Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease. (Q34299310)

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English	Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease.	scientific article

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14 February 2020

Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease (English)

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14 February 2020

Alzheimer's disease

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cerebral amyloid angiopathy

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9

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10

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author name string

Terry L Lewis

1

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14 February 2020

Dongfeng Cao

2

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14 February 2020

Hailin Lu

3

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14 February 2020

Robert A Mans

4

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14 February 2020

Yan Ru Su

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14 February 2020

Lisa Jungbauer

6

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14 February 2020

MacRae F Linton

7

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14 February 2020

Sergio Fazio

8

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16 September 2010

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14 February 2020

Journal of Biological Chemistry

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285

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47

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36958-36968

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14 February 2020

Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice

1 reference

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Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation

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Mechanisms underlying inflammation in neurodegeneration

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Neuroinflammation – An Early Event in Both the History and Pathogenesis of Alzheimer’s Disease

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Obesity and Alzheimer's disease: a link between body weight and cognitive function in old age.

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Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses

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Physical activity, diet, and risk of Alzheimer disease

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6 July 2018

Oral apolipoprotein A-I mimetic peptide improves cognitive function and reduces amyloid burden in a mouse model of Alzheimer's disease

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The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged

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6 July 2018

Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity

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Cardiovascular risk factors and dementia

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Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

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Low HDL cholesterol is a risk factor for deficit and decline in memory in midlife: the Whitehall II study

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Lentiviral transduction of apoAI into hematopoietic progenitor cells and macrophages: applications to cell therapy of atherosclerosis

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Molecular regulation of macrophage reverse cholesterol transport

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6 July 2018

Invited commentary: lipoproteins and dementia - is it the apolipoprotein A-I?

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APOA1 polymorphism influences risk for early-onset nonfamiliar AD

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The double jeopardy of HDL.

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HDL as a target in the treatment of atherosclerotic cardiovascular disease

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6 July 2018

Apolipoprotein E isoforms and apolipoprotein AI protect from amyloid precursor protein carboxy terminal fragment-associated cytotoxicity

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Antiinflammatory properties of HDL.

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6 July 2018

ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis

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6 July 2018

Relation of plasma lipids to Alzheimer disease and vascular dementia

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Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

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Association of aortic atherosclerosis with cerebral beta-amyloidosis and learning deficits in a mouse model of Alzheimer's disease.

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Paraoxonase and atherosclerosis

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Apolipoprotein A-I directly interacts with amyloid precursor protein and inhibits A beta aggregation and toxicity

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Cholesterol metabolism in the brain

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Differences in the Abeta40/Abeta42 ratio associated with cerebrospinal fluid lipoproteins as a function of apolipoprotein E genotype.

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Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease.

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Retrovirus-mediated expression of apolipoprotein A-I in the macrophage protects against atherosclerosis in vivo

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21 January 2018

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21 January 2018

An apolipoprotein A-I gene promoter polymorphism associated with cognitive decline, but not with Alzheimer's disease

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21 January 2018

The relation between apolipoprotein A-I and dementia: the Honolulu-Asia aging study

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21 January 2018

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21 January 2018

Simvastatin enhances learning and memory independent of amyloid load in mice.

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21 January 2018

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

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21 January 2018

Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia

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21 January 2018

Double belt structure of discoidal high density lipoproteins: molecular basis for size heterogeneity

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21 January 2018

Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain.

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21 January 2018

Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease.

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21 January 2018

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Plasma HDL levels highly correlate with cognitive function in exceptional longevity

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21 January 2018

A genotype of exceptional longevity is associated with preservation of cognitive function.

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21 January 2018

HDL: close to our memories?

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D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet

1 reference

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21 January 2018

Expression of human apolipoprotein A-I/C-III/A-IV gene cluster in mice induces hyperlipidemia but reduces atherogenesis

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum Paraoxonase Activity, Concentration, and Phenotype Distribution in Diabetes Mellitus and Its Relationship to Serum Lipids and Lipoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

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Marked decrease of plasma apolipoprotein AI and AII in Japanese patients with late-onset non-familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain expression of apolipoproteins E, J, and A-I in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A-I in the human artery wall with the progression of atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

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Alzheimer's amyloid beta interaction with normal human plasma high density lipoprotein: association with apolipoprotein and lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/20847045

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.127829

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20847045%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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