Programmed Application of Transforming Growth Factor β3 and Rac1 Inhibitor NSC23766 Committed Hyaline Cartilage Differentiation of Adipose-Derived Stem Cells for Osteochondral Defect Repair. (Q34273099)

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English	Programmed Application of Transforming Growth Factor β3 and Rac1 Inhibitor NSC23766 Committed Hyaline Cartilage Differentiation of Adipose-Derived Stem Cells for Osteochondral Defect Repair.	scientific article

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13 March 2020

Programmed Application of Transforming Growth Factor β3 and Rac1 Inhibitor NSC23766 Committed Hyaline Cartilage Differentiation of Adipose-Derived Stem Cells for Osteochondral Defect Repair (English)

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13 March 2020

N6-[2-[5-(diethylamino)pentan-2-ylamino]-6-methyl-4-pyrimidinyl]-2-methylquinoline-4,6-diamine

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ChEBI release 2020-05-28

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5

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13 March 2020

author name string

Shouan Zhu

1

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13 March 2020

Pengfei Chen

2

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13 March 2020

Yan Wu

3

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13 March 2020

Si Xiong

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13 March 2020

Qingqing Xia

6

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13 March 2020

Libing Shi

7

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13 March 2020

Huanhuan Liu

8

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13 March 2020

Hong Wei Ouyang

9

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13 March 2020

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25 August 2014

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13 March 2020

Stem Cells Translational Medicine

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13 March 2020

3

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13 March 2020

10

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13 March 2020

1242-1251

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13 March 2020

Current concepts of articular cartilage restoration techniques in the knee

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181399

6 July 2018

Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181399

6 July 2018

Adipose-derived mesenchymal stem cells for cartilage tissue engineering: state-of-the-art in in vivo studies

1 reference

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6 July 2018

Rac1 is required for matrix metalloproteinase 13 production by chondrocytes in response to fibronectin fragments

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6 July 2018

Regeneration of articular cartilage of the knee

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6 July 2018

Enhanced cartilage formation via three-dimensional cell engineering of human adipose-derived stem cells

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6 July 2018

Transient exposure to TGF-β3 improves the functional chondrogenesis of MSC-laden hyaluronic acid hydrogels

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6 July 2018

Hyaluronic acid (Supartz®): a review of its use in osteoarthritis of the knee

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6 July 2018

Strategies for articular cartilage lesion repair and functional restoration

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6 July 2018

Mechanics and mechanobiology of mesenchymal stem cell-based engineered cartilage

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6 July 2018

Stepwise differentiation of human embryonic stem cells promotes tendon regeneration by secreting fetal tendon matrix and differentiation factors.

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6 July 2018

Hyaluronan inhibits expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181399

6 July 2018

Rac1 signaling stimulates N-cadherin expression, mesenchymal condensation, and chondrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181399

6 July 2018

In vivo induction of mucosal immune responses by intranasal administration of chitosan microspheres containing Bordetella bronchiseptica DNT.

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6 July 2018

Review: mesenchymal stem cells: cell-based reconstructive therapy in orthopedics

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6 July 2018

Rac1/Cdc42 and RhoA GTPases antagonistically regulate chondrocyte proliferation, hypertrophy, and apoptosis

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6 July 2018

The human adipose tissue is a source of multipotent stem cells.

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6 July 2018

Biodegradable mucoadhesive particulates for nasal and pulmonary antigen and DNA delivery

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6 July 2018

Developmental regulation of the growth plate

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6 July 2018

Human adipose tissue is a source of multipotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181399

6 July 2018

Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects

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6 July 2018

Intranasal delivery of morphine

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6 July 2018

Multilineage cells from human adipose tissue: implications for cell-based therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4181399

6 July 2018

Tissue engineering of articular cartilage with autologous cultured adipose tissue-derived stromal cells using atelocollagen honeycomb-shaped scaffold with a membrane sealing in rabbits.

1 reference

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21 January 2018

Healing full-thickness cartilage defects using adipose-derived stem cells.

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21 January 2018

Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source.

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21 January 2018

Do adipose tissue-derived mesenchymal stem cells have the same osteogenic and chondrogenic potential as bone marrow-derived cells?

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21 January 2018

A comparison between the chondrogenic potential of human bone marrow stem cells (BMSCs) and adipose-derived stem cells (ADSCs) taken from the same donors.

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21 January 2018

Chondrogenic differentiation of adipose tissue-derived mesenchymal stem cells: greater doses of growth factor are necessary

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21 January 2018

Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification.

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21 January 2018

Genetic ablation of Rac1 in cartilage results in chondrodysplasia.

1 reference

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21 January 2018

Development and characterization of mucoadhesive microspheres bearing salbutamol for nasal delivery

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21 January 2018

International Cartilage Repair Society (ICRS) and Oswestry macroscopic cartilage evaluation scores validated for use in Autologous Chondrocyte Implantation (ACI) and microfracture.

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21 January 2018

Adipose tissue-derived stem cells show both immunogenic and immunosuppressive properties after chondrogenic differentiation

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21 January 2018

Chondrogenic potential of bone marrow- and adipose tissue-derived adult human mesenchymal stem cells

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28 October 2018

Histological assessment of cartilage repair: a report by the Histology Endpoint Committee of the International Cartilage Repair Society (ICRS)

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28 October 2018

Effectiveness of intra-articular hyaluronan (Synvisc, hylan G-F 20) for the treatment of first metatarsophalangeal joint osteoarthritis: a randomised placebo-controlled trial

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21 January 2018

Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice

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12 December 2020

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Magnetic resonance imaging appearance of cartilage repair in the knee

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12 December 2020

based on heuristic

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Results after microfracture of full-thickness chondral defects in different compartments in the knee

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12 December 2020

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Repair of osteochondral defects with adipose stem cells and a dual growth factor-releasing scaffold in rabbits

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12 December 2020

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The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study

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12 December 2020

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SOX trio-co-transduced adipose stem cells in fibrin gel to enhance cartilage repair and delay the progression of osteoarthritis in the rat

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12 December 2020

based on heuristic

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Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age

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12 December 2020

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Chondrogenic Differentiation of Mesenchymal Stem Cells from Bone Marrow: Differentiation-Dependent Gene Expression of Matrix Components

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12 December 2020

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Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo

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12 December 2020

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Identifiers

10.5966/SCTM.2014-0042

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13 March 2020

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13 March 2020

PubMed publication ID

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13 March 2020

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