Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate (Q34278840)

1 August 2017

title

Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate (English)

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1 August 2017

Srikanth C Nallani

1

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1 August 2017

Tracy A Glauser

2

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1 August 2017

Niresh Hariparsad

3

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1 August 2017

Kenneth Setchell

4

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1 August 2017

Donna J Buckley

5

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1 August 2017

Arthur R Buckley

6

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1 August 2017

Pankaj B Desai

7

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1 August 2017

language of work or name

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1 December 2003

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1 August 2017

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1 August 2017

volume

44

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1 August 2017

issue

12

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1 August 2017

page(s)

1521-1528

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Effect of topiramate or carbamazepine on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in healthy obese and nonobese female subjects

1 August 2017

cites work

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Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen

21 January 2018

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Induction of cytochrome P4503A by taxol in primary cultures of human hepatocytes

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Increased activity of CYP3A enzyme in primary cultures of rat hepatocytes treated with docetaxel: comparative evaluation with paclitaxel

21 January 2018

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Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans

21 January 2018

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

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Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction

21 January 2018

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The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

21 January 2018

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Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR

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Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

21 January 2018

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The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR

21 January 2018

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CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes

21 January 2018

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The importance of drug interactions in epilepsy therapy

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21 January 2018

Identifiers

DOI

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1 August 2017

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