Mechanisms of interleukin-10-mediated immune suppression (Q34285968)

1 August 2017

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title

Mechanisms of interleukin-10-mediated immune suppression (English)

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1 August 2017

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C A Akdis

1

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PubMed ID

11412299

1 August 2017

K Blaser

series ordinal

2

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1 August 2017

1 June 2001

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1 August 2017

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1 August 2017

103

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1 August 2017

2

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1 August 2017

131-136

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Immunoregulatory T-cell pathways.

1 August 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Role of interleukin 10 in specific immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Induction of hapten-specific tolerance by interleukin 10 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Nasal challenge with ragweed pollen in hay fever patients. Effect of immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

The effect of immunotherapy on bronchial hyperresponsiveness and eosinophil cationic protein in pollen-allergic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Successful immunotherapy with T-cell epitope peptides of bee venom phospholipase A2 induces specific T-cell anergy in patients allergic to bee venom.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Insect venom immunotherapy induces interleukin-10 production and a Th2-to-Th1 shift, and changes surface marker expression in venom-allergic subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Effects of peptide therapy on ex vivo T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Long-term clinical efficacy of grass-pollen immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Regulation of specific immune responses by chemical and structural modifications of allergens

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Mechanisms of allergen-specific immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Peripheral T-cell tolerance induced in naive and primed mice by subcutaneous injection of peptides from the major cat allergen Fel d I

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Immunoglobulin E-independent major histocompatibility complex-restricted T cell peptide epitope-induced late asthmatic reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

The expanding universe of T-cell subsets: Th1, Th2 and more.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Interleukin (IL)-10 inhibits long-term IL-6 production but not preformed mediator release from rat peritoneal mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

IL-10: a potential therapy for allergic inflammation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Interleukin 10 inhibits lipopolysaccharide-induced survival and cytokine production by human peripheral blood eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

CD40 expression by human peripheral blood eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

PI 3-kinase: a pivotal pathway in T-cell activation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Functional regions of the mouse interleukin-10 receptor cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Identification and functional characterization of a second chain of the interleukin-10 receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

Molecular basis of T cell inactivation by CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2001.01235.X

A molecular basis for T cell suppression by IL-10: CD28-associated IL-10 receptor inhibits CD28 tyrosine phosphorylation and phosphatidylinositol 3-kinase binding

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

IL-10-induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

Differential regulation of human T cell cytokine patterns and IgE and IgG4 responses by conformational antigen variants.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

Defective TCR stimulation in anergized type 2 T helper cells correlates with abrogated p56(lck) and ZAP-70 tyrosine kinase activities.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

PI 3-kinase: structural and functional analysis of intersubunit interactions

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

Isotypic and idiotypic characterization of anti-bee venom phospholipase A2 antibodies.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

The genomic organization of the CD28 gene. Implications for the regulation of CD28 mRNA expression and heterogeneity

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

IL-10 inhibits cytokine production by activated macrophages

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783236

Maintenance of clonal anergy by endogenously produced IL-10

28 October 2018

1 reference

12 December 2020

Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures

1 reference

12 December 2020

Influence of bee venom immunotherapy on degranulation and leukotriene generation in human blood basophils

1 reference

12 December 2020

Treatment of cat allergy with T-cell reactive peptides

1 reference

12 December 2020

Induction and differential regulation of bee venom phospholipase A2-specific human IgE and IgG4 antibodies in vitro requires allergen-specific and nonspecific activation of T and B cells

1 reference

12 December 2020

Effect of preseasonal enzyme potentiated desensitisation (EPD) on plasma-IL-6 and IL-10 of grass pollen-sensitive asthmatic children

1 reference

12 December 2020

Nasal immunotherapy in weed-induced allergic rhinitis

1 reference

12 December 2020

Glucocorticoids inhibit human antigen-specific and enhance total IgE and IgG4 production due to differential effects on T and B cells in vitro

1 reference

12 December 2020

Interleukin-2 can prevent and reverse antigen-induced unresponsiveness in cloned human T lymphocytes

1 reference

12 December 2020

Regulation of human basophil mediator release by cytokines. I. Interaction with antiinflammatory steroids

1 reference

12 December 2020

Determinants and mechanisms of human immune responses to bee venom phospholipase A2

1 reference

12 December 2020

An altered peptide ligand specifically inhibits Th2 cytokine synthesis by abrogating TCR signaling

1 reference

12 December 2020

Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1

1 reference

12 December 2020

T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma

1 reference

12 December 2020

Control of allergic reactivity in human filariasis. Predominant localization of blocking antibody to the IgG4 subclass

1 reference

12 December 2020

Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production

1 reference

12 December 2020

T cell epitope specificity in human allergic and nonallergic subjects to bee venom phospholipase A2

1 reference

12 December 2020

10.1046/J.1365-2567.2001.01235.X

Identifiers

DOI

1 reference

1 August 2017

0 references

1 reference

PubMed ID

11412299