After TGN1412: recent developments in cytokine release assays. (Q34299057)

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12 February 2020

title

After TGN1412: recent developments in cytokine release assays (English)

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1

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author name string

D Eastwood

series ordinal

2

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12 February 2020

S Poole

series ordinal

3

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R Thorpe

series ordinal

4

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12 February 2020

publication date

11 September 2012

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Journal of Immunotoxicology

12 February 2020

published in

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12 February 2020

volume

10

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12 February 2020

issue

1

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12 February 2020

page(s)

75-82

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Were monocytes responsible for initiating the cytokine storm in the TGN1412 clinical trial tragedy?

12 February 2020

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6 July 2018

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6 July 2018

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Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.

6 July 2018

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CCR7 expression and memory T cell diversity in humans

6 July 2018

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

6 July 2018

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Cytokine-release syndrome in patients with B-cell chronic lymphocytic leukemia and high lymphocyte counts after treatment with an anti-CD20 monoclonal antibody (rituximab, IDEC-C2B8).

6 July 2018

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A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

6 July 2018

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Three-dimensional segregation of supramolecular activation clusters in T cells

6 July 2018

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Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes

6 July 2018

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Mechanism of first-dose cytokine-release syndrome by CAMPATH 1-H: involvement of CD16 (FcgammaRIII) and CD11a/CD18 (LFA-1) on NK cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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CD28 delivers a costimulatory signal involved in antigen-specific IL-2 production by human T cells.

6 July 2018

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6 July 2018

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21 January 2018

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21 January 2018

Lessons from TGN1412.

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21 January 2018

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21 January 2018

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Preculture of PBMCs at high cell density increases sensitivity of T-cell responses, revealing cytokine release by CD28 superagonist TGN1412.

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21 January 2018

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21 January 2018

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28 October 2018

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12 December 2020

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12 December 2020

Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412

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12 December 2020

Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

CD28-mediated induction of proliferation in resting T cells in vitro and in vivo without engagement of the T cell receptor: evidence for functionally distinct forms of CD28

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12 December 2020

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Identifiers

DOI

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