Apoptotic death sensor: an organelle's alter ego? (Q34275400)

1 August 2017

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title

Apoptotic death sensor: an organelle's alter ego? (English)

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1 August 2017

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Bratton SB

1

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1 August 2017

Cohen GM

series ordinal

2

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1 August 2017

publication date

1 June 2001

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Trends in Pharmacological Sciences

1 August 2017

published in

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1 August 2017

volume

22

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1 August 2017

issue

6

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1 August 2017

page(s)

306-315

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Apoptosis in human disease: a new skin for the old ceremony?

1 August 2017

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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Structural basis of IAP recognition by Smac/DIABLO

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Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

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The IAP proteins: caspase inhibitors and beyond

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Molecular mechanisms of apoptosis induced by cytotoxic chemicals

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome complex

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Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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BH3-Only proteins-essential initiators of apoptotic cell death

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7 January 2021

Surfing the p53 network

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis

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7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

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Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

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7 January 2021

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7 January 2021

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

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7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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7 January 2021

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

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7 January 2021

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

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7 January 2021

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

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7 January 2021

Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

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7 January 2021

ASK1 is essential for JNK/SAPK activation by TRAF2

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7 January 2021

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

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7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

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7 January 2021

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

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7 January 2021

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7 January 2021

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7 January 2021

Understanding IAP function and regulation: a view from Drosophila

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7 January 2021

An emerging blueprint for apoptosis in Drosophila

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7 January 2021

Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway

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7 January 2021

BCL-2 family members and the mitochondria in apoptosis

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7 January 2021

Debcl, a proapoptotic Bcl-2 homologue, is a component of the Drosophila melanogaster cell death machinery.

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7 January 2021

A novel activation mechanism of caspase-activated DNase from Drosophila melanogaster

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7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

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7 January 2021

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Identifiers

DOI

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1 August 2017

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