The same self-peptide selects conventional and regulatory CD4⁺ T cells with identical antigen receptors. (Q34284280)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270305%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

The same self-peptide selects conventional and regulatory CD4⁺ T cells with identical antigen receptors (English)

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6

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7

Pawel Kisielow

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20 February 2020

author name string

Lukasz Wojciech

1

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20 February 2020

Alicja Ignatowicz

2

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20 February 2020

Michal Seweryn

3

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20 February 2020

Grzegorz Rempala

4

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20 February 2020

Simarjot Singh Pabla

5

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20 February 2020

Leszek Ignatowicz

8

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20 February 2020

language of work or name

English

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publication date

1 October 2014

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20 February 2020

published in

Nature Communications

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20 February 2020

volume

5

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page(s)

5061

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https://scigraph.springernature.com/pub.10.1038/ncomms6061

20 February 2020

exact match

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cites work

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A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self.

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Quantitative impact of thymic selection on Foxp3+ and Foxp3- subsets of self-peptide/MHC class II-specific CD4+ T cells

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TCR-dependent differentiation of thymic Foxp3+ cells is limited to small clonal sizes

6 July 2018

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Foxp3-deficient regulatory T cells do not revert into conventional effector CD4+ T cells but constitute a unique cell subset

6 July 2018

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Intraclonal competition limits the fate determination of regulatory T cells in the thymus

6 July 2018

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Differentiation of regulatory Foxp3+ T cells in the thymic cortex

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Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells

6 July 2018

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Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells

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In the normal repertoire of CD4+ T cells, a single class II MHC/peptide complex positively selects TCRs with various antigen specificities

21 January 2018

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12 December 2020

An incremental increase in the complexity of peptides bound to class II MHC changes the diversity of positively selected alpha beta TCRs

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12 December 2020

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Identifiers

DOI

10.1038/NCOMMS6061

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270305%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 February 2020

ADS bibcode

2014NatCo...5.5061W

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0 references

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20 February 2020

1 reference

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