Engineered biosynthesis of aklanonic acid analogues (Q34293749)

1 August 2017

title

Engineered biosynthesis of aklanonic acid analogues (English)

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1 August 2017

2

Chaitan Khosla

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1 August 2017

Taek Soon Lee

1

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1 August 2017

Yi Tang

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

1 September 2005

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1 August 2017

number of pages

9

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Journal of the American Chemical Society

inferred from page(s)

published in

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1 August 2017

volume

127

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1 August 2017

issue

35

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1 August 2017

page(s)

12254-12262

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Engineered biosynthesis of regioselectively modified aromatic polyketides using bimodular polyketide synthases

1 August 2017

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Anthracyclines: selected new developments

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6 July 2018

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6 July 2018

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6 July 2018

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The Streptomyces peucetius dpsC gene determines the choice of starter unit in biosynthesis of the daunorubicin polyketide.

6 July 2018

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6 July 2018

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Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes

6 July 2018

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6 July 2018

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The Streptomyces peucetius dpsY and dnrX genes govern early and late steps of daunorubicin and doxorubicin biosynthesis

6 July 2018

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Production of the antitumor drug epirubicin (4'-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius

6 July 2018

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6 July 2018

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Engineered biosynthesis of novel polyketides

6 July 2018

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Influence of structural modifications at the 3' and 4' positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance.

6 July 2018

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Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus

6 July 2018

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Engineered biosynthesis of novel polyketides: stereochemical course of two reactions catalyzed by a polyketide synthase

6 July 2018

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Analysis of clustered genes encoding both early and late steps in daunomycin biosynthesis by Streptomyces sp. strain C5.

6 July 2018

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6 July 2018

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A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermecti

6 July 2018

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Functional characterization and transcriptional analysis of a gene cluster governing early and late steps in daunorubicin biosynthesis in Streptomyces peucetius

6 July 2018

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Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosynthesis enzyme and a glycosyl transferase involved in daunorubicin biosynthesis

6 July 2018

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Isolation and chemical structure of aklanonic acid, an early intermediate in the biosynthesis of anthracyclines

6 July 2018

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Novel anthracycline analogs

6 July 2018

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Molecular genetics of polyketides and its comparison to fatty acid biosynthesis

6 July 2018

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Spore colour in Streptomyces coelicolor A3(2) involves the developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics

6 July 2018

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Analysis of a polyketide synthesis-encoding gene cluster of Streptomyces curacoi

6 July 2018

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AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A.

6 July 2018

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Studies on a Second and Third Ring Cyclization in Anthracycline Biosynthesis

28 October 2018

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In vitro reconstitution and analysis of the chain initiating enzymes of the R1128 polyketide synthase

28 October 2018

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Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.

28 October 2018

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Domain analysis of the molecular recognition features of aromatic polyketide synthase subunits

28 October 2018

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R1128 substances, novel non-steroidal estrogen-receptor antagonists produced by a Streptomyces. I. Taxonomy, fermentation, isolation and biological properties.

28 October 2018

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Cloning and disruption of a fragment of Streptomyces halstedii DNA involved in the biosynthesis of a spore pigment

28 October 2018

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Daunorubicinol, a major metabolite of daunorubicin: isolation from human urine and enzymatic reactions

28 October 2018

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From the pigments of the actinomycetes to third generation antitumor anthracyclines

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Preparation and biological evaluation of 4-O-demethyldaunorubicin (carminomycin I) and of its 13-dihydro derivative

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Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV40 DNA: relationship with DNA binding affinity and cytotoxicity

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7-(Aminoethyl) ether and thioether of daunomycinone

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Isolation and chemical structure of aklanonic acid, an early intermediate in the biosynthesis of anthracyclines.

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.38.1034

The Streptomyces peucetius dpsC Gene Determines the Choice of Starter Unit in Biosynthesis of the Daunorubicin Polyketide

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.181.15.4690-4695.1999

The Streptomyces peucetius dpsY anddnrX Genes Govern Early and Late Steps of Daunorubicin and Doxorubicin Biosynthesis

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.180.9.2379-2386.1998

Identifiers

DOI

10.1021/JA051429Z

1 reference

1 August 2017

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1 August 2017

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