Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia. (Q34282323)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20606166%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia (English)

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3

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Gail H Vance

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author name string

Anna C Pulliam-Leath

1

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Samantha L Ciccone

2

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Xiaxin Li

4

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Yue Si

5

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Leticia Miravalle

6

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Danielle Smith

7

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Jin Yuan

8

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Jingling Li

9

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Praveen Anur

10

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Attilio Orazi

11

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Feng-Chun Yang

13

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Helmut Hanenberg

14

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Grover C Bagby

15

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D Wade Clapp

16

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7 February 2020

language of work or name

English

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publication date

6 July 2010

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7 February 2020

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volume

116

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issue

16

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page(s)

2915-2920

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Mouse models of Fanconi anemia

7 February 2020

cites work

1 reference

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The genetic and molecular basis of Fanconi anemia

6 July 2018

1 reference

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FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

6 July 2018

1 reference

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Overnight transduction with foamyviral vectors restores the long-term repopulating activity of Fancc-/- stem cells

6 July 2018

1 reference

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FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

6 July 2018

1 reference

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FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

6 July 2018

1 reference

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Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

6 July 2018

1 reference

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Fanconi anemia is associated with a defect in the BRCA2 partner PALB2.

6 July 2018

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Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

6 July 2018

1 reference

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Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia

6 July 2018

1 reference

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6 July 2018

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Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options

6 July 2018

1 reference

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Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2.

6 July 2018

1 reference

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The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Molecular pathogenesis of Fanconi anemia: recent progress

6 July 2018

1 reference

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Fanconi anemia (cross)linked to DNA repair

6 July 2018

1 reference

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FANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

6 July 2018

1 reference

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X-linked inheritance of Fanconi anemia complementation group B

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin

6 July 2018

1 reference

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Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways

6 July 2018

1 reference

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A novel ubiquitin ligase is deficient in Fanconi anemia

6 July 2018

1 reference

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Genetic basis of Fanconi anemia

6 July 2018

1 reference

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The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Fanconi anemia group A and C double-mutant mice: functional evidence for a multi-protein Fanconi anemia complex.

6 July 2018

1 reference

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Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways

6 July 2018

1 reference

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Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9

6 July 2018

1 reference

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The Fanconi anemia complementation group C gene product: structural evidence of multifunctionality

6 July 2018

1 reference

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Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Hematologic abnormalities in Fanconi anemia: an International Fanconi Anemia Registry study.

6 July 2018

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Bone marrow transplantation for Fanconi anemia.

6 July 2018

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Cytogenetic methods for the mouse: preparation of chromosomes, karyotyping, and in situ hybridization

6 July 2018

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Leukemia and preleukemia in Fanconi anemia patients. A review of the literature and report of the International Fanconi Anemia Registry

6 July 2018

1 reference

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Clonal and systemic analysis of long-term hematopoiesis in the mouse.

6 July 2018

1 reference

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The identification in adult bone marrow of pluripotent and restricted stem cells of the myeloid and lymphoid systems

6 July 2018

1 reference

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Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M.

6 July 2018

1 reference

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Identification of the Fanconi anemia complementation group I gene, FANCI.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis

28 October 2018

1 reference

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Cancer in Fanconi anemia.

28 October 2018

1 reference

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Clonal chromosomal aberrations in bone marrow cells of Fanconi anemia patients: gains of the chromosomal segment 3q26q29 as an adverse risk factor.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

A 20-year perspective on the International Fanconi Anemia Registry (IFAR).

28 October 2018

1 reference

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Loss of FancC function results in decreased hematopoietic stem cell repopulating ability.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974601

Competitive repopulation: a new assay for long-term stem cell functional capacity

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20606166

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heterozygosity for p53 (Trp53+/-) accelerates epithelial tumor formation in fanconi anemia complementation group D2 (Fancd2) knockout mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20606166

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A major switch for the Fanconi anemia DNA damage-response pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20606166

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2009-08-240747

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20606166%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20606166%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

20606166

1 reference