Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site (Q34323300)

1 August 2017

title

Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site (English)

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1 August 2017

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Uttam Pal

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author name string

Deep Sankar Rudra

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Nakul Chandra Maiti

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Russel J Reiter

4

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Snehasikta Swarnakar

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publication date

17 January 2013

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Journal of Pineal Research

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published in

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volume

54

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issue

4

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page(s)

398-405

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Matrix metalloproteinases

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cites work

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Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed

21 January 2018

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On the size of the active site in proteases. I. Papain. 1967.

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Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism

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Gelatinase B: a tuner and amplifier of immune functions.

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Cell surface association of matrix metalloproteinase-9 (gelatinase B).

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Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion

21 January 2018

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MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

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Matrix metalloproteinase-9 is required for adequate angiogenic revascularization of ischemic tissues: potential role in capillary branching.

21 January 2018

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Matrix metalloproteinase-9 and autoimmune diseases

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In bacterial meningitis cortical brain damage is associated with changes in parenchymal MMP-9/TIMP-1 ratio and increased collagen type IV degradation

21 January 2018

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A novel rationale for inhibition of gelatinase B in multiple sclerosis: MMP-9 destroys alpha B-crystallin and generates a promiscuous T cell epitope.

21 January 2018

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Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9)

21 January 2018

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New functions for the matrix metalloproteinases in cancer progression

21 January 2018

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Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

21 January 2018

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Matrix metalloproteinase-9 from bone marrow-derived cells contributes to survival but not growth of tumor cells in the lung microenvironment

21 January 2018

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Matrix metalloproteinase inhibitors

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Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat

21 January 2018

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Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity

21 January 2018

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Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants

21 January 2018

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Downregulation of matrix metalloproteinase-9 by melatonin during prevention of alcohol-induced liver injury in mice.

21 January 2018

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Molecular pathways involved in seasonal body weight and reproductive responses governed by melatonin.

21 January 2018

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Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.

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New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin

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A Review of the Multiple Actions of Melatonin on the Immune System

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Melatonin as a natural ally against oxidative stress: a physicochemical examination.

21 January 2018

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Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger.

21 January 2018

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An alternative therapy for idiopathic pulmonary fibrosis by doxycycline through matrix metalloproteinase inhibition

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Activity-based probes for the proteomic profiling of metalloproteases

21 January 2018

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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

21 January 2018

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Matrix metalloproteinases in health and disease: regulation by melatonin

21 January 2018

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Melatonin ameliorates experimental hepatic fibrosis induced by carbon tetrachloride in rats

21 January 2018

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Melatonin protects against alcoholic liver injury by attenuating oxidative stress, inflammatory response, and apoptosis.

21 January 2018

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Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis

21 January 2018

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Immunogenic Consensus Sequence T helper Epitopes for a Pan-Burkholderia Biodefense Vaccine.

21 January 2018

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Angiogenesis extent and expression of matrix metalloproteinase-2 and -9 correlate with upgrading and myometrial invasion in endometrial carcinoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JPI.12034

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1 August 2017

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