Ocular immune privilege: therapeutic opportunities from an experiment of nature (Q34282825)

1 August 2017

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title

Ocular immune privilege: therapeutic opportunities from an experiment of nature (English)

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1 August 2017

J Wayne Streilein

1

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1 August 2017

1 November 2003

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Nature Reviews Immunology

1 August 2017

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1 August 2017

3

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1 August 2017

11

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1 August 2017

879-889

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Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments

1 August 2017

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Unraveling immune privilege

31 March 2020

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Does innate immune privilege exist?

31 March 2020

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Allogeneic neonatal neuronal retina grafts display partial immune privilege in the subcapsular space of the kidney.

31 March 2020

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Lengthy regrowth of cut axons from ganglion cells after peripheral nerve transplantation into the retina of adult rats.

31 March 2020

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Immunology and immunomodulation of corneal transplantation

31 March 2020

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HLA antigens in ocular tissues. I. In vivo expression in human eyes

31 March 2020

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Orthotopic corneal transplantation in mice--evidence that the immunogenetic rules of rejection do not apply

31 March 2020

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Prolongation of rat corneal graft survival by treatment with anti-CD4 monoclonal antibody

31 March 2020

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Corneal allografts fail to express Ia antigens

31 March 2020

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The corneal stroma is endowed with a significant number of resident dendritic cells

31 March 2020

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Indirect presentation of MHC antigens in transplantation

31 March 2020

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Indirect recognition by helper cells can induce donor-specific cytotoxic T lymphocytes in vivo

31 March 2020

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Immunobiology of tissue transplantation: a return to the passenger leukocyte concept

31 March 2020

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Corneal lymphangiogenesis: evidence, mechanisms, and implications for corneal transplant immunology

31 March 2020

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CD4+ T cells are critical for corneal, but not skin, allograft rejection

31 March 2020

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An improved method for examining the corneal endothelium during graft rejection in the rat

31 March 2020

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Detection of minor alloantigen-specific cytotoxic T cells after rejection of murine orthotopic corneal allografts: evidence that graft antigens are recognized exclusively via the "indirect pathway"

31 March 2020

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Draining lymph nodes of corneal transplant hosts exhibit evidence for donor major histocompatibility complex (MHC) class II-positive dendritic cells derived from MHC class II-negative grafts

31 March 2020

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Systemic immune unresponsiveness induced in adult mice by anterior chamber presentation of minor histocompatibility antigens

31 March 2020

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CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site.

31 March 2020

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MIP-2 recruits NKT cells to the spleen during tolerance induction

31 March 2020

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NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance

31 March 2020

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NKT cell-derived RANTES recruits APCs and CD8+ T cells to the spleen during the generation of regulatory T cells in tolerance

31 March 2020

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Splenic B cells are required for tolerogenic antigen presentation in the induction of anterior chamber-associated immune deviation (ACAID)

31 March 2020

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CD1d on antigen-transporting APC and splenic marginal zone B cells promotes NKT cell-dependent tolerance

31 March 2020

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Gamma delta T cells are needed for ocular immune privilege and corneal graft survival

31 March 2020

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Ocular immune privilege promoted by the presentation of peptide on tolerogenic B cells in the spleen. II. Evidence for presentation by Qa-1

31 March 2020

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Anterior chamber associated immune deviation (ACAID): regulation, biological relevance, and implications for therapy

31 March 2020

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The eye's view of antigen presentation

31 March 2020

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Studies on the induction of anterior chamber-associated immune deviation (ACAID). III. Induction of ACAID depends upon intraocular transforming growth factor-beta

31 March 2020

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Expression of thrombospondin in TGFbeta-treated APCs and its relevance to their immune deviation-promoting properties

31 March 2020

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Induction of donor-specific ACAID can prolong orthotopic corneal allograft survival in "high-risk" eyes

31 March 2020

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Using tolerance induced via the anterior chamber of the eye to inhibit Th2-dependent pulmonary pathology.

31 March 2020

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Somatostatin is an immunosuppressive factor in aqueous humor

31 March 2020

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Identification of alpha-melanocyte stimulating hormone as a potential immunosuppressive factor in aqueous humor

31 March 2020

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Membrane Fas ligand activates innate immunity and terminates ocular immune privilege

31 March 2020

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Ocular immune privilege and the impact of intraocular inflammation.

31 March 2020

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Analysis of immunomodulatory activities of aqueous humor from eyes of mice with experimental autoimmune uveitis

31 March 2020

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Immune privilege persists in eyes with extreme inflammation induced by intravitreal LPS

31 March 2020

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Cell death and immune privilege

31 March 2020

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Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

31 March 2020

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CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival

31 March 2020

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Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants.

31 March 2020

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Iris pigment epithelium expressing CD86 (B7-2) directly suppresses T cell activation in vitro via binding to cytotoxic T lymphocyte-associated antigen 4.

31 March 2020

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Survival in high-risk eyes of epithelium-deprived orthotopic corneal allografts reconstituted in vitro with syngeneic epithelium

31 March 2020

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Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

31 March 2020

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Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing

31 March 2020

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Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival

31 March 2020

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Expression of a nonclassical MHC class Ib molecule in the eye

31 March 2020

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Immunity causing blindness: five different paths to herpes stromal keratitis

31 March 2020

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Interleukin 4 and T helper type 2 cells are required for development of experimental onchocercal keratitis (river blindness).

31 March 2020

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Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells

31 March 2020

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Thrombospondin-1, a natural inhibitor of angiogenesis, is present in vitreous and aqueous humor and is modulated by hyperglycemia

31 March 2020

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Novel production of interleukin-1 receptor antagonist peptides in normal human cornea

31 March 2020

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Soluble Fas ligand and soluble Fas in ocular fluid of patients with uveitis

31 March 2020

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Studies on the problem of corneal homografts

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Regional immunity and ocular immune privilege

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1224

1 reference

1 August 2017

1 reference

PubMed ID

14668804