Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis (Q34321879)

1 August 2017

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title

Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis (English)

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polycystic ovary syndrome

1 August 2017

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Mora Murri

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1 August 2017

Manuel Luque-Ramírez

2

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1 August 2017

María Insenser

3

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1 August 2017

Miriam Ojeda-Ojeda

4

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1 August 2017

Hector F Escobar-Morreale

5

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1 August 2017

language of work or name

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9 January 2013

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Human Reproduction Update

1 August 2017

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1 August 2017

19

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1 August 2017

3

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1 August 2017

268-288

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Vitamin C supplementation decreases insulin glycation and improves glucose homeostasis in obese hyperglycemic (ob/ob) mice.

1 August 2017

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The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

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Homocysteine and ghrelin link with polcystic ovary syndrome in relation to obesity.

21 January 2018

1 reference

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The evaluation of endothelial function with flow-mediated dilatation and carotid intima media thickness in young nonobese polycystic ovary syndrome patients; existence of insulin resistance alone may not represent an adequate condition for deteriora

21 January 2018

1 reference

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Serum resistin and adiponectin levels in young non-obese women with polycystic ovary syndrome

21 January 2018

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Serum levels of leptin and homocysteine in women with polycystic ovary syndrome and its relationship to endocrine, clinical and metabolic parameters

21 January 2018

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The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report

21 January 2018

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Plasma homocysteine and polycystic ovary syndrome: the missed link

21 January 2018

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Assessment of paraoxonase 1, xanthine oxidase and glutathione peroxidase activities, nitric oxide and thiol levels in women with polycystic ovary syndrome.

21 January 2018

1 reference

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Vascular risk in young women with polycystic ovary and polycystic ovary syndrome

21 January 2018

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L-arginine plus drospirenone-ethinyl estradiol in the treatment of patients with PCOS: a prospective, placebo controlled, randomised, pilot study

21 January 2018

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Elevated levels of oxidized low-density lipoprotein and of catalase activity in follicular fluid of obese women

21 January 2018

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Development and validation of MIX: comprehensive free software for meta-analysis of causal research data

21 January 2018

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Paraoxonase lactonase activity (PON-HTLase), asymmetric dimethylarginine (ADMA) and platelet activating factor-acetylhydrolase (PAF-AH) activity in non-obese women with PCOS.

21 January 2018

1 reference

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Plasma homocysteine levels in polycystic ovary syndrome and congenital adrenal hyperplasia

21 January 2018

1 reference

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Evaluation of endothelial dysfunction, lipid metabolism in women with polycystic ovary syndrome: relationship of paraoxonase 1 activity, malondialdehyde levels, low-density lipoprotein subfractions, and endothelial dysfunction

21 January 2018

1 reference

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Homocysteine concentrations in follicular fluid are associated with poor oocyte and embryo qualities in polycystic ovary syndrome patients undergoing assisted reproduction.

21 January 2018

1 reference

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Cardiovascular risk in women with polycystic ovarian syndrome (PCOS)

21 January 2018

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Factors associated with oxidative stress in human populations

21 January 2018

1 reference

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Increased C-reactive protein levels in the polycystic ovary syndrome: a marker of cardiovascular disease

21 January 2018

1 reference

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Effects of two different oral contraceptives on homocysteine metabolism in women with polycystic ovary syndrome.

21 January 2018

1 reference

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Phenotypic variation in hyperandrogenic women influences the findings of abnormal metabolic and cardiovascular risk parameters

21 January 2018

1 reference

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Apolipoprotein E gene polymorphism and polycystic ovary syndrome patients in Western Anatolia, Turkey

21 January 2018

1 reference

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The administration of estrogens, combined with anti-androgens, has beneficial effects on the hormonal features and asymmetric dimethyl-arginine levels, in women with the polycystic ovary syndrome.

21 January 2018

1 reference

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Effect of follicular fluid oxidative stress on meiotic spindle formation in infertile women with polycystic ovarian syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Serum leptin, oxidized low density lipoprotein and plasma asymmetric dimethylarginine levels and their relationship with dyslipidaemia in adolescent girls with polycystic ovary syndrome.

21 January 2018

1 reference

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Meta-analysis in clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Effect of sex hormones on lipid peroxidation in women with polycystic ovary syndrome, healthy women, and men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

DNA damage, DNA susceptibility to oxidation and glutathione level in women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Inositol administration reduces oxidative stress in erythrocytes of patients with polycystic ovary syndrome.

21 January 2018

1 reference

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How to select, calculate, and interpret effect sizes

21 January 2018

1 reference

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Decreased serum paraoxonase 1 (PON1) activity: an additional risk factor for atherosclerotic heart disease in patients with PCOS?

21 January 2018

1 reference

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Bias in meta-analysis detected by a simple, graphical test

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Polycystic Ovary Syndrome

21 January 2018

1 reference

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Thrombin-activatable fibrinolysis inhibitor and cardiovascular risk factors in polycystic ovary syndrome

21 January 2018

1 reference

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The relationship of the interleukin-6 -174 G>C gene polymorphism with oxidative stress markers in Turkish polycystic ovary syndrome patients

21 January 2018

1 reference

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The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Abdominal adiposity and the polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes

21 January 2018

1 reference

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Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

21 January 2018

1 reference

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Apolipoprotein E-containing HDL-associated platelet-activating factor acetylhydrolase activities and malondialdehyde concentrations in patients with PCOS.

21 January 2018

1 reference

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Decreased total antioxidant status and increased oxidative stress in women with polycystic ovary syndrome may contribute to the risk of cardiovascular disease

21 January 2018

1 reference

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Insulin resistance, inflammation, and serum fatty acid composition.

21 January 2018

1 reference

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21 January 2018

1 reference

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The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways

21 January 2018

1 reference

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Soluble CD36 and risk markers of insulin resistance and atherosclerosis are elevated in polycystic ovary syndrome and significantly reduced during pioglitazone treatment.

21 January 2018

1 reference

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Polycystic ovary syndrome, the G1691A factor V Leiden mutation, and plasminogen activator inhibitor activity: associations with recurrent pregnancy loss

21 January 2018

1 reference

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Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome

21 January 2018

1 reference

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Polycystic ovary syndrome: etiology, pathogenesis and diagnosis

21 January 2018

1 reference

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Micronucleus frequency in lymphocytes and 8-hydroxydeoxyguanosine level in plasma of women with polycystic ovary syndrome.

21 January 2018

1 reference

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Oral contraceptive plus antiandrogen therapy and cardiometabolic risk in polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Metabolic and endocrine effects of metformin and metformin plus cyclic medroxyprogesterone acetate in women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Asymmetrical dimethylarginine, inflammatory and metabolic parameters in women with polycystic ovary syndrome before and after metformin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Adiponectin and adiponectin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Oxidative stress markers in young patients with polycystic ovary syndrome, the relationship between insulin resistances

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Methylenetetrahydrofolate reductase C677T gene polymorphism in Turkish patients with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Effect Of G2706A and G1051A polymorphisms of the ABCA1 gene on the lipid, oxidative stress and homocystein levels in Turkish patients with polycystıc ovary syndrome

21 January 2018

1 reference

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Cardiovascular risk factors in polycystic ovary syndrome

21 January 2018

1 reference

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Comparative effects of atorvastatin and simvastatin on the plasma total homocysteine levels in women with polycystic ovary syndrome: a prospective randomized study

21 January 2018

1 reference

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Advanced oxidation protein products are increased in women with polycystic ovary syndrome: relationship with traditional and nontraditional cardiovascular risk factors in patients with polycystic ovary syndrome

21 January 2018

1 reference

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Obesity and insulin resistance associated with lower plasma vitamin B12 in PCOS.

21 January 2018

1 reference

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Relationship between interleukin-6 levels and ambulatory blood pressure in women with polycystic ovary syndrome.

21 January 2018

1 reference

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Plasma interleukin-18 levels are increased in the polycystic ovary syndrome: relationship of carotid intima-media wall thickness and cardiovascular risk factors

21 January 2018

1 reference

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C-reactive protein and homocysteine levels are associated with abnormal heart rate recovery in women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Comparison of the effects of atorvastatin and simvastatin in women with polycystic ovary syndrome: A prospective, randomized study

21 January 2018

1 reference

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Effect of folic acid in women with and without insulin resistance who have hyperhomocysteinemic polycystic ovary syndrome.

21 January 2018

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N-acetyl-cysteine treatment for polycystic ovary syndrome

21 January 2018

1 reference

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Relationship between homocysteine and insulin resistance in women with polycystic ovary syndrome

21 January 2018

1 reference

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Homocysteine levels in women with polycystic ovary syndrome treated with metformin versus rosiglitazone: a randomized study.

21 January 2018

1 reference

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Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin: a randomized trial

21 January 2018

1 reference

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Body composition characteristics are associated with the bone density of the proximal femur end in middle- and old-aged women and men.

21 January 2018

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Effect of surgical weight loss on free radical and antioxidant balance: a preliminary report

21 January 2018

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Plasma homocysteine levels in obese and non-obese subjects with or without hypertension; its relationship with oxidative stress and copper

21 January 2018

1 reference

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Oxidative stress but not endothelial dysfunction exists in non-obese, young group of patients with polycystic ovary syndrome

21 January 2018

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Symmetric dimethylarginine (SDMA) is raised in women with polycystic ovary syndrome: a pilot study.

21 January 2018

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Androgen excess produces systemic oxidative stress and predisposes to beta-cell failure in female mice

21 January 2018

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The plasma homocysteine levels are increased in polycystic ovary syndrome

21 January 2018

1 reference

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Effects of an antiandrogenic oral contraceptive pill compared with metformin on blood coagulation tests and endothelial function in women with the polycystic ovary syndrome: influence of obesity and smoking

21 January 2018

1 reference

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Oxidised low-density lipoprotein concentration - early marker of an altered lipid metabolism in young women with PCOS.

21 January 2018

1 reference

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Serum high-sensitivity C-reactive protein and homocysteine changes during hormonal therapy in women with polycystic ovary syndrome: a prospective, matched study.

21 January 2018

1 reference

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Endothelial function and its relationship to leptin, homocysteine, and insulin resistance in lean and overweight eumenorrheic women and PCOS patients: a pilot study

21 January 2018

1 reference

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Drospirenone and cardiovascular risk in lean and obese polycystic ovary syndrome patients: a pilot study

21 January 2018

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The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria

21 January 2018

1 reference

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Hepatic steatosis in young lean insulin resistant women with polycystic ovary syndrome

21 January 2018

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Effects of controlled-release alpha lipoic acid in lean, nondiabetic patients with polycystic ovary syndrome

21 January 2018

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Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle

21 January 2018

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Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells

21 January 2018

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Polycystic ovaries and associated clinical and biochemical features in young women

21 January 2018

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Serum paraoxonase 1 activity and oxidant/antioxidant status in Saudi women with polycystic ovary syndrome

21 January 2018

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Cardiovascular disease markers in women with polycystic ovary syndrome with emphasis on asymmetric dimethylarginine and homocysteine

21 January 2018

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A possible role for familial thrombophilia in women with polycystic ovarian syndrome.

21 January 2018

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A comprehensive assessment of endothelial function in overweight women with and without polycystic ovary syndrome

21 January 2018

1 reference

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Vascular function in the diagnostic categories of polycystic ovary syndrome.

21 January 2018

1 reference

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The cardiovascular risk factor homocysteine is not elevated in young women with hyperandrogenism or hypoestrogenism

21 January 2018

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Changes in oxidative stress and insulin resistance in morbidly obese patients after bariatric surgery.

21 January 2018

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The effect of serum and intrafollicular insulin resistance parameters and homocysteine levels of nonobese, nonhyperandrogenemic polycystic ovary syndrome patients on in vitro fertilization outcome

21 January 2018

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Determinants of insulin responsiveness in young women: Impact of polycystic ovarian syndrome, nitric oxide, and vitamin D.

21 January 2018

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JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes

21 January 2018

1 reference

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Polycystic ovary syndrome is associated with elevated plasma soluble CD40 ligand, a marker of coronary artery disease

21 January 2018

1 reference

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Homocysteine levels and C677T polymorphism of methylenetetrahydrofolate reductase in women with polycystic ovary syndrome

21 January 2018

1 reference

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Increased oxidative stress and hypozincemia in male obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Metformin and oral contraceptive treatments reduced circulating asymmetric dimethylarginine (ADMA) levels in patients with polycystic ovary syndrome (PCOS).

21 January 2018

1 reference

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The presence of antibodies to oxidative modified proteins in serum from polycystic ovary syndrome patients.

21 January 2018

1 reference

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Polycystic ovary syndrome and the single nucleotide polymorphisms of methylenetetrahydrofolate reductase: a pilot observational study

21 January 2018

1 reference

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Plasma homocysteine concentrations and the single nucleotide polymorphisms in the methionine synthase gene (MTR 2756A>G): Associations with the polycystic ovary syndrome An observational study

21 January 2018

1 reference

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Effects of metformin with or without supplementation with folate on homocysteine levels and vascular endothelium of women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Asymmetric dimethylarginine levels and carotid intima-media thickness in obese patients with polycystic ovary syndrome and their relationship to metabolic parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Effect of lifestyle modification and metformin therapy on emerging cardiovascular risk factors in overweight Indian women with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Polycystic ovary syndrome is associated with severe platelet and endothelial dysfunction in both obese and lean subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Exercise decreases plasma total homocysteine in overweight young women with polycystic ovary syndrome

21 January 2018

1 reference

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Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes

21 January 2018

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Antioxidants induce apoptosis of rat ovarian theca-interstitial cells

21 January 2018

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Oxidative stress in polycystic ovary syndrome and its contribution to the risk of cardiovascular disease

21 January 2018

1 reference

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Prevalence of functional disorders of androgen excess in unselected premenopausal women: a study in blood donors.

21 January 2018

1 reference

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Insulin resistance in patients with polycystic ovary syndrome is associated with elevated plasma homocysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Increased arterial stiffness in nonobese women with polycystic ovary syndrome (PCOS) without comorbidities: one more characteristic inherent to the syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Distinctively low levels of serum 8-hydroxydeoxyguanosine in women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Serum paraoxonase 1 activity, asymmetric dimethylarginine levels, and brachial artery flow-mediated dilatation in women with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

ADMA and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Control of oxidative stress and metabolic homeostasis by the suppression of postprandial hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Endothelial function and insulin resistance in polycystic ovary syndrome: the effects of medical therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Do young women with polycystic ovary syndrome show early evidence of preclinical coronary artery disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance

21 January 2018

1 reference

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Evaluation of asymmetric dimethylarginine, nitric oxide levels and associated independent variables in obese and lean patients with polycystic ovarian syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Mitochondrial formation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Mechanisms of homocysteine-induced oxidative stress

21 January 2018

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Oxidative stress is associated with adiposity and insulin resistance in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Changes in leptin, plasminogen activator factor and oxidative stress in morbidly obese patients following open and laparoscopic Swedish adjustable gastric banding

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Free radicals, metals and antioxidants in oxidative stress-induced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Free radicals and antioxidants in normal physiological functions and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

The in vitro oxidizability of lipoprotein particles in obese and non-obese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Oxidative stress in nonobese women with polycystic ovary syndrome: correlations with endocrine and screening parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Mitochondrial complex I impairment in leukocytes from polycystic ovary syndrome patients with insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Biomarkers and potential mechanisms of obesity-induced oxidant stress in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Oxidative stress and potential interventions to reduce oxidative stress in overweight and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Plasma thiols and androgen levels in polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Plasma homocysteine in polycystic ovary syndrome: does it correlate with insulin resistance and ethnicity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Antioxidant supplemention in the treatment of skeletal muscle insulin resistance: potential mechanisms and clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Diastolic dysfunction and increased serum homocysteine concentrations may contribute to increased cardiovascular risk in patients with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Serum retinol-binding protein 4, leptin, and plasma asymmetric dimethylarginine levels in obese and nonobese young women with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Glucose intolerance, insulin resistance and cardiovascular risk factors in first degree relatives of women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

Levels of lipoprotein and homocysteine in non-obese and obese patients with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

The effects of rosiglitazone and metformin on oxidative stress and homocysteine levels in lean patients with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

The correlation of plasma homocysteine with insulin resistance in polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

What makes a good genetic association study?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHUMUPD%2FDMS059

21 January 2018

Identifiers

DOI

10.1093/HUMUPD/DMS059

1 reference

release_c4d4nnr3kjajvj4fxs7ofwpvde

1 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/c4d4nnr3kjajvj4fxs7ofwpvde

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference