Mechanisms by which metals promote events connected to neurodegenerative diseases (Q34317899)

1 August 2017

29 March 2020

1 reference

title

Mechanisms by which metals promote events connected to neurodegenerative diseases (English)

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National Institute for Occupational Safety and Health

1 August 2017

sponsor

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29 March 2020

neurological disorder

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29 March 2020

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29 March 2020

1 reference

5

Perry G

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1 August 2017

Campbell A

1

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1 August 2017

Smith MA

series ordinal

2

1 reference

1 August 2017

Sayre LM

series ordinal

3

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1 August 2017

Bondy SC

series ordinal

4

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1 August 2017

language of work or name

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1 May 2001

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1 August 2017

published in

Brain Research Bulletin

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1 August 2017

29 March 2020

55

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1 August 2017

issue

2

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1 August 2017

page(s)

125-132

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UCLA School of Public Health

1 August 2017

performing organization

object named as

University of California, School of Public Health, Los Angeles, CA

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NIOSHTIC-2

on focus list of Wikimedia project

2 February 2024

Wikimedia–NIOSH collaboration

0 references

1 reference

25 September 2023

Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

The dialysis encephalopathy syndrome. Possible aluminum intoxication

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Function and activation of NF-kappa B in the immune system

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

1 reference

7 January 2021

Evidence for an early inflammatory response in the central nervous system of mice with scrapie.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

The promotion of iron-induced generation of reactive oxygen species in nerve tissue by aluminum

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Aluminum but not iron treatment induces pro-oxidant events in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Elevated "hydroxyl radical" generation in vivo in an animal model of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Prion protein expression and superoxide dismutase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Microglial expression of the prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Effects of copper on survival of prion protein knockout neurons and glia.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Normal prion protein has an activity like that of superoxide dismutase.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Prion protein peptide neurotoxicity can be mediated by astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Regulation of the release of interleukin-6 from human astrocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Aluminum-induced oxidative events in cell lines: glioma are more responsive than neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Prion protein glycosylation is sensitive to redox change

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Interleukin-1beta activates forebrain glial cells and increases nitric oxide production and cortical glutamate and GABA release in vivo: implications for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin?

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Abnormal iron deposition associated with lipid peroxidation in transgenic mice expressing interleukin-6 in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Effects of postnatal aluminum exposure on biological parameters in the rat plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Mitochondrial dysfunction induced by oxidative stress in the brains of hamsters infected with the 263 K scrapie agent

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Aluminium toxicity and metal speciation: established data and open questions

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Inflammatory nodular reactions after hepatitis B vaccination due to aluminium sensitization

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Brain Aluminum Distribution in Alzheimer's Disease and Experimental Neurofibrillary Degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Complement activation by cross-linked truncated and chimeric full-length beta-amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Perivascular astrocytes within Alzheimer's disease plaques

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Glial reaction in the hippocampal formation is highly correlated with aging in human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Oxidative stress and overexpression of manganese superoxide dismutase in patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Aluminum in total parenteral nutrition solutions produces portal inflammation in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Tumor necrosis factor-alpha increases lactoferrin transcytosis through the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Induction of production of nitric oxide in microglial cells by insoluble form of aluminium

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Mutant superoxide dismutase-1-linked familial amyotrophic lateral sclerosis: molecular mechanisms of neuronal death and protection

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Amyloid beta peptide potentiates cytokine secretion by interleukin-1 beta-activated human astrocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Reactions of hydrogen peroxide with familial amyotrophic lateral sclerosis mutant human copper-zinc superoxide dismutases studied by pulse radiolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Glial-derived proteins activate cultured astrocytes and enhance beta amyloid-induced glial activation

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Effect of aluminum on regional brain antioxidant defense status in Wistar rats

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Essential trace element alterations in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapie-infected mice

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Effects of interferon-gamma and lipopolysaccharide on macrophage iron metabolism are mediated by nitric oxide-induced degradation of iron regulatory protein 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

The familial amyotrophic lateral sclerosis-associated amino acid substitutions E100G, G93A, and G93R do not influence the rate of inactivation of copper- and zinc-containing superoxide dismutase by H2O2

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Copper, iron and zinc in Alzheimer's disease senile plaques

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Increased peroxidation and reduced antioxidant enzyme activity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Risk for neuropathologically confirmed Alzheimer's disease and residual aluminum in municipal drinking water employing weighted residential histories

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Copper/zinc ratio and systemic oxidant load: effect of aging and aging-related degenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Early glycoxidation damage in brains from Down's syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Iron-Mediated Generation of the Neurotoxin 6-Hydroxydopamine Quinone by Reaction of Fatty Acid Hydroperoxides with Dopamine: A Possible Contributory Mechanism for Neuronal Degeneration in Parkinson's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Encephalopathy after bladder irrigation with alum: case report and literature review

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Prion protein fragment 106-126 differentially induces heme oxygenase-1 mRNA in cultured neurons and astroglial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Complement activation by beta-amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Aluminium intoxication in undialysed adults with chronic renal failure

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Beta(1-40) amyloid peptide injection into the nucleus basalis of rats induces microglia reaction and enhances cortical gamma-aminobutyric acid release in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Astrocytes, brain aging, and neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Astrocyte mitochondria: a substrate for iron deposition in the aging rat substantia nigra

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Amyloid peptides are toxic via a common oxidative mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Activation of microglial cells by PrP and beta-amyloid fragments raises intracellular calcium through L-type voltage sensitive calcium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Reexamination of the mechanism of hydroxyl radical adducts formed from the reaction between familial amyotrophic lateral sclerosis-associated Cu,Zn superoxide dismutase mutants and H2O2.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Advanced Maillard reaction end products are associated with Alzheimer disease pathology

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Oxidative damage in Alzheimer's.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Iron accumulation in Alzheimer disease is a source of redox-generated free radicals

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Abnormal localization of iron regulatory protein in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Reactive microgliosis

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Cytokines associated with amyloid plaques in Alzheimer's disease brain stimulate human glial and neuronal cell cultures to secrete early complement proteins, but not C1-inhibitor.

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents postischemic injury

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

The stabilization of ferrous iron by a toxic beta-amyloid fragment and by an aluminum salt

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

An aluminum-induced increase in GFAP is attenuated by some chelators

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Activated microglia cause iron-dependent lipid peroxidation in the presence of ferritin

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

Free radical formation in autopsy samples of Alzheimer and control cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0361-9230%2801%2900455-5

7 January 2021

10.1016/S0361-9230(01)00455-5

Identifiers

DOI

1 reference

1 August 2017

1 reference

29 March 2020

1 reference