize a DNA.RNA hybrid?

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7 January 2021

Solution structure of an RNA.2'-O-methylated RNA hybrid duplex containing an RNA.DNA hybrid segment at the center

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7 January 2021

Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA.RNA hybrid duplexes.

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7 January 2021

Binding of nucleic acids to E. coli RNase HI observed by NMR and CD spectroscopy

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7 January 2021

RNase H confers specificity in the dnaA-dependent initiation of replication at the unique origin of the Escherichia coli chromosome in vivo and in vitro

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A theoretical approach to select effective antisense oligodeoxyribonucleotides at high statistical probability

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Solution structure of RNA duplexes containing alternating CG base pairs: NMR study of r(CGCGCG)2 and 2'-O-Me(CGCGCG)2 under low salt conditions

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Boranophosphates support the RNase H cleavage of polyribonucleotides

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Interaction of cholesterol-conjugated alkylating oligonucleotide derivatives with cellular biopolymers

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7 January 2021

The DNA strand in DNA.RNA hybrid duplexes is neither B-form nor A-form in solution

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Antisense oligodeoxynucleotides: synthesis, biophysical and biological evaluation of oligodeoxynucleotides containing modified pyrimidines

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Rapid determination and quantitation of the accessibility to native RNAs by antisense oligodeoxynucleotides in murine cell extracts

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Rational selection of antisense oligonucleotide sequences

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7 January 2021

Studies of the interactions between Escherichia coli ribonuclease HI and its substrate

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Role of the Mg2+ ion in the Escherichia coli ribonuclease HI reaction

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Effects of 5-(N-aminohexyl)carbamoyl-2'-deoxyuridine on endonuclease stability and the ability of oligodeoxynucleotide to activate RNase H.

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7 January 2021

Coaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA folding

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Biophysical and biochemical properties of oligodeoxy-nucleotides containing 4'-C- and 5'-C-substituted thymidines

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Cyclohexene Nucleic Acids (CeNA): Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA

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Ribonucleases H of retroviral and cellular origin

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Molecular cloning and expression of cDNA for human RNase H.

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7 January 2021

Structure of ribonuclease H phased at 2 A resolution by MAD analysis of the selenomethionyl protein

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Stereo-enriched phosphorothioate oligodeoxynucleotides: synthesis, biophysical and biological properties

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Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11384757