Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19. (Q34292701)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666415%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19 (English)

1 reference

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3 February 2020

0 references

1 reference

1

1 reference

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3 February 2020

Eline Slagboom

2

1 reference

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3 February 2020

Jenny van Dongen

3

1 reference

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3 February 2020

Aryeh D. Stein

5

1 reference

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3 February 2020

7

Bastiaan T Heijmans

1 reference

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3 February 2020

6

Hein Putter

1 reference

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3 February 2020

4

Dennis Kremer

1 reference

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3 February 2020

author name string

L H Lumey

8

1 reference

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3 February 2020

language of work or name

English

0 references

publication date

30 May 2012

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3 February 2020

1 reference

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3 February 2020

volume

7

1 reference

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3 February 2020

page(s)

e37933

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3 February 2020

issue

5

1 reference

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Creative Commons Attribution 4.0 International

3 February 2020

copyright license

start time

30 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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6 July 2018

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Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets

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Integrating common and rare genetic variation in diverse human populations

6 July 2018

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Leptin gene epigenetic adaptation to impaired glucose metabolism during pregnancy.

6 July 2018

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Association of birth weight with polymorphisms in the IGF2, H19, and IGF2R genes

6 July 2018

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Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain

6 July 2018

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6 July 2018

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Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects

6 July 2018

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Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus

6 July 2018

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Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child

6 July 2018

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6 July 2018

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An engineered zinc finger protein reveals a role for the insulin VNTR in the regulation of the insulin and adjacent IGF2 genes

6 July 2018

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DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

6 July 2018

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Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men

6 July 2018

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6 July 2018

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6 July 2018

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Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development

6 July 2018

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6 July 2018

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6 July 2018

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Persistent epigenetic differences associated with prenatal exposure to famine in humans

6 July 2018

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6 July 2018

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The thrifty epigenotype: an acquired and heritable predisposition for obesity and diabetes?

6 July 2018

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Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements

6 July 2018

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Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women

6 July 2018

1 reference

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6 July 2018

1 reference

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6 July 2018

1 reference

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Epigenetic modification of the renin-angiotensin system in the fetal programming of hypertension

6 July 2018

1 reference

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6 July 2018

1 reference

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Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans

6 July 2018

1 reference

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No association between insulin gene variation and adult metabolic phenotypes in a large Finnish birth cohort

6 July 2018

1 reference

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6 July 2018

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Insulator and silencer sequences in the imprinted region of human chromosome 11p15.5.

6 July 2018

1 reference

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Transposable elements: targets for early nutritional effects on epigenetic gene regulation

6 July 2018

1 reference

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6 July 2018

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MethPrimer: designing primers for methylation PCRs

6 July 2018

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6 July 2018

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Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer

6 July 2018

1 reference

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A conserved structural element in horse and mouse IGF2 genes binds a methylation sensitive factor

6 July 2018

1 reference

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Identification of genetic elements that autonomously determine DNA methylation states.

6 July 2018

1 reference

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An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Imprinting of IGF2 P0 transcript and novel alternatively spliced INS-IGF2 isoforms show differences between mouse and human.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

The culture of zygotes to the blastocyst stage changes the postnatal expression of an epigentically labile allele, agouti viable yellow, in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Paternal allele of IGF2 gene haplotype CTG is associated with fetal and placental growth in Japanese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

The insulin gene variable number of tandem repeat: associations and interactions with childhood body fat mass and insulin secretion in normal children.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

INS VNTR class genotype and the function of isolated human islets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Challenges and Novel Approaches in the Epidemiological Study of Early Life Influences on Later Disease

21 January 2018

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Epigenetics as a unifying principle in the aetiology of complex traits and diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Association between small for gestational age and paternally inherited 5' insulin haplotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Associations of IGF2 ApaI RFLP and INS VNTR class I allele size with obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Cohort Profile: The Dutch Hunger Winter Families Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037933

Hypermethylation of the IGF2 differentially methylated region 2 is a specific event in insulinomas leading to loss-of-imprinting and overexpression

21 January 2018

1 reference

12 December 2020

Insulin VNTR and IGF-1 promoter region polymorphisms are not associated with body composition in early childhood: the generation R study.

1 reference

12 December 2020

Evidence that insulin is imprinted in the human yolk sac

1 reference

12 December 2020

Positive associations between single nucleotide polymorphisms in the IGF2 gene region and body mass index in adult males

1 reference

12 December 2020

Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2

1 reference

12 December 2020

Loss of IGF2 imprinting: a potential marker of colorectal cancer risk

1 reference

12 December 2020

Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus

1 reference

12 December 2020

Association between paternally inherited haplotypes upstream of the insulin gene and umbilical cord IGF-II levels

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0037933

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22666415%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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3 February 2020

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