Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage (Q34305465)

1 August 2017

title

Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage (English)

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1 August 2017

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Leishmania donovani

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Amit Kumar Singh

1

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1 August 2017

Chaitali Mukhopadhyay

2

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1 August 2017

Sudipta Biswas

3

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1 August 2017

Vandana Kumari Singh

4

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1 August 2017

Chinmay K Mukhopadhyay

5

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1 August 2017

language of work or name

English

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publication date

12 June 2012

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

6

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1 August 2017

page(s)

e38489

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Creative Commons Attribution 4.0 International

1 August 2017

copyright license

start time

12 June 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63.

6 July 2018

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Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens

6 July 2018

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Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling

6 July 2018

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Interdependence of hypoxic and innate immune responses

6 July 2018

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An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.

6 July 2018

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Oxygen sensors at the crossroad of metabolism

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Oxygen-independent stabilization of hypoxia inducible factor (HIF)-1 during RSV infection

6 July 2018

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Plasminogen activator inhibitor-1 protects endothelial cells from FasL-mediated apoptosis

6 July 2018

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Leishmania donovani depletes labile iron pool to exploit iron uptake capacity of macrophage for its intracellular growth

6 July 2018

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NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

6 July 2018

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Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion

6 July 2018

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Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores

6 July 2018

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The Leishmania-macrophage interaction: a metabolic perspective

6 July 2018

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Hypoxia inducible factor (HIF) function in innate immunity and infection

6 July 2018

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6 July 2018

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Evaluation of HIF-1 inhibitors as anticancer agents

6 July 2018

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Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1 and Stimulates the Synthesis of Vascular Endothelial Growth Factor

6 July 2018

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Living in a phagolysosome; metabolism of Leishmania amastigotes

6 July 2018

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Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro

6 July 2018

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Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase

6 July 2018

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Role of host protein tyrosine phosphatase SHP-1 in Leishmania donovani-induced inhibition of nitric oxide production

6 July 2018

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A Leishmania amazonensis ZIP family iron transporter is essential for parasite replication within macrophage phagolysosomes.

6 July 2018

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Loss of VHL confers hypoxia-inducible factor (HIF)-dependent resistance to vesicular stomatitis virus: role of HIF in antiviral response

6 July 2018

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Leishmania promastigotes activate PI3K/Akt signalling to confer host cell resistance to apoptosis

6 July 2018

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Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB.

6 July 2018

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HIF-1alpha: a master regulator of innate host defenses?

6 July 2018

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Leishmania donovani activates nuclear transcription factor-kappaB in macrophages through reactive oxygen intermediates

6 July 2018

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

6 July 2018

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Genetic characterization of glucose transporter function in Leishmania mexicana

6 July 2018

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HIF-1alpha is essential for myeloid cell-mediated inflammation

6 July 2018

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Leishmania donovani suppresses activated protein 1 and NF-kappaB activation in host macrophages via ceramide generation: involvement of extracellular signal-regulated kinase

6 July 2018

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A conserved family of prolyl-4-hydroxylases that modify HIF

6 July 2018

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

6 July 2018

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

6 July 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

6 July 2018

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Role of hypoxia-inducible factor-1 in transcriptional activation of ceruloplasmin by iron deficiency

6 July 2018

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

6 July 2018

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

6 July 2018

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HIF-1alpha expression regulates the bactericidal capacity of phagocytes

6 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038489

Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha

21 January 2018

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Expression of hypoxia-inducible factor 1alpha in mononuclear phagocytes infected with Leishmania amazonensis

21 January 2018

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Activation of hypoxia-inducible factor-1 in bacillary angiomatosis: evidence for a role of hypoxia-inducible factor-1 in bacterial infections

21 January 2018

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The angiogenic and prognostic implications of VEGF, Ang-1, Ang-2, and MMP-9 for hepatocellular carcinoma with background of hepatitis B virus

21 January 2018

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HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite.

21 January 2018

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A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases

21 January 2018

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Human cutaneous lieshmania in a mouse macrophage line: propagation and isolation of intracellular parasites

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22701652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enhanced metabolism of Leishmania donovani amastigotes at acid pH: an adaptation for intracellular growth

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22701652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of hypoxia-inducible factor-1alpha in the cutaneous lesions of BALB/c mice infected with Leishmania amazonensis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22701652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0038489

1 reference

1 August 2017

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1 reference

1 August 2017

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