Modeling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species-pharmacokinetic and therapeutic implications. (Q34311817)

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21 February 2020

title

Modeling hemoglobin and hemoglobin:haptoglobin complex clearance in a non-rodent species-pharmacokinetic and therapeutic implications (English)

1 reference

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21 February 2020

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4

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3

Andre F Palmer

1 reference

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21 February 2020

author name string

Felicitas S Boretti

series ordinal

1

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Jin Hyen Baek

series ordinal

2

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21 February 2020

Paul W Buehler

series ordinal

5

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21 February 2020

publication date

9 October 2014

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21 February 2020

published in

Frontiers in Physiology

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21 February 2020

volume

5

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page(s)

385

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describes a project that uses

21 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4191077/fullTextXML

inferred from PubMed Central ID database lookup

CellProfiler

object named as

Cell Profiler

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

Haptoglobin genotype-dependent differences in macrophage lysosomal oxidative injury

1 reference

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Cell-free hemoglobin and its scavenger proteins: new disease models leading the way to targeted therapies

6 July 2018

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Human Hp1-1 and Hp2-2 phenotype-specific haptoglobin therapeutics are both effective in vitro and in guinea pigs to attenuate hemoglobin toxicity.

6 July 2018

1 reference

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Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

6 July 2018

1 reference

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Structure of the haptoglobin-haemoglobin complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191077

Hemoglobin-driven pathophysiology is an in vivo consequence of the red blood cell storage lesion that can be attenuated in guinea pigs by haptoglobin therapy.

6 July 2018

1 reference

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Haptoglobin: basic and clinical aspects

6 July 2018

1 reference

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Sequestration of extracellular hemoglobin within a haptoglobin complex decreases its hypertensive and oxidative effects in dogs and guinea pigs

6 July 2018

1 reference

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Tangential flow filtration of hemoglobin

6 July 2018

1 reference

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Heme carrier protein (HCP-1) spatially interacts with the CD163 hemoglobin uptake pathway and is a target of inflammatory macrophage activation

6 July 2018

1 reference

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Gating the radical hemoglobin to macrophages: the anti-inflammatory role of CD163, a scavenger receptor.

6 July 2018

1 reference

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CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191077

Inheritance of haptoglobin subtypes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4191077

Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease

6 July 2018

1 reference

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Molecular cloning and characterization of the mouse CD163 homologue, a highly glucocorticoid-inducible member of the scavenger receptor cysteine-rich family

6 July 2018

1 reference

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Identification of the haemoglobin scavenger receptor.

6 July 2018

1 reference

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Haptoglobin in Carnivora: a unique molecular structure in bear, cat and dog haptoglobins

6 July 2018

1 reference

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Targeting dexamethasone to macrophages in a porcine endotoxemic model

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHYS.2014.00385

Effects of different glucocorticoid treatments on serum acute phase proteins in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHYS.2014.00385

Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHYS.2014.00385

Subdivision of the Three Common Haptoglobin Types based on ‘Hidden’ Differences

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHYS.2014.00385

Chromosomal Rearrangements and the Evolution of Haptoglobin Genes

21 January 2018

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https://api.crossref.org/works/10.3389%2FFPHYS.2014.00385

Haptoglobin determination in diagnosis of haemolytic diseases

21 January 2018

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12 December 2020

Pharmacological intervention for renal protection during cardiopulmonary bypass

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12 December 2020

Glucocorticoid treatment skews human monocyte differentiation into a hemoglobin-clearance phenotype with enhanced heme-iron recycling and antioxidant capacity

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12 December 2020

A monoclonal antibody to a novel differentiation antigen on human macrophages associated with the down-regulatory phase of the inflammatory process.

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12 December 2020

Induction of the CD163-dependent haemoglobin uptake by macrophages as a novel anti-inflammatory action of glucocorticoids.

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12 December 2020

Conservative treatment of hemolytic complication following coil embolization in two adult cases of patent ductus arteriosus

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12 December 2020

Extracellular hemoglobin polarizes the macrophage proteome toward Hb-clearance, enhanced antioxidant capacity and suppressed HLA class 2 expression

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12 December 2020

Efficacy of haptoglobin administration in the early postoperative course of patients with a diagnosis of HELLP syndrome

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12 December 2020

Identifiers

DOI

10.3389/FPHYS.2014.00385

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25346694%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

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21 February 2020

PubMed publication ID

25346694

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25346694%20AND%20SRC:MED&resulttype=core&format=json