Quantifying selection in high-throughput Immunoglobulin sequencing data sets (Q34284964)

1 August 2017

Quantifying selection in high-throughput Immunoglobulin sequencing data sets (English)

1 reference

1 August 2017

Gur Yaari

1

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author name string

Mohamed Uduman

series ordinal

2

1 reference

PubMed ID

22641856

1 August 2017

Steven H Kleinstein

series ordinal

3

1 reference

PubMed ID

22641856

1 August 2017

language of work or name

English

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publication date

27 May 2012

1 reference

1 August 2017

Nucleic Acids Research

1 reference

1 August 2017

40

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1 August 2017

17

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1 August 2017

e134

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Creative Commons Attribution-NonCommercial 3.0 Unported

1 August 2017

start time

8 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Detecting selection in immunoglobulin sequences

1 reference

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Determinism and stochasticity during maturation of the zebrafish antibody repertoire

6 July 2018

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High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

6 July 2018

1 reference

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Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing

6 July 2018

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Taking advantage: high-affinity B cells in the germinal center have lower death rates, but similar rates of division, compared to low-affinity cells

6 July 2018

1 reference

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SHMTool: a webserver for comparative analysis of somatic hypermutation datasets

6 July 2018

1 reference

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IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

6 July 2018

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iHMMune-align: hidden Markov model-based alignment and identification of germline genes in rearranged immunoglobulin gene sequences

6 July 2018

1 reference

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Differences in potential for amino acid change after mutation reveals distinct strategies for kappa and lambda light-chain variation

6 July 2018

1 reference

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The application of statistical physics to evolutionary biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

The inference of antigen selection on Ig genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

Both DNA strands of antibody genes are hypermutation targets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

6 July 2018

1 reference

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Erroneous analyses of interactions in neuroscience: a problem of significance.

6 July 2018

1 reference

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Why do B cells mutate their immunoglobulin receptors?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection.

28 October 2018

1 reference

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Frequentist performance of Bayesian confidence intervals for comparing proportions in 2 x 2 contingency tables.

28 October 2018

1 reference

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Sequence-specific targeting of two bases on both DNA strands by the somatic hypermutation mechanism.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

Molecular analysis of immunoglobulin genes in diffuse large B-cell lymphomas.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

The nucleotide-replacement spectrum under somatic hypermutation exhibits microsequence dependence that is strand-symmetric and distinct from that under germline mutation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

Strong intrinsic biases towards mutation and conservation of bases in human IgVH genes during somatic hypermutation prevent statistical analysis of antigen selection.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

Improved methods for detecting selection by mutation analysis of Ig V region sequences

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

Determination of IGHV gene mutational status in chronic lymphocytic leukemia: bioinformatics advances meet clinical needs

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458526

The role of clonal selection and somatic mutation in autoimmunity

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22641856

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKS457

1 reference

1 August 2017

1 reference

1 August 2017

1 reference

PubMed ID

22641856