A kinetic clutch governs religation by type IB topoisomerases and determines camptothecin sensitivity (Q34300595)

1 August 2017

title

A kinetic clutch governs religation by type IB topoisomerases and determines camptothecin sensitivity (English)

1 reference

1 August 2017

3

Yves Pommier

1 reference

1 August 2017

Yeonee Seol

1

1 reference

1 August 2017

Hongliang Zhang

series ordinal

2

1 reference

1 August 2017

Keir C Neuman

series ordinal

4

1 reference

1 August 2017

language of work or name

English

0 references

publication date

18 September 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

109

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1 August 2017

issue

40

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1 August 2017

page(s)

16125-16130

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The importance of being supercoiled: how DNA mechanics regulate dynamic processes

1 August 2017

cites work

1 reference

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Magnetic tweezers for single-molecule manipulation

6 July 2018

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The geometry of DNA supercoils modulates the DNA cleavage activity of human topoisomerase I

6 July 2018

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6 July 2018

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Free energy calculations reveal rotating-ratchet mechanism for DNA supercoil relaxation by topoisomerase IB and its inhibition

6 July 2018

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DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

6 July 2018

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Single-molecule measurements of DNA topology and topoisomerases.

6 July 2018

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Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

6 July 2018

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Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA.

6 July 2018

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6 July 2018

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DNA topoisomerases: harnessing and constraining energy to govern chromosome topology

6 July 2018

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Role of a tryptophan anchor in human topoisomerase I structure, function and inhibition

6 July 2018

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6 July 2018

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Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal

6 July 2018

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Topoisomerase V relaxes supercoiled DNA by a constrained swiveling mechanism

6 July 2018

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The open state of human topoisomerase I as probed by molecular dynamics simulation

6 July 2018

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Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxation

6 July 2018

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6 July 2018

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Synthesis and mechanism of action studies of a series of norindenoisoquinoline topoisomerase I poisons reveal an inhibitor with a flipped orientation in the ternary DNA-enzyme-inhibitor complex as determined by X-ray crystallographic analysis

6 July 2018

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Human DNA topoisomerase I: relaxation, roles, and damage control

6 July 2018

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Role of the linker domain and the 203-214 N-terminal residues in the human topoisomerase I DNA complex dynamics.

6 July 2018

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Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

6 July 2018

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Cellular roles of dna topoisomerases: a molecular perspective

6 July 2018

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6 July 2018

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DNA topoisomerases: structure, function, and mechanism

6 July 2018

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A model for the mechanism of human topoisomerase I

6 July 2018

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Reconstitution of human topoisomerase I by fragment complementation

6 July 2018

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Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions

6 July 2018

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6 July 2018

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Mechanism of mitochondrial DNA replication in mouse L-cells: Introduction of superhelical turns into newly replicated molecules

6 July 2018

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Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

6 July 2018

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Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding

21 January 2018

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Torque and dynamics of linking number relaxation in stretched supercoiled DNA.

21 January 2018

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21 January 2018

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Domains of human topoisomerase I and associated functions.

21 January 2018

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Antitumour drugs impede DNA uncoiling by topoisomerase I

28 October 2018

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Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22991469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Single-molecule measurements of topoisomerase activity with magnetic tweezers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22991469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1206480109

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference