Laquinimod reduces neuroaxonal injury through inhibiting microglial activation. (Q34286754)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Laquinimod reduces neuroaxonal injury through inhibiting microglial activation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

V. Wee Yong

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Janet Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Michael B Keough

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Yan Fan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Claudia Silva

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Scott Sloka

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Liat Hayardeny

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Wolfgang Brück

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

publication date

26 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

Annals of clinical and translational neurology

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

409-422

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis

22 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Placebo-controlled trial of oral laquinimod in multiple sclerosis: MRI evidence of an effect on brain tissue damage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Reduction of microglial activity in a model of multiple sclerosis by dipyridamole.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Progressive multiple sclerosis: pathology and pathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Laquinimod, a once-daily oral drug in development for the treatment of relapsing-remitting multiple sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Placebo-controlled trial of oral laquinimod for multiple sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α-PU.1 pathway.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

The myeloid cells of the central nervous system parenchyma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Mechanisms underlying inflammation in neurodegeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

PKCdelta mediates Nrf2-dependent protection of neuronal cells from NO-induced apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Matrix metalloproteinase-12 deficiency worsens relapsing-remitting experimental autoimmune encephalomyelitis in association with cytokine and chemokine dysregulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4184669

Immunopathology of secondary-progressive multiple sclerosis.

6 July 2018

1 reference

Heterogeneity of cortical lesions in multiple sclerosis: clinical and pathologic implications.

21 January 2018

1 reference

Laquinimod (ABR-215062) suppresses the development of experimental autoimmune encephalomyelitis, modulates the Th1/Th2 balance and induces the Th3 cytokine TGF-beta in Lewis rats

21 January 2018

1 reference

Kinetics of proinflammatory monocytes in a model of multiple sclerosis and its perturbation by laquinimod.

21 January 2018

1 reference

Multiple sclerosis: Oral laquinimod for MS--bringing the brain into focus.

21 January 2018

1 reference

Laquinimod prevents inflammation-induced synaptic alterations occurring in experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis

21 January 2018

1 reference

Overcoming neurite-inhibitory chondroitin sulfate proteoglycans in the astrocyte matrix.

21 January 2018

1 reference

Additive effect of the combination of glatiramer acetate and minocycline in a model of MS.

21 January 2018

1 reference

The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation.

21 January 2018

1 reference

Poly(ADP-ribose) polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death

21 January 2018

1 reference

Cortical demyelination and diffuse white matter injury in multiple sclerosis.

21 January 2018

1 reference

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis

21 January 2018

1 reference

12 December 2020

Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo

1 reference

12 December 2020

Laquinimod modulates B cells and their regulatory effects on T cells in multiple sclerosis

1 reference

12 December 2020

Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Identifiers

DOI

10.1002/ACN3.67

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25356411%20AND%20SRC:MED&resulttype=core&format=json