The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions (Q34278218)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22649411%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions (English)

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2 February 2020

1

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2 February 2020

author name string

Peter Meinardus T Deen

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22649411%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Joris Hubertus Robben

series ordinal

3

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2 February 2020

publication date

16 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22649411%20AND%20SRC:MED&resulttype=core&format=json

Frontiers in Endocrinology

2 February 2020

published in

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2 February 2020

volume

3

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2 February 2020

page(s)

22

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Discovery of a potent and selective small molecule hGPR91 antagonist.

2 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Metabolic signatures of exercise in human plasma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Succinate modulates Ca(2+) transient and cardiomyocyte viability through PKA-dependent pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

The evolving story of the RAAS in hypertension, diabetes and CV disease: moving from macrovascular to microvascular targets

6 July 2018

1 reference

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Review article: Kidney dendritic cells: their role in homeostasis, inflammation and transplantation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Activation of the succinate receptor GPR91 in macula densa cells causes renin release.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

The role of the GPR91 ligand succinate in hematopoiesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Anatomical profiling of G protein-coupled receptor expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Triggering the succinate receptor GPR91 on dendritic cells enhances immunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Mitochondria and cellular oxygen sensing in the HIF pathway.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Transporter-mediated uptake into cellular compartments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Circulating succinate is elevated in rodent models of hypertension and metabolic disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

6 July 2018

1 reference

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Gene expression profiles during hepatic stellate cell activation in culture and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Succinate is a paracrine signal for liver damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

The pathobiology of diabetic complications: a unifying mechanism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

The role of mitochondria in ischemia/reperfusion injury in organ transplantation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

The SLC13 gene family of sodium sulphate/carboxylate cotransporters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Elements of a paracrine tubular renin-angiotensin system along the entire nephron

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Rate control of the tricarboxylic acid cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Effects of ischaemia on content of metabolites in rat liver and kidney in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Succinate accumulation in man during exercise

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Intratubular Renin-Angiotensin System in Hypertension.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Activation of the renal renin-angiotensin system in diabetes--new concepts.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Analysis of dicarboxylic acids by tandem mass spectrometry. High-throughput quantitative measurement of methylmalonic acid in serum, plasma, and urine.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Tricarboxylic acid cycle intermediate pool size and estimated cycle flux in human muscle during exercise.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355999

Involvement of extracellular signal-regulated kinase and p38 in human diabetic nephropathy

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22649411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nonezymatic formation of succinate in mitochondria under oxidative stress

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22649411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Succinate independently stimulates full platelet activation via cAMP and phosphoinositide 3-kinase-β signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22649411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FENDO.2012.00022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22649411%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22649411%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

22649411

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22649411%20AND%20SRC:MED&resulttype=core&format=json