2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections (Q34312282)

1 August 2017

title

2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections (English)

1 reference

1 August 2017

8

Stefan H Kappe

1 reference

1 August 2017

4

Alice Tarun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

17 July 2024

7

Mire Zloh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

17 July 2024

author name string

Deniz Tasdemir

1

1 reference

1 August 2017

David Sanabria

2

1 reference

1 August 2017

Rob Herman

5

1 reference

1 August 2017

Remo Perozzo

6

1 reference

1 August 2017

Reto Brun

9

1 reference

1 August 2017

Ina L. Lauinger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

17 July 2024

Stefan H. Kappe

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

17 July 2024

Néstor M. Carballeira

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

17 July 2024

language of work or name

English

0 references

publication date

18 September 2010

1 reference

full work available at URL

1 August 2017

https://europepmc.org/articles/pmc2981824?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20855214/pdf/?tool=EBI

17 July 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20855214/?tool=EBI

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

https://europepmc.org/articles/PMC2981824

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

https://europepmc.org/articles/PMC2981824?pdf=render

17 July 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

https://doi.org/10.1016/j.bmc.2010.08.055

17 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20855214

https://api.elsevier.com/content/article/PII:S0968089610008114?httpAccept=text/xml

17 July 2024

1 reference

Crossref

https://api.crossref.org/works/10.1016/J.BMC.2010.08.055

https://api.elsevier.com/content/article/PII:S0968089610008114?httpAccept=text/plain

17 July 2024

1 reference

Crossref

https://api.crossref.org/works/10.1016/J.BMC.2010.08.055

Bioorganic & Medicinal Chemistry

17 July 2024

published in

1 reference

1 August 2017

volume

18

1 reference

1 August 2017

issue

21

1 reference

1 August 2017

page(s)

7475-7485

1 reference

Imaging liver-stage malaria parasites

1 August 2017

cites work

1 reference

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Total synthesis and antileishmanial activity of the natural occurring acetylenic fatty acids 6-heptadecynoic acid and 6-icosynoic acid

6 July 2018

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6 July 2018

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Rodent and nonrodent malaria parasites differ in their phospholipid metabolic pathways.

6 July 2018

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6 July 2018

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The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial Parasites

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids

6 July 2018

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Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface

6 July 2018

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6 July 2018

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Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity

6 July 2018

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Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii

6 July 2018

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Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum

6 July 2018

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Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase

6 July 2018

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The novel hydroxynaphthoquinone 566C80 inhibits the development of liver stages of Plasmodium berghei cultured in vitro

6 July 2018

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Effect of methyl 2-hexadecynoate on hepatic fatty acid metabolism

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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28 October 2018

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Effect of 2-alkynoic acids on in vitro growth of bacterial and mammalian cells

28 October 2018

1 reference

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28 October 2018

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12 December 2020

Effect of 2-hexadecynoic acid on cultured 7288C hepatoma cells

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12 December 2020

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12 December 2020

Crystal structure of dimeric FabZ of Plasmodium falciparum reveals conformational switching to active hexamers by peptide flips

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

31

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Crossref

https://api.crossref.org/works/10.1016/J.BMC.2010.08.055

17 July 2024

Identifiers

1 reference

1 August 2017

1 reference

1 August 2017

1 reference