The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy (Q34325749)

1 August 2017

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title

The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy (English)

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1 August 2017

M W Pedersen

1

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1 August 2017

M Meltorn

series ordinal

2

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1 August 2017

L Damstrup

series ordinal

3

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1 August 2017

H S Poulsen

series ordinal

4

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1 August 2017

1 June 2001

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1 August 2017

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1 August 2017

12

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1 August 2017

745-760

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1 August 2017

6

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EGF receptor amplification and expression in human brain tumours

1 August 2017

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Epidermal growth factor receptor (EGFr) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Overexpression of EGFR and c-erbB2 causes enhanced cell migration in human breast cancer cells and NIH3T3 fibroblasts

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

The autocrine loop of TGF-alpha/EGFR and brain tumors

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

EGFR gene amplification--rearrangement in human glioblastomas

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Constitutive activation of c-Jun N-terminal kinase by a mutant epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Structural alterations of the epidermal growth factor receptor gene in human gliomas

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

The epidermal growth factor

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Disulfide bond structure of human epidermal growth factor receptor.

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptor

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Epidermal growth factor receptors: critical mediators of multiple receptor pathways

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https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII).

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

CD16-mediated activation of phosphatidylinositol-3 kinase (PI-3K) in human NK cells involves tyrosine phosphorylation of Cbl and its association with Grb2, Shc, pp36 and p85 PI-3K subunit

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Bcl-2 family: life-or-death switch

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Function of aberrant EGFR in malignant gliomas.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Expression of activated epidermal growth factor receptors, Ras-guanosine triphosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Role of an anti-epidermal growth factor receptor in treating cancer

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Epidermal growth factor-related peptides and their receptors in human malignancies

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Specific inhibition of epidermal growth factor receptor tyrosine kinase by 4-anilinoquinazolines

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Combinatorial chemoprevention of intestinal neoplasia

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Radiosensitization of human breast cancer cells by a novel ErbB family receptor tyrosine kinase inhibitor.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Therapeutic potential of chimeric and murine anti-(epidermal growth factor receptor) antibodies in a metastasis model for human melanoma.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

In vitro and in vivo stability and anti-tumour efficacy of an anti-EGFR/anti-CD3 F(ab')2 bispecific monoclonal antibody

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Clinical experience with CD64-directed immunotherapy. An overview

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Monoclonal antibody therapy of human gliomas: current status and future approaches

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Gene inhibition using antisense oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Targeting retrovirus to cancer cells expressing a mutant EGF receptor by insertion of a single chain antibody variable domain in the envelope glycoprotein receptor binding lobe

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Monoclonal antibody against the fusion junction of a deletion-mutant epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Suppression of metastasis formation by a recombinant single chain antibody-toxin targeted to full-length and oncogenic variant EGF receptors

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Marked inhibition of glioblastoma target cell tumorigenicity in vitro by retrovirus-mediated transfer of a hairpin ribozyme against deletion-mutant epidermal growth factor receptor messenger RNA.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Inhibition of tumor growth by ribozyme-mediated suppression of aberrant epidermal growth factor receptor gene expression.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

A genetically modified allogeneic cellular vaccine generates MHC class I-restricted cytotoxic responses against tumor-associated antigens and protects against CNS tumors in vivo.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Glycosylation-induced conformational modification positively regulates receptor-receptor association: a study with an aberrant epidermal growth factor receptor (EGFRvIII/DeltaEGFR) expressed in cancer cells

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1011177318162

7 January 2021

Identifiers

DOI

10.1023/A:1011177318162

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1 August 2017

1 reference