Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene libraries (Q34281020)

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20 October 2019

title

Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene libraries (English)

1 reference

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20 October 2019

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5

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20 October 2019

author name string

S J Deng

1

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20 October 2019

C R MacKenzie

2

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20 October 2019

T Hirama

3

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20 October 2019

R Brousseau

4

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20 October 2019

N M Young

6

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20 October 2019

D R Bundle

7

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20 October 2019

S A Narang

8

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20 October 2019

language of work or name

English

0 references

publication date

1 May 1995

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Proceedings of the National Academy of Sciences of the United States of America

20 October 2019

published in

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20 October 2019

volume

92

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20 October 2019

issue

11

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20 October 2019

page(s)

4992-4996

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Simultaneous randomization of antibody CDRs by a synthetic ligase chain reaction strategy

20 October 2019

cites work

1 reference

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Phage display and selection of a site-directed randomized single-chain antibody Fv fragment for its affinity improvement.

6 July 2018

1 reference

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"Diabodies": small bivalent and bispecific antibody fragments

6 July 2018

1 reference

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In vitro evolution of a neutralizing human antibody to human immunodeficiency virus type 1 to enhance affinity and broaden strain cross-reactivity

6 July 2018

1 reference

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Selection of antibody single-chain variable fragments with improved carbohydrate binding by phage display

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Anatomy of the antibody molecule

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Isolation of high affinity human antibodies directly from large synthetic repertoires.

6 July 2018

1 reference

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Human anti-self antibodies with high specificity from phage display libraries

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Structure of a single-chain antibody variable domain (Fv) fragment complexed with a carbohydrate antigen at 1.7-A resolution

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Molecular recognition of a Salmonella trisaccharide epitope by monoclonal antibody Se155-4.

6 July 2018

1 reference

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Domain association in immunoglobulin molecules. The packing of variable domains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Mutation drift and repertoire shift in the maturation of the immune response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

A complete library of point substitution mutations in the glucocorticoid response element of mouse mammary tumor virus

6 July 2018

1 reference

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Recognition of a Cell-Surface Oligosaccharide of Pathogenic Salmonella by an Antibody Fab Fragment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Sensitive titration microcalorimetric study of the binding of Salmonella O-antigenic oligosaccharides by a monoclonal antibody

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

In vitro selection and affinity maturation of antibodies from a naive combinatorial immunoglobulin library

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Selection of phage antibodies by binding affinity. Mimicking affinity maturation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Antibody engineering by codon-based mutagenesis in a filamentous phage vector system.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Thermodynamics of oligosaccharide binding to a monoclonal antibody specific for a Salmonella O-antigen point to hydrophobic interactions in the binding site

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Building Antibodies from their Genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Probing the combining site of an anti-carbohydrate antibody by saturation-mutagenesis: role of the heavy-chain CDR3 residues.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Effect of C lambda-C kappa domain switching on Fab activity and yield in Escherichia coli: synthesis and expression of genes encoding two anti-carbohydrate Fabs.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Variable domain-identical antibodies exhibit IgG subclass-related differences in affinity and kinetic constants as determined by surface plasmon resonance.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=41833

Multivalent Fvs: characterization of single-chain Fv oligomers and preparation of a bispecific Fv

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7539139

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multimerization behaviour of single chain Fv variants for the tumour-binding antibody B72.3.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7539139

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The influence of polyvalency on the binding properties of antibodies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7539139

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.92.11.4992

1 reference

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20 October 2019

0 references

1 reference

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20 October 2019

PubMed publication ID

7539139

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7539139%20AND%20SRC:MED&resulttype=core&format=json