Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression (Q34282466)

1 August 2017

Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression (English)

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1 August 2017

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Mark S Kramer

1

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1 August 2017

Andrew Winokur

2

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1 August 2017

Jeffrey Kelsey

3

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1 August 2017

Sheldon H Preskorn

4

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1 August 2017

Anthony J Rothschild

5

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1 August 2017

Duane Snavely

6

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1 August 2017

Kalyan Ghosh

7

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1 August 2017

William A Ball

8

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1 August 2017

Scott A Reines

9

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1 August 2017

Dennis Munjack

10

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1 August 2017

Jeffrey T Apter

11

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1 August 2017

Lynn Cunningham

12

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1 August 2017

Mitchel Kling

13

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1 August 2017

Mohammed Bari

14

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1 August 2017

Albert Getson

15

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1 August 2017

Yih Lee

16

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1 August 2017

language of work or name

English

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publication date

1 February 2004

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1 August 2017

Neuropsychopharmacology

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1 August 2017

29

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2

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1 August 2017

385-392

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https://scigraph.springernature.com/pub.10.1038/sj.npp.1300260

1 August 2017

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cites work

Perturbation of Rat Brain Serotonergic Systems Results in an Inverse Relation Between Substance P and Serotonin Concentrations Measured in Discrete Nuclei

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Intra-amygdala injection of the substance P [NK(1) receptor] antagonist L-760735 inhibits neonatal vocalisations in guinea-pigs.

21 January 2018

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Norepinephrine in depressive reactions. A review

21 January 2018

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Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils.

21 January 2018

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Central tachykinins: mediators of defence reaction and stress reactions

21 January 2018

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Alcohol consumption and lifestyle in medical students.

21 January 2018

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Neuroendocrine and behavioral effects of dietary tryptophan restriction in healthy subjects.

21 January 2018

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Phylogeny of tachykinin receptor localization in the vertebrate central nervous system: apparent absence of neurokinin-2 and neurokinin-3 binding sites in the human brain

21 January 2018

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A molecular and cellular theory of depression

21 January 2018

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Evidence for a tonic facilitatory influence of substance P on dopamine release in the nucleus accumbens

21 January 2018

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Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones

21 January 2018

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Response patterns of depressed outpatients with and without melancholia: a double-blind, placebo-controlled trial of fluoxetine versus placebo.

21 January 2018

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Molecular characterization of a functional cDNA encoding the rat substance P receptor

21 January 2018

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Neuropeptides in perspective: the last ten years

21 January 2018

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Isolation and characterisation of the human lung NK-1 receptor cDNA

21 January 2018

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Distinct mechanism for antidepressant activity by blockade of central substance P receptors

21 January 2018

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Compared Efficacy of Prazepam and Clomipramine in Major Depression with Anxiety: a Multicenter Controlled Study

21 January 2018

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Suppressant effects of dexamethasone on the availability of plasma L-tryptophan and tyrosine in healthy controls and in depressed patients.

21 January 2018

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The mammalian tachykinin receptors

21 January 2018

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cDNA cloning of bovine substance-K receptor through oocyte expression system.

21 January 2018

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Chronic substance P (NK1) receptor antagonist and conventional antidepressant treatment increases burst firing of monoamine neurones in the locus coeruleus

21 January 2018

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SSRI-induced sexual dysfunction: fluoxetine, paroxetine, sertraline, and fluvoxamine in a prospective, multicenter, and descriptive clinical study of 344 patients.

21 January 2018

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Molecular and cellular mechanisms of antidepressant drugs

21 January 2018

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Melancholic/endogenous depression and response to somatic treatment and placebo

21 January 2018

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Neurokinin receptor subtypes characterized by biological assays

21 January 2018

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Characterization of the binding of [125I-iodo-histidyl, methyl-Phe7] neurokinin B to the neurokinin-3 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

The catecholamine hypothesis of affective disorders: a review of supporting evidence

21 January 2018

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Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat.

21 January 2018

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Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat.

21 January 2018

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Substance P induces a cardiovascular defense reaction in the rat: pharmacological characterization

21 January 2018

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Dopamine and depression: A review of recent evidence. I. Empirical studies

21 January 2018

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Tryptophan depletion causes a rapid lowering of mood in normal males

21 January 2018

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Increased serotonin2 (5-HT2) receptor binding as measured by 3H-lysergic acid diethylamide (3H-LSD) in the blood platelets of depressed patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Effects of subchronic treatment with imipramine, zimelidine and alaproclate on regional tissue levels of substance P-and neurokinin a/neurokinin B-like immunoreactivity in the brain and spinal cord of the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

A neuroendocrine study of 5HT function in depression: evidence for biological mechanisms of endogenous and psychosocial causation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Stress-induced C-fos expression in the rat locus coeruleus is dependent on neurokinin 1 receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Plasma ratio tryptophan/neutral amino acids in relation to clinical response to paroxetine and clomipramine in patients with major depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Neurotransmitter functions of mammalian tachykinins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Decreased plasma serotonin in melancholic patients: A study with clomipramine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

The substance P antagonist L-760,735 inhibits stress-induced NK(1) receptor internalisation in the basolateral amygdala

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Pharmacological and molecular biological studies on the diversity of rat tachykinin NK-2 receptor subtypes in rat CNS, duodenum, vas deferens, and urinary bladder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

The tachykinin NK1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Enantioselective inhibition of apomorphine-induced emesis in the ferret by the neurokinin1 receptor antagonist CP-99,994

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Blunted growth hormone and prolactin responses to L-tryptophan in depression; a state-dependent abnormality

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1300260

7 January 2021

Identifiers

DOI

10.1038/SJ.NPP.1300260

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Dimensions Publication ID

1 August 2017

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