Virus-induced autoimmunity: epitope spreading to myelin autoepitopes in Theiler's virus infection of the central nervous system (Q34306662)

1 August 2017

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title

Virus-induced autoimmunity: epitope spreading to myelin autoepitopes in Theiler's virus infection of the central nervous system (English)

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infection of the central nervous system

1 August 2017

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author name string

Miller SD

1

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1 August 2017

Katz-Levy Y

2

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1 August 2017

Neville KL

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1 August 2017

Vanderlugt CL

4

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1 August 2017

1 January 2001

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Advances in Virus Research

1 August 2017

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1 August 2017

56

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1 August 2017

199-217

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T cells responsive to myelin basic protein in patients with multiple sclerosis

1 August 2017

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7 January 2021

Serum and cells from Theiler's virus-infected mice fail to injure myelinating cultures or to produce in vivo transfer of disease. The pathogenesis of Theiler's virus-induced demyelination appears to differ from that of EAE.

1 reference

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The role of CD8+T cells in the acute and chronic phases of Theiler's murine encephalomyelitis virus-induced disease in mice

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Theiler's virus persists in glial cells during demyelinating disease

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Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein

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Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. II. Survey of host immune responses and central nervous system virus titers in inbred mouse strains

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The Theiler's murine encephalomyelitis virus (TMEV) model for multiple sclerosis shows a strong influence of the murine equivalents of HLA-A, B, and C.

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Monocytes/macrophages isolated from the mouse central nervous system contain infectious Theiler's murine encephalomyelitis virus (TMEV).

1 reference

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Recurrent demyelination in chronic central nervous system infection produced by Theiler's murine encephalomyelitis virus

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7 January 2021

A genetic basis for familial aggregation in multiple sclerosis. Canadian Collaborative Study Group

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7 January 2021

Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity

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7 January 2021

Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease

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7 January 2021

Anergy in vivo: down-regulation of antigen-specific CD4+ Th1 but not Th2 cytokine responses

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7 January 2021

Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice

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7 January 2021

Temporal development of autoreactive Th1 responses and endogenous presentation of self myelin epitopes by central nervous system-resident APCs in Theiler's virus-infected mice

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Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

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Epidemiologic evidence for multiple sclerosis as an infection

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Cardiac persistence of cardioviral RNA detected by polymerase chain reaction in a murine model of dilated cardiomyopathy

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Demyelinative myelopathy in mice induced by the DA virus

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Persistent anti-myelin basic protein IgG antibody response in multiple sclerosis cerebrospinal fluid

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7 January 2021

Persistent Theiler's Murine Encephalomyelitis Virus Infection in Mice depends on Plaque Size

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7 January 2021

Theiler's Virus-Induced Demyelination: Prevention by Immunosuppression

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7 January 2021

Alterations in T cell antigen specificity and class II restriction during the course of chronic relapsing experimental allergic encephalomyelitis

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7 January 2021

Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis

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Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. III. Failure of neuroantigen-specific immune tolerance to affect the clinical course of demyelination

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7 January 2021

The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases

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Evolution of the T-cell repertoire during the course of experimental immune-mediated demyelinating diseases

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Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE

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7 January 2021

Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading

1 reference

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7 January 2021

BALB/c substrain differences in susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease

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T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

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Effects of irradiation on development of Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in genetically resistant mice

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T cell sensitization to proteolipid protein in myelin basic protein-induced relapsing experimental allergic encephalomyelitis

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7 January 2021

Split tolerance of Th1 and Th2 cells in tolerance to Theiler's murine encephalomyelitis virus

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7 January 2021

Persistent infection of oligodendrocytes in Theiler's virus‐induced encephalomyelitis

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7 January 2021

The effect of short-term and chronic immunosuppression on Theiler's virus demyelination

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The pathogenesis of postinfectious myocarditis

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Superantigens: bacterial and viral proteins that manipulate the immune system

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Autoreactive T and B cells responding to myelin proteolipid protein in multiple sclerosis and controls

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7 January 2021

SPONTANEOUS ENCEPHALOMYELITIS OF MICE, A NEW VIRUS DISEASE

1 reference

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7 January 2021

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

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7 January 2021

Diversity and plasticity of self recognition during the development of multiple sclerosis

1 reference

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7 January 2021

Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis

1 reference

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7 January 2021

The functional significance of epitope spreading and its regulation by co-stimulatory molecules

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Multiple sclerosis. More genes versus environment

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The effect of L3T4 T cell depletion on the pathogenesis of Theiler's murine encephalomyelitis virus infection in CBA mice

1 reference

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7 January 2021

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

1 reference

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7 January 2021

Characterization of and functional antigen presentation by central nervous system mononuclear cells from mice infected with Theiler's murine encephalomyelitis virus

1 reference

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7 January 2021

Identification of a major T-cell epitope within VP3 amino acid residues 24 to 37 of Theiler's virus in demyelination-susceptible SJL/J mice.

1 reference

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7 January 2021

10.1016/S0065-3527(01)56008-X

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DOI

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1 August 2017

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