Oxidative damage and mitochondrial decay in aging (Q34326443)

1 August 2017

1 reference

title

Oxidative damage and mitochondrial decay in aging (English)

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1 August 2017

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3

B N Ames

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1 August 2017

M K Shigenaga

1

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PubMed ID

7971961

1 August 2017

T M Hagen

series ordinal

2

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PubMed ID

7971961

1 August 2017

language of work or name

English

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publication date

1 November 1994

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

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1 August 2017

91

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1 August 2017

10771-10778

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1 August 2017

23

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Tissue cytochrome oxidase activity and body weight.

1 August 2017

1 reference

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Age-dependent impairment of mitochondrial function in primate brain.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Oxidants, antioxidants, and the degenerative diseases of aging

6 July 2018

1 reference

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Rat liver mitochondrial phospholipase A2 is an endotoxin-stimulated membrane-associated enzyme of Kupffer cells which is released during liver perfusion

6 July 2018

1 reference

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Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

6 July 2018

1 reference

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Decline with age of the respiratory chain activity in human skeletal muscle.

6 July 2018

1 reference

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Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

6 July 2018

1 reference

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Oxidative stress, glutamate, and neurodegenerative disorders

6 July 2018

1 reference

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Do defects in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?

6 July 2018

1 reference

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Structural and replicative forms of mitochondrial DNA in tissues from adult and senescent BALB/c mice and Fischer 344 rats.

6 July 2018

1 reference

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1 reference

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Bioenergetics in aging

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6 July 2018

1 reference

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Normal oxidative damage to mitochondrial and nuclear DNA is extensive

6 July 2018

1 reference

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6 July 2018

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6 July 2018

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6 July 2018

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Sequence analysis of cDNAs for the human and bovine ATP synthase beta subunit: mitochondrial DNA genes sustain seventeen times more mutations

6 July 2018

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6 July 2018

1 reference

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6 July 2018

1 reference

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Effect of chronic caloric restriction on physiological variables related to energy metabolism in the male Fischer 344 rat.

6 July 2018

1 reference

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6 July 2018

DNA, mutations and aging

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6 July 2018

1 reference

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6 July 2018

1 reference

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6 July 2018

1 reference

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Superoxide anion radical production in different animal species

6 July 2018

1 reference

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Cytochrome c oxidase deficiency in Leigh's syndrome: genetic evidence for a nuclear DNA-encoded mutation.

6 July 2018

1 reference

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Membrane signal transduction in T cells in aging humans

6 July 2018

1 reference

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Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced

6 July 2018

1 reference

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Immunological parameters in aging: studies on natural immunomodulatory and immunoprotective substances

6 July 2018

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6 July 2018

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Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

6 July 2018

1 reference

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Reversible inhibition of electron transfer in the ubiquinol. Cytochrome c reductase segment of the mitochondrial respiratory chain in hibernating ground squirrels.

6 July 2018

1 reference

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Detection of a specific mitochondrial DNA deletion in tissues of older humans

6 July 2018

1 reference

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6 July 2018

1 reference

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Excitatory amino acid neurotoxicity and neurodegenerative disease

6 July 2018

1 reference

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Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

6 July 2018

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1 reference

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6 July 2018

1 reference

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6 July 2018

1 reference

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6 July 2018

1 reference

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6 July 2018

1 reference

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6 July 2018

1 reference

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Hydrogen peroxide release by mitochondria increases during aging

6 July 2018

1 reference

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Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondrial DNA of human diaphragm

6 July 2018

1 reference

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Evolution of energy metabolism. Proton permeability of the inner membrane of liver mitochondria is greater in a mammal than in a reptile

6 July 2018

1 reference

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Effect of acetyl-L-carnitine on the dopaminergic system in aging brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Changes in the rat liver mitochondrial DNA upon aging

6 July 2018

1 reference

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Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Redox modulatory site of the NMDA receptor-channel complex: regulation by oxidized glutathione

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1 reference

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6 July 2018

1 reference

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Reactive oxygen species: relation to aging and neurotoxic damage

6 July 2018

1 reference

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1 reference

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6 July 2018

1 reference

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Reactive oxygen species and the central nervous system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Cell culture models for oxidative stress: superoxide and hydrogen peroxide versus normobaric hyperoxia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Mitochondrial production of pro-oxidants and cellular senescence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Mitochondrial DNA mutation and the ageing process: bioenergy and pharmacological intervention

6 July 2018

1 reference

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Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Deleterious mitochondrial DNA mutations accumulate in aging human tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

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6 July 2018

1 reference

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6 July 2018

1 reference

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Protein oxidation and aging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Stimulation of nerve growth factor receptors in PC12 by acetyl-L-carnitine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Changes in major phospholipids of mitochondria during postischemic reperfusion in rat brain.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Biochemical and stereological analysis of rat liver mitochondria in different thyroid states

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Phospholipase A2 of rat liver mitochondria in vitamin E deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Lipid oxidation by heart mitochondria from young adult and senescent rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Longevity, aging and comparative cellular and molecular biology of the house mouse, Mus musculus, and the white-footed mouse, Peromyscus leucopus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Do Mitochondria Produce Oxygen Radicals in vivo?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

The Effect of Age on Mitochondrial Ultrastructure and Enzymes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Mitochondrial impairment reduces the threshold for in vivo NMDA-mediated neuronal death in the striatum.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Conformational changes in oxidized phospholipids and their preferential hydrolysis by phospholipase A2: a monolayer study.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Human aging is associated with various point mutations in tRNA genes of mitochondrial DNA.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Mitochondrial oxidative damage, hydrogen peroxide release, and aging.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Variation in the frequency of complex forms of mitochondrial DNA in different brain regions of senescent mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Cholinergic systems in aging: the role of oxidative stress.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Culture of dorsal root ganglion neurons from aged rats: effects of acetyl-L-carnitine and NGF

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Characterization of carnitine acylcarnitine translocase system of heart mitochondria.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

Food, reproduction and L'ongevity: Is the extended lifespan of calorie-restricted animals an evolutionary adaptation?

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45108

27 October 2018

1 reference

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1 reference

12 December 2020

Decreased activity of the phosphate carrier and modification of lipids in cardiac mitochondria from senescent rats

1 reference

12 December 2020

Age changes of mitochondria of rat kidney

1 reference

12 December 2020

1 reference

12 December 2020

Progressive loss of cytochrome c oxidase in the human extraocular muscles in ageing--a cytochemical-immunohistochemical study

1 reference

12 December 2020

A new method for testing cell ageing using two mitochondria specific fluorescent probes

1 reference

12 December 2020

Correlation of lymphocyte lipid composition membrane microviscosity and mitogen response in the aged

1 reference

12 December 2020

Changes in mitochondrial lipids of rat kidney during ischemia

1 reference

12 December 2020

The effects of ubidecarenone derivatives on the action of phospholipase

1 reference

12 December 2020

The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages

1 reference

12 December 2020

Oxidative phosphorylation in mitochondria from aged rats

1 reference

12 December 2020

The proton leak across the mitochondrial inner membrane

1 reference

12 December 2020

Liver mitochondrial respiratory functions decline with age

1 reference

12 December 2020

DECLINE IN SKELETAL MUSCLE MITOCHONDRIAL RESPIRATORY CHAIN FUNCTION: POSSIBLE FACTOR IN AGEING

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.91.23.10771

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference

PubMed ID

7971961