Microglial interaction with beta-amyloid: implications for the pathogenesis of Alzheimer's disease (Q34309544)

1 August 2017

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title

Microglial interaction with beta-amyloid: implications for the pathogenesis of Alzheimer's disease (English)

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1 August 2017

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Bamberger ME

1

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PubMed ID

11455613

1 August 2017

Landreth GE

series ordinal

2

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1 August 2017

1 July 2001

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Microscopy Research and Technique

1 August 2017

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1 August 2017

54

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1 August 2017

59-70

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1 August 2017

2

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Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1 August 2017

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21 January 2018

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Brain microglia constitutively express beta-2 integrins.

21 January 2018

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Expression of intercellular adhesion molecule (ICAM)-1 by a subset of astrocytes in Alzheimer disease and some other degenerative neurological disorders.

21 January 2018

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Inflammation and Alzheimer's disease

21 January 2018

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Engagement of the scavenger receptor is not responsible for beta-amyloid stimulation of monocytes to a neurocytopathic state.

21 January 2018

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β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease

21 January 2018

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The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

21 January 2018

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Interleukin-6 and α-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices

21 January 2018

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Induction and regulation of interleukin-6 gene expression in rat astrocytes

21 January 2018

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beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease.

21 January 2018

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The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide

21 January 2018

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Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1

21 January 2018

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Complement-dependent proinflammatory properties of the Alzheimer's disease beta-peptide

21 January 2018

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The role of anti-inflammatory drugs in the prevention and treatment of Alzheimer's disease

21 January 2018

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Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins

21 January 2018

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Transforming growth factor-beta protects human neurons against beta-amyloid-induced injury.

21 January 2018

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Tumor necrosis factor-alpha and phorbol 12-myristate 13-acetate differentially modulate cytotoxic effect of nitric oxide generated by serum deprivation in neuronal PC12 cells.

21 January 2018

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Activation-induced association of a 145-kDa tyrosine-phosphorylated protein with Shc and Syk in B lymphocytes and macrophages

21 January 2018

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A 70-kDa protein facilitates interleukin-4 signal transduction in the absence of the common gamma receptor chain

21 January 2018

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

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Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease.

21 January 2018

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C-reactive protein-like immunoreactivity in the neurofibrillary tangles of Alzheimer's disease.

21 January 2018

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Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

21 January 2018

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Inhibiting the formation of classical C3-convertase on the Alzheimer's beta-amyloid peptide.

21 January 2018

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The role of complement in Alzheimer's disease pathology

21 January 2018

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A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.

21 January 2018

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Elevated circulating tumor necrosis factor levels in Alzheimer's disease

21 January 2018

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Expression of intercellular adhesion molecule 1 (ICAM-1) in Alzheimer's disease

21 January 2018

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Alpha 2-macroglobulin synthesis in interleukin-6-stimulated human neuronal (SH-SY5Y neuroblastoma) cells Potential significance for the processing of Alzheimer β-amyloid precursor protein

21 January 2018

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Thrombospondin modulates alpha v beta 3 function through integrin-associated protein

21 January 2018

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Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin

21 January 2018

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A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion

21 January 2018

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Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

21 January 2018

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Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

21 January 2018

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Synthetic Alzheimer amyloid beta/A4 peptides enhance production of complement C3 component by cultured microglial cells.

21 January 2018

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Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma

21 January 2018

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Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain

21 January 2018

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Elimination of the class A scavenger receptor does not affect amyloid plaque formation or neurodegeneration in transgenic mice expressing human amyloid protein precursors

21 January 2018

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Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

21 January 2018

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Identification of monocyte chemoattractant protein-1 in senile plaques and reactive microglia of Alzheimer's disease.

21 January 2018

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Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

21 January 2018

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Demonstration of CRP immunoreactivity in brains of Alzheimer's disease: immunohistochemical study using formic acid pretreatment of tissue sections.

21 January 2018

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Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures.

21 January 2018

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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

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Integrin-associated protein is a ligand for the P84 neural adhesion molecule

21 January 2018

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Microglia and Alzheimer's disease.

21 January 2018

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Activation of macrophages by Alzheimer beta amyloid peptide.

21 January 2018

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Interaction of Alzheimer beta-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-alpha

21 January 2018

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Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

21 January 2018

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Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

21 January 2018

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The role of protein tyrosine phosphorylation in integrin-mediated gene induction in monocytes

21 January 2018

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Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase.

21 January 2018

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Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding

21 January 2018

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Beta amyloid toxicity does not require RAGE protein

21 January 2018

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beta-Amyloid induces increased release of interleukin-1 beta from lipopolysaccharide-activated human monocytes

21 January 2018

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Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging.

21 January 2018

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Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptors

21 January 2018

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Immunoreactivity of CD45, a protein phosphotyrosine phosphatase, in Alzheimer's disease

21 January 2018

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The alpha5beta1 integrin mediates elimination of amyloid-beta peptide and protects against apoptosis

21 January 2018

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Complementary roles for scavenger receptor A and CD36 of human monocyte-derived macrophages in adhesion to surfaces coated with oxidized low-density lipoproteins and in secretion of H2O2.

21 January 2018

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VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase.

21 January 2018

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Activation of microglial cells by beta-amyloid protein and interferon-gamma.

21 January 2018

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Proinflammatory profile of cytokine production by human monocytes and murine microglia stimulated with beta-amyloid[25-35].

21 January 2018

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A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

21 January 2018

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Macrophage colony-stimulating factor augments beta-amyloid-induced interleukin-1, interleukin-6, and nitric oxide production by microglial cells

21 January 2018

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Indomethacin reverses the microglial response to amyloid beta-protein.

21 January 2018

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TNF-alpha mediates inducible nitric oxide synthase expression in human neuroblastoma cell line by cisplatin

21 January 2018

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Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

21 January 2018

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Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

21 January 2018

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Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease

21 January 2018

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Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease

21 January 2018

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TNF-induced signaling in apoptosis

21 January 2018

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Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.

21 January 2018

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The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

21 January 2018

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Complement activation by beta-amyloid in Alzheimer disease

21 January 2018

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Inflammation and Alzheimer's disease pathogenesis

21 January 2018

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Synergistic induction of nitric oxide by beta-amyloid and cytokines in astrocytes

21 January 2018

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

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Risk of Alzheimer's disease and duration of NSAID use.

21 January 2018

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

21 January 2018

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Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia.

21 January 2018

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Interleukin 1 and tumor necrosis factor-alpha stimulate the production of colony-stimulating factor 1 by murine astrocytes

21 January 2018

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The amino-terminus of the amyloid-beta protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages.

21 January 2018

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RETRACTED: A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide

21 January 2018

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Glia increase degeneration of hippocampal neurons through release of tumor necrosis factor-alpha.

21 January 2018

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The thrombospondin receptor CD47 (IAP) modulates and associates with alpha2 beta1 integrin in vascular smooth muscle cells

21 January 2018

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Tyrosine phosphorylation systems in Alzheimer's disease pathology

21 January 2018

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Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains

21 January 2018

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Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

21 January 2018

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RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

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Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia

21 January 2018

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Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease.

21 January 2018

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Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes

21 January 2018

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Evidence for glial-mediated inflammation in aged APP(SW) transgenic mice

21 January 2018

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A High Plasma Concentration of TNF- Is Associated With Dementia in Centenarians

21 January 2018

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Neuroglial-mediated immunoinflammatory responses in Alzheimer's disease: complement activation and therapeutic approaches

21 January 2018

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Integrins and signal transduction pathways: the road taken

21 January 2018

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Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-alpha

21 January 2018

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Subacute NO generation induced by Alzheimer's beta-amyloid in the living brain: reversal by inhibition of the inducible NO synthase

21 January 2018

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beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate

21 January 2018

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Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic Tg2576 mice with Alzheimer pathology

21 January 2018

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Expression of a synapse-associated membrane protein, P84/SHPS-1, and its ligand, IAP/CD47, in mouse retina

21 January 2018

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Matrix/integrin interaction activates the mitogen-activated protein kinase, p44erk-1 and p42erk-2

21 January 2018

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Amyloid beta protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JEMT.1121

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1 August 2017

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PubMed ID

11455613