Transient B cell depletion or improved transgene expression by codon optimization promote tolerance to factor VIII in gene therapy (Q34289040)

1 August 2017

title

Transient B cell depletion or improved transgene expression by codon optimization promote tolerance to factor VIII in gene therapy (English)

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1 August 2017

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5

Andrew M Davidoff

1 reference

1 August 2017

Brandon K Sack

1

1 reference

1 August 2017

Sherin Merchant

2

1 reference

1 August 2017

David M Markusic

3

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1 August 2017

Amit C Nathwani

4

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1 August 2017

Barry J Byrne

6

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1 August 2017

Roland W Herzog

7

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1 August 2017

language of work or name

English

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publication date

24 May 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

5

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1 August 2017

page(s)

e37671

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

24 May 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

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21 January 2018

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A single adeno-associated virus (AAV)-murine factor VIII vector partially corrects the hemophilia A phenotype

21 January 2018

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Immunoglobulin isotypes and functional anti-FVIII antibodies in response to FVIII treatment in Balb/c and C57BL/6 haemophilia A mice

21 January 2018

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High-level expression of porcine factor VIII from genetically modified bone marrow-derived stem cells

21 January 2018

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Codon optimization of human factor VIII cDNAs leads to high-level expression

21 January 2018

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21 January 2018

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Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

28 October 2018

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Codon and mRNA Sequence Optimization of Microdystrophin Transgenes Improves Expression and Physiological Outcome in Dystrophic mdx Mice Following AAV2/8 Gene Transfer

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22655063

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Optimising immune tolerance induction strategies in the management of haemophilia patients with inhibitors: a cost-minimisation analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22655063

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Durable responses to rituximab in acquired factor VIII deficiency

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22655063

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0037671

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference