The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies (Q34295964)

1 August 2017

1 reference

title

The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies (English)

1 reference

1 August 2017

0 references

1 reference

Heim C

1

1 reference

PubMed ID

11430844

1 August 2017

Nemeroff CB

series ordinal

2

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PubMed ID

11430844

1 August 2017

language of work or name

English

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publication date

1 June 2001

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1 August 2017

Biological Psychiatry

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1 August 2017

49

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1 August 2017

1023-1039

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1 August 2017

12

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Environmental stress and psychiatric illness

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The role of corticotropin-releasing factor in depression and anxiety disorders.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Cerebrospinal fluid neuropeptides in mood disorder and dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Corticotropin-releasing hormone challenge in prepubertal major depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The antidepressants fluoxetine, idazoxan and phenelzine alter corticotropin-releasing hormone and tyrosine hydroxylase mRNA levels in rat brain: therapeutic implications

7 January 2021

1 reference

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Long-term antidepressant administration alters corticotropin-releasing hormone, tyrosine hydroxylase, and mineralocorticoid receptor gene expression in rat brain. Therapeutic implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Early parental loss and development of adult psychopathology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Hippocampal volume reduction in major depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Psychological and neuroendocrinological sequelae of early social deprivation in institutionalized children in Romania

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Alterations in corticotropin-releasing factor-like immunoreactivity in discrete rat brain regions after acute and chronic stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Physical violence during pregnancy: maternal complications and birth outcomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Persistent elevations of cerebrospinal fluid concentrations of corticotropin-releasing factor in adult nonhuman primates exposed to early-life stressors: implications for the pathophysiology of mood and anxiety disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Growth hormone response to clonidine in adversely reared young adult primates: relationship to serial cerebrospinal fluid corticotropin-releasing factor concentrations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Prenatal stress increases corticotropin-releasing factor (CRF) content and release in rat amygdala minces

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Dysfunction in the neural circuitry of emotion regulation--a possible prelude to violence.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

A.E. Bennett Research Award. Developmental traumatology. Part I: Biological stress systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Association of fluoxetine treatment with reductions in CSF concentrations of corticotropin-releasing hormone and arginine vasopressin in patients with major depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

A.E. Bennett Research Award. Developmental traumatology. Part II: Brain development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

N-Acetylaspartate concentration in the anterior cingulate of maltreated children and adolescents with PTSD

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Urinary catecholamine excretion in sexually abused girls

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Stress-induced alterations in corticotropin-releasing hormone and vasopressin gene expression in the paraventricular nucleus during ontogeny

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Response to oCRH in depressed and nondepressed adolescents: does gender make a difference?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Prefrontal cortical-amygdalar metabolism in major depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Rearing experiences and stress-induced plasma cortisol as early risk factors for excessive alcohol consumption in nonhuman primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Psychiatric diagnoses of maltreated children: preliminary findings

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Age and gender differences in children's and adolescents' adaptation to sexual abuse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Neural mechanisms involved in the corticosteroid feedback effects on the hypothalamo-pituitary-adrenocortical axis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Preventive intervention for maltreated preschool children: impact on children's behavior, neuroendocrine activity, and foster parent functioning.

7 January 2021

1 reference

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The role of corticotropin-releasing factor--norepinephrine systems in mediating the effects of early experience on the development of behavioral and endocrine responses to stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Neuroendocrine responses to psychological stress in adolescents with anxiety disorder.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Child abuse and neglect and the brain--a review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Basal cortisol, dexamethasone suppression of cortisol, and MHPG in adolescents after the 1988 earthquake in Armenia

7 January 2021

1 reference

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Risk for psychopathology in the children of depressed mothers: a developmental model for understanding mechanisms of transmission

7 January 2021

1 reference

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Pregnancy intendedness and physical abuse around the time of pregnancy: findings from the pregnancy risk assessment monitoring system, 1996-1997. PRAMS Working Group. Pregnancy Risk Assessment Monitoring System

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The impact of early adverse experiences on brain systems involved in the pathophysiology of anxiety and affective disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Altered pituitary-adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Selective serotonin reuptake inhibitors in post-traumatic stress disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Serotonergic function in social phobia: comparison to normal control and obsessive-compulsive disorder subjects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Prenatal exposure to famine and brain morphology in schizophrenia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Depressive disorders in maltreated children

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The corticotropin-releasing hormone challenge in depressed abused, depressed nonabused, and normal control children.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Serotonergic functioning in depressed abused children: clinical and familial correlates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Effects of early adverse experiences on brain structure and function: clinical implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Effects of the CRF(1) receptor antagonist, CP 154,526, in the separation-induced vocalization anxiolytic test in rat pups.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Childhood sexual abuse and adult psychiatric and substance use disorders in women: an epidemiological and cotwin control analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Childhood parental loss and adult psychopathology in women. A twin study perspective

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The prediction of major depression in women: toward an integrated etiologic model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Effects of Corticotropin-Releasing Factor on Neuronal Activity in the Serotonergic Dorsal Raphe Nucleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Emotion circuits in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Intra-amygdala injections of corticotropin releasing factor facilitate inhibitory avoidance learning and reduce exploratory behavior in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Influence of neonatal rearing conditions on stress-induced adrenocorticotropin responses and norepinepherine release in the hypothalamic paraventricular nucleus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Maternal care, hippocampal synaptogenesis and cognitive development in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Childhood attachment and loss experiences affect adult cardiovascular and cortisol function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Increased 24-hour urinary cortisol excretion in patients with post-traumatic stress disorder and patients with major depression, but not in patients with fibromyalgia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The effects of family and community violence on children

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Protective and damaging effects of stress mediators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Abuse during pregnancy: associations with maternal health and infant birth weight.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Relationship of obstetric complications and differences in size of brain structures in monozygotic twin pairs discordant for schizophrenia.

7 January 2021

1 reference

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Adoption reverses the long-term impairment in glucocorticoid feedback induced by prenatal stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Chronic imipramine is associated with diminished hypothalamic-pituitary-adrenal axis responsivity in healthy humans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Major stressful life events in relation to prevalence of undetected type 2 diabetes: the Hoorn Study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The long-term impact of the physical, emotional, and sexual abuse of children: a community study.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The preeminent role of early untoward experience on vulnerability to major psychiatric disorders: the nature-nurture controversy revisited and soon to be resolved

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Neurobiology of posttraumatic stress disorder.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

A prospective study of daily stressors and symptomatology in schizophrenic patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Post-traumatic stress disorder in physically abused adolescents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Maternal separation in neonatal rats elicits activation of the hypothalamic-pituitary-adrenocortical axis: a putative role for corticotropin-releasing factor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Neuroendocrine response to fenfluramine challenge in boys. Associations with aggressive behavior and adverse rearing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Effects of corticotropin-releasing factor on brain serotonergic activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer's disease and depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Serotonergic blunting to meta-chlorophenylpiperazine (m-CPP) highly correlates with sustained childhood abuse in impulsive and autoaggressive female borderline patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Adverse early experiences affect noradrenergic and serotonergic functioning in adult primates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuse

7 January 2021

1 reference

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Yohimbine challenge in children with anxiety disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Amygdala core nuclei volumes are decreased in recurrent major depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Hippocampal atrophy in recurrent major depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Chronic administration of the triazolobenzodiazepine alprazolam produces opposite effects on corticotropin-releasing factor and urocortin neuronal systems.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Single photon emission computed tomography of the brain with Tc-99m HMPAO during sumatriptan challenge in obsessive-compulsive disorder: investigating the functional role of the serotonin auto-receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Childhood physical and sexual abuse in patients with anxiety disorders and in a community sample

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Hippocampal volume in women victimized by childhood sexual abuse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Enhanced dexamethasone suppression of plasma cortisol in adult women traumatized by childhood sexual abuse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Prenatal stress alters brain catecholaminergic activity and potentiates stress-induced behavior in adult rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Changes in daily hassles and life events and the relationship with coronary heart disease risk factors: a 2-year longitudinal study in 27-29-year-old males and females

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Early vs. late maternal deprivation differentially alters the endocrine and hypothalamic responses to stress.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Effect of desipramine on cerebrospinal fluid concentrations of corticotropin-releasing factor in human subjects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

The role of stress and trauma in rheumatoid arthritis and systemic lupus erythematosus

7 January 2021

1 reference

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Effects of prenatal stress on defensive withdrawal behavior and corticotropin releasing factor systems in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Depression and anxiety: role of the locus coeruleus and corticotropin-releasing factor.

7 January 2021

1 reference

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Dexamethasone suppression test and depressive symptoms in bereaved children: a preliminary report.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropin-releasing hormone

7 January 2021

1 reference

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The Brown Norway rat displays enhanced stress-induced ACTH reactivity at day 18 after 24-h maternal deprivation at day 3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Hormonal evidence for altered responsiveness to social stress in major depression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

Long-term behavioral and neuroendocrine adaptations to adverse early experience

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Psychiatric history and stress: predictors of severity of unipolar depression

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Psychophysiologic assessment of women with posttraumatic stress disorder resulting from childhood sexual abuse.

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3223%2801%2901157-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-3223(01)01157-X

1 reference

1 August 2017

1 reference

PubMed ID

11430844