Bcl-2 family proteins as targets for anticancer drug design (Q34293584)

1 August 2017

1 reference

title

Bcl-2 family proteins as targets for anticancer drug design (English)

1 reference

1 August 2017

0 references

Huang Z

1

1 reference

PubMed ID

11426648

1 August 2017

language of work or name

English

0 references

publication date

1 December 2000

1 reference

1 August 2017

1 reference

1 August 2017

19

1 reference

1 August 2017

56

1 reference

1 August 2017

6627-6631

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204087

1 August 2017

0 references

cites work

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

BCL-2 family: regulators of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Solution structure of BID, an intracellular amplifier of apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Structural chemistry and therapeutic intervention of protein-protein interactions in immune response, human immunodeficiency virus entry, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Bcl-2 and the regulation of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Apoptosis in the pathogenesis and treatment of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

Regulation of apoptosis by BH3 domains in a cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

7 January 2021

Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

7 January 2021

bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

7 January 2021

Structural factors of antimycin A molecule required for inhibitory action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

7 January 2021

Novel antitumor antibiotics, tetrocarcins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

7 January 2021

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204087

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1204087

1 reference

PubMed ID

11426648

Dimensions Publication ID

1 August 2017

0 references

1 reference

PubMed ID

11426648