Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts. (Q34300281)

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English	Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.	scientific article

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24 November 2019

Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts (English)

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24 November 2019

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Susan S Wallace

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24 November 2019

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Scott D Kathe

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24 November 2019

Guang-Ping Shen

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21 February 2004

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24 November 2019

Journal of Biological Chemistry

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24 November 2019

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24 November 2019

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24 November 2019

18511-18520

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24 November 2019

Mechanisms of transcription-coupled DNA repair

1 reference

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Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome

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21 January 2018

Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G

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21 January 2018

Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome

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21 January 2018

Initiation of base excision repair: glycosylase mechanisms and structures

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Quality control by DNA repair

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21 January 2018

Transcriptional mutagenesis induced by uracil and 8-oxoguanine in Escherichia coli.

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21 January 2018

Repair of 8-oxoG is slower in endogenous nuclear genes than in mitochondrial DNA and is without strand bias.

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Repair of oxidative damage in nuclear DNA sequences with different transcriptional activities.

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21 January 2018

Gene-specific repair of gamma-ray-induced DNA strand breaks in colon cancer cells: no coupling to transcription and no removal from the mitochondrial genome.

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21 January 2018

Transcription-coupled DNA repair is genomic context-dependent

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Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

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21 January 2018

Molecular mechanism of transcription-repair coupling.

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E. coli Transcription repair coupling factor (Mfd protein) rescues arrested complexes by promoting forward translocation

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Biological consequences of free radical-damaged DNA bases.

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Effects on sister chromatid exchange frequency of aldehyde dehydrogenase 2 genotype and smoking in vinyl chloride workers.

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Oxidative DNA lesions as blocks to in vitro transcription by phage T7 RNA polymerase

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21 January 2018

Effect of thymine glycol on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II

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21 January 2018

Effects of nonbulky DNA base damages on Escherichia coli RNA polymerase-mediated elongation and promoter clearance

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21 January 2018

Effects of endogenous DNA base lesions on transcription elongation by mammalian RNA polymerase II. Implications for transcription-coupled DNA repair and transcriptional mutagenesis.

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21 January 2018

Effects of abasic sites and DNA single-strand breaks on prokaryotic RNA polymerases

1 reference

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21 January 2018

T7 RNA polymerase bypass of large gaps on the template strand reveals a critical role of the nontemplate strand in elongation

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21 January 2018

Template strand gap bypass is a general property of prokaryotic RNA polymerases: implications for elongation mechanisms.

1 reference

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21 January 2018

The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

1 reference

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21 January 2018

The Cockayne syndrome B protein, involved in transcription-coupled DNA repair, resides in an RNA polymerase II-containing complex

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21 January 2018

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

1 reference

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21 January 2018

Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein

1 reference

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21 January 2018

Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA template

1 reference

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21 January 2018

Escherichia coli endonuclease VIII: cloning, sequencing, and overexpression of the nei structural gene and characterization of nei and nei nth mutants

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21 January 2018

The mechanisms of action of E. coli endonuclease III and T4 UV endonuclease (endonuclease V) at AP sites

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21 January 2018

The multiple activities of Escherichia coli endonuclease IV and the extreme lability of 5'-terminal base-free deoxyribose 5-phosphates

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21 January 2018

Mechanism of DNA strand nicking at apurinic/apyrimidinic sites by Escherichia coli [formamidopyrimidine]DNA glycosylase

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21 January 2018

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

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21 January 2018

The enigma of endonuclease VIII.

1 reference

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Escherichia coli RNA and DNA polymerase bypass of dihydrouracil: mutagenic potential via transcription and replication

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21 January 2018

XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair

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Induction, repair and biological relevance of radiation-induced DNA lesions in eukaryotic cells

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Transcription elongation factor SII.

1 reference

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21 January 2018

Requirement of yeast RAD2, a homolog of human XPG gene, for efficient RNA polymerase II transcription. implications for Cockayne syndrome

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21 January 2018

XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

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Cockayne's Syndrome Fibroblasts Have Increased Sensitivity to Ultraviolet Light But Normal Rates of Unscheduled DNA Synthesis

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Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions

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ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor.

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Cockayne syndrome group B protein enhances elongation by RNA polymerase II

1 reference

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Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

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The CBP co-activator is a histone acetyltransferase

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The transcriptional coactivators p300 and CBP are histone acetyltransferases

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Accessing DNA damage in chromatin: insights from transcription

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21 January 2018

Repair of radiation-induced DNA strand breaks does not occur preferentially in transcriptionally active DNA

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Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions

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Transcription bypass or blockage at single-strand breaks on the DNA template strand: effect of different 3' and 5' flanking groups on the T7 RNA polymerase elongation complex

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Genetic complementation groups in Cockayne syndrome

1 reference

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10.1074/JBC.M313598200

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978042%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978042%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

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