Tibolone: a steroid with a tissue-specific mode of action (Q34268905)

1 August 2017

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title

Tibolone: a steroid with a tissue-specific mode of action (English)

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1 August 2017

Kloosterboer HJ

1

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1 August 2017

1 January 2001

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The Journal of Steroid Biochemistry and Molecular Biology

1 August 2017

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1 August 2017

76

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1 August 2017

1-5

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1 August 2017

231-238

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Pharmacological studies with (7 alpha,17 alpha)-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one (Org OD 14)

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

1 reference

7 January 2021

Nuclear receptor coregulators: cellular and molecular biology

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https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: analysis of interspecies variability and comparison with metabolism in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Enterohepatic Cycling and Pharmacokinetics of Oestradiol in Postmenopausal Women

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Bioequivalence assessment of three different estradiol formulations in postmenopausal women in an open, randomized, single-dose, 3-way cross-over study.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Pharmacology and pharmacokinetics of estrogens

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https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Different patterns of metabolism determine the relative anabolic activity of 19-norandrogens

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Human endometrial 3 beta-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic/progestagenic activity ratios of a steroidal drug (Org OD 14)

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Hormonal properties of norethisterone, 7alpha-methyl-norethisterone and their derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

The response in spinal bone mass to tibolone treatment is related to bone turnover in elderly women.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Effects of two doses of tibolone on trabecular and cortical bone loss in early postmenopausal women: a two-year randomized, placebo-controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

An assessment of hormone replacement therapy to prevent postmenopausal osteoporosis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Alendronate treatment for osteoporosis: a review of the clinical evidence.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Tibolone, a steroid with a tissue-specific hormonal profile, completely prevents ovariectomy-induced bone loss in sexually mature rats

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

1 reference

7 January 2021

The effects of tibolone

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https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

A primate model of human postmenopausal hot flushes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Effects of Org OD 14 on pituitary and peripheral beta-endorphin in castrated rats and post-menopausal women.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

The use of androgens in menopause

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https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

A key enzyme in the biosynthesis of neurosteroids, 3β-hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase (3β-HSD), is expressed in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

3 beta-hydroxysteroid dehydrogenase activity in tissues of the human fetus determined with 5 alpha-androstane-3 beta,17 beta-diol and dehydroepiandrosterone as substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Organon OD 14 (tibolone) and menopausal dynamic hormone profiles

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

In vitro evaluation of estrogenic, estrogen antagonistic and progestagenic effects of a steroidal drug (Org OD-14) and its metabolites on human endometrium

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Effects of progestagens and Org OD14 in in vitro and in vivo tumor models

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Mammographic density in postmenopausal women treated with tibolone, estriol or conventional hormone replacement therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Effects of post-menopausal oestrogen-progestogen replacement therapy on serum lipids and lipoproteins: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Lowered HDL cholesterol and incidence of ischaemic heart disease

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Effects of tibolone and continuous combined hormone replacement therapy on parameters in the clotting cascade: a multicenter, double-blind, randomized study

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Tibolone prevents atherosclerotic lesion formation in cholesterol-fed, ovariectomized rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

Tibolone inhibits leukocyte adhesion molecule expression in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-0760%2801%2900044-9

7 January 2021

10.1016/S0960-0760(01)00044-9

Identifiers

DOI

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1 August 2017

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PubMed ID

11384882