AP-1 in mouse development and tumorigenesis (Q34279346)

1 August 2017

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title

AP-1 in mouse development and tumorigenesis (English)

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1 August 2017

Wagner EF

3

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author name string

Jochum W

series ordinal

1

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1 August 2017

Passegué E

series ordinal

2

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1 August 2017

language of work or name

English

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publication date

1 April 2001

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1 August 2017

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1 August 2017

20

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1 August 2017

2401-2412

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1 August 2017

19

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204389

1 August 2017

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cites work

The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Role of DNA 5-methylcytosine transferase in cell transformation by fos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Increase in AP-1 activity is a general event in thyroid cell transformation in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Transcriptional activation of the fra-1 gene by AP-1 is mediated by regulatory sequences in the first intron

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Induction of apoptosis by the transcription factor c-Jun

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Fos family members induce cell cycle entry by activating cyclin D1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

A defect in nurturing in mice lacking the immediate early gene fosB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Cascade induction of c-fos, c-myc, and heat shock 70K transcripts during regression of the rat ventral prostate gland

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Overexpression of the FosB2 gene in thymocytes causes aberrant development of T cells and thymic epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Overexpression of c-jun, junB, or junD affects cell growth differently

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The repertoire of fos and jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Structure of the FBJ Murine Osteosarcoma Virus Genome: Molecular Cloning of Its Associated Helper Virus and the Cellular Homolog of the v-fos Gene from Mouse and Human Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Functions of c-Jun in liver and heart development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Apoptosis during castration-induced regression of the prostate is Fos dependent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Growth and differentiation of embryonic stem cells that lack an intact c-fos gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Fra-1 replaces c-Fos-dependent functions in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

A novel, transformation-relevant activation domain in Fos proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

C-Fos is not essential for apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Osteoblasts are target cells for transformation in c-fos transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

c-Jun is essential for normal mouse development and hepatogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Normal peripheral T-cell function in c-Fos-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Structure-function analysis of fos protein: A single amino acid change activates the immortalizing potential of v-fos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Cellular transformation and malignancy induced by ras require c-jun

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Pleiotropic effects of a null mutation in the c-fos proto-oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Regulation of a multigenic invasion programme by the transcription factor, AP-1: re-expression of a down-regulated gene, TSC-36, inhibits invasion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

JunD mutants with spontaneously acquired transforming potential have enhanced transactivating activity in combination with Fra-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The genetic transformation of bone biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Expression of different Jun and Fos proteins during the G0-to-G1 transition in mouse fibroblasts: in vitro and in vivo associations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Fra-1 induces morphological transformation and increases in vitro invasiveness and motility of epithelioid adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Transformation suppressor activity of a Jun transcription factor lacking its activation domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Avian sarcoma virus 17 carries the jun oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

c-fos-induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Overexpression of fra-2 in transgenic mice perturbs normal eye development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Transformation by ras modifies AP1 composition and activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

c-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Alternative splicing of fosB transcripts results in differentially expressed mRNAs encoding functionally antagonistic proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Isolation and characterization of fra-2, an additional member of the fos gene family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Fra-1 potentiates osteoclastic differentiation in osteoclast-macrophage precursor cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Chronic Myeloid Leukemia with Increased Granulocyte Progenitors in Mice Lacking JunB Expression in the Myeloid Lineage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

AP-1 transcription factors: short- and long-term modulators of gene expression in the brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Induction of apoptosis by c-Fos protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Overexpression of DeltaFosB transcription factor(s) increases bone formation and inhibits adipogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

c-fos is required for malignant progression of skin tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

JunB is essential for mammalian placentation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Control of cell cycle progression by c-Jun is p53 dependent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Obligatory wounding requirement for tumorigenesis in v-jun transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Transcriptional activation and transformation by FosB protein require phosphorylation of the carboxyl-terminal activation domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Temporal and spatial expression of a fos-lacZ transgene in the developing nervous system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

fos-lacZ transgenic mice: mapping sites of gene induction in the central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Continuous c-fos expression precedes programmed cell death in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Bone and haematopoietic defects in mice lacking c-fos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

JunD protects cells from p53-dependent senescence and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

ECM and cell surface proteolysis: regulating cellular ecology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Transformation by Fos proteins requires a C-terminal transactivation domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Transformation by FosB requires a trans-activation domain missing in FosB2 that can be substituted by heterologous activation domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

An alternative spliced form of FosB is a negative regulator of transcriptional activation and transformation by Fos proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204389

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204389

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference