Domestic-animal genomics: deciphering the genetics of complex traits (Q34299462)

1 August 2017

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title

Domestic-animal genomics: deciphering the genetics of complex traits (English)

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1 August 2017

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Leif Andersson

1

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1 August 2017

Michel Georges

series ordinal

2

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1 August 2017

publication date

1 March 2004

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1 August 2017

published in

Nature Reviews Genetics

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1 August 2017

volume

5

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1 August 2017

issue

3

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1 August 2017

page(s)

202-212

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Complexities in the genetic dissection of quantitative trait loci

1 August 2017

cites work

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Finding genes that underlie complex traits

31 March 2020

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A vision for the future of genomics research

31 March 2020

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Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition

31 March 2020

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A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig.

31 March 2020

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Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content

31 March 2020

1 reference

Quantitative trait loci in Drosophila

31 March 2020

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Genetic dissection of phenotypic diversity in farm animals

31 March 2020

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Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice

31 March 2020

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A global search reveals epistatic interaction between QTL for early growth in the chicken

31 March 2020

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Genome-Wide Epistatic Interaction Analysis Reveals Complex Genetic Determinants of Circadian Behavior in Mice

31 March 2020

1 reference

Dissecting the architecture of a quantitative trait locus in yeast

31 March 2020

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Identification of a Mutation in Porcine Ryanodine Receptor Associated with Malignant Hyperthermia

31 March 2020

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Molecular basis for the dominant white phenotype in the domestic pig.

31 March 2020

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A missense mutation in the bovine MGF gene is associated with the roan phenotype in Belgian Blue and Shorthorn cattle

31 March 2020

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A mutation in PRKAG3 associated with excess glycogen content in pig skeletal muscle

31 March 2020

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A second mutant allele (V199I) at the PRKAG3 (RN) locus- I. Effect on technological meat quality of pork loin

31 March 2020

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A second mutant allele (V199I) at the PRKAG3 (RN) locus-II. Effect on colour characteristics of pork loin

31 March 2020

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CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

31 March 2020

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Experimental strategies for the genetic dissection of complex traits in animal models

31 March 2020

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The hitch-hiking effect of a favourable gene

31 March 2020

2 references

31 March 2020

inferred from DOI database lookup

7 January 2021

based on heuristic

Genealogies of mouse inbred strains

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The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs

31 March 2020

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The dog genome: survey sequencing and comparative analysis

31 March 2020

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Unleashing the canine genome

31 March 2020

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A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog.

31 March 2020

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Placental mammal diversification and the Cretaceous-Tertiary boundary

31 March 2020

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Single nucleotide polymorphism (SNP) discovery in porcine expressed genes

31 March 2020

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The mosaic structure of variation in the laboratory mouse genome

31 March 2020

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The International HapMap Project

31 March 2020

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Extensive genome-wide linkage disequilibrium in cattle

31 March 2020

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DNA markers reveal the complexity of livestock domestication

31 March 2020

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Genetical genomics: the added value from segregation.

31 March 2020

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Genetics of gene expression surveyed in maize, mouse and man

31 March 2020

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Review of proteomics with applications to genetic epidemiology

31 March 2020

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Sequencing the chimpanzee genome: insights into human evolution and disease

31 March 2020

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Molecular evolution of FOXP2, a gene involved in speech and language

31 March 2020

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Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios

31 March 2020

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Initial sequencing and comparative analysis of the mouse genome

31 March 2020

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Comparative analyses of multi-species sequences from targeted genomic regions

31 March 2020

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Identification and characterization of multi-species conserved sequences

31 March 2020

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Principles for the buffering of genetic variation

31 March 2020

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

31 March 2020

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Epigenetic inheritance at the agouti locus in the mouse

31 March 2020

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Chromosomal inheritance of epigenetic states in fission yeast during mitosis and meiosis

31 March 2020

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The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis

31 March 2020

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Evidence for an epigenetic mechanism by which Hsp90 acts as a capacitor for morphological evolution.

31 March 2020

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An epigenetic mutation responsible for natural variation in floral symmetry

31 March 2020

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Epi-alleles in plants: inheritance of epigenetic information over generations

31 March 2020

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DNA methylation and epigenetic inheritance in plants and filamentous fungi

31 March 2020

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A paternally expressed QTL affecting skeletal and cardiac muscle mass in pigs maps to the IGF2 locus

31 March 2020

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An imprinted QTL with major effect on muscle mass and fat deposition maps to the IGF2 locus in pigs

31 March 2020

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A phylogenetic study of the origin of the domestic pig estimated from the near-complete mtDNA genome

31 March 2020

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A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle

31 March 2020

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Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double-muscling in cattle

31 March 2020

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Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle

31 March 2020

2 references

31 March 2020

inferred from DOI database lookup

7 January 2021

based on heuristic

Double muscling in cattle due to mutations in the myostatin gene

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The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination

31 March 2020

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A nonsense mutation in the FMO3 gene underlies fishy off-flavor in cow's milk

31 March 2020

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Autosomal albino chicken mutation (ca/ca) deletes hexanucleotide (-deltaGACTGG817) at a copper-binding site of the tyrosinase gene

31 March 2020

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Melanocortin 1-receptor (MC1R) mutations are associated with plumage colour in chicken

31 March 2020

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The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

31 March 2020

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MC1R Studies in Dogs With Melanistic Mask or Brindle Patterns

31 March 2020

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A 11.7-kb deletion triggers intersexuality and polledness in goats

31 March 2020

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A missense mutation in the gene for melanocyte-stimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses

31 March 2020

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Mutations in the agouti (ASIP), the extension (MC1R), and the brown (TYRP1) loci and their association to coat color phenotypes in horses (Equus caballus).

31 March 2020

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A mutation in the MATP gene causes the cream coat colour in the horse

31 March 2020

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Endothelin receptor B polymorphism associated with lethal white foal syndrome in horses

31 March 2020

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A missense mutation in the endothelin-B receptor gene is associated with Lethal White Foal Syndrome: an equine version of Hirschsprung disease

31 March 2020

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A dinucleotide mutation in the endothelin-B receptor gene is associated with lethal white foal syndrome (LWFS); a horse variant of Hirschsprung disease

31 March 2020

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Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor

31 March 2020

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A large duplication associated with dominant white color in pigs originated by homologous recombination between LINE elements flanking KIT.

31 March 2020

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A DNA polymorphism influencing alpha(1,2)fucosyltransferase activity of the pig FUT1 enzyme determines susceptibility of small intestinal epithelium to Escherichia coli F18 adhesion.

31 March 2020

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Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner

31 March 2020

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Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewes

31 March 2020

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Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals.

31 March 2020

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The callipyge mutation enhances the expression of coregulated imprinted genes in cis without affecting their imprinting status

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRG1294

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Dimensions Publication ID

1 August 2017

1002924872

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