Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds (Q34290022)

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English	Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds	scientific article

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10 February 2020

Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds (English)

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10 February 2020

Toxoplasma gondii

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Alexandre Bougdour

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10 February 2020

Mohamed-Ali Hakimi

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10 February 2020

Marie-Pierre Brenier-Pinchart

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Marie-Pierre Brenier-Pinchart

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10 February 2020

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Hervé Pelloux

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10 February 2020

Danièle Maubon

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Danièle Maubon

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10 February 2020

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Yung-Sing Wong

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10 February 2020

Aurélie Curt

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10 February 2020

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16 August 2010

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10 February 2020

Antimicrobial Agents and Chemotherapy

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10 February 2020

54

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10 February 2020

11

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10 February 2020

4843-4850

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10 February 2020

Toxoplasma gondii: 25 years and 25 major advances for the field

1 reference

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6 July 2018

Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

1 reference

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6 July 2018

Molecular approaches to diversity of populations of apicomplexan parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Toxoplasma gondii gene expression is under the control of regulatory pathways acting through chromatin structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Migration of Apicomplexa across biological barriers: the Toxoplasma and Plasmodium rides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Comparative genomics of transcription factors and chromatin proteins in parasitic protists and other eukaryotes

1 reference

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6 July 2018

Epigenetics in Apicomplexa: control of gene expression during cell cycle progression, differentiation and antigenic variation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Functions of site-specific histone acetylation and deacetylation

1 reference

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6 July 2018

Innovative lead discovery strategies for tropical diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Histone mediated gene activation in Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Biology and epidemiology of Toxoplasma gondii in man and animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Drug resistance hampers our capacity to roll back malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Toxoplasma gondii tachyzoite-bradyzoite interconversion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Treatment regimens for patients with toxoplasmic encephalitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Monoclonal rat antibodies directed against Toxoplasma gondii suitable for studying tachyzoite-bradyzoite interconversion in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Evaluation of the Effect of Drugs on the Cyst Form of Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

In vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against the cyst form of Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Specific Labeling of IntracellularToxoplasma gondiiwith Uracil*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

6 July 2018

Diagnosis of toxoplasmosis after allogeneic stem cell transplantation: results of DNA detection and serological techniques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

28 October 2018

The small ubiquitin-like modifier (SUMO)-conjugating system of Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

28 October 2018

In vitro susceptibility of various genotypic strains of Toxoplasma gondii to pyrimethamine, sulfadiazine, and atovaquone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

28 October 2018

Breakthrough cerebral toxoplasmosis in a patient receiving atovaquone prophylaxis after a hematopoietic stem cell transplantation

1 reference

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28 October 2018

Conformational flexibility, internal hydrogen bonding, and passive membrane permeability: successful in silico prediction of the relative permeabilities of cyclic peptides

1 reference

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28 October 2018

Stage-specific expression of surface antigens by Toxoplasma gondii as a mechanism to facilitate parasite persistence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

28 October 2018

FR235222, a fungal metabolite, is a novel immunosuppressant that inhibits mammalian histone deacetylase (HDAC). I. Taxonomy, fermentation, isolation and biological activities

1 reference

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28 October 2018

Randomized phase II trial of atovaquone with pyrimethamine or sulfadiazine for treatment of toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome: ACTG 237/ANRS 039 Study. AIDS Clinical Trials Group 237/Agence Nationale de Rec

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28 October 2018

Separation of Isospora (Toxoplasma) gondii cysts and cystozoites from mouse brain tissue by continuous density - gradient centrifugation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2976123

28 October 2018

Reactivation of toxoplasma retinochoroiditis under atovaquone therapy in an immunocompetent patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713670

12 December 2020

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The BSR4 protein is up-regulated in Toxoplasma gondii bradyzoites, however the dominant surface antigen recognised by the P36 monoclonal antibody is SRS9

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713670

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adapting a conventional PCR assay for Toxoplasma gondii detection to real-time quantitative PCR including a competitive internal control

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713670

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222

1 reference

https://pubmed.ncbi.nlm.nih.gov/20713670

12 December 2020

based on heuristic

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10.1128/AAC.00462-10

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10 February 2020

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10 February 2020

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10 February 2020

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