Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice (Q34330253)

1 August 2017

title

Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice (English)

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1 August 2017

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7

Robert V Farese

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1 August 2017

Emily L Willner

1

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1 August 2017

Bryan Tow

2

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1 August 2017

Kimberly K Buhman

3

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1 August 2017

Martha Wilson

4

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1 August 2017

David A Sanan

5

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1 August 2017

Lawrence L Rudel

6

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1 August 2017

language of work or name

English

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publication date

21 January 2003

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

100

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1 August 2017

issue

3

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1 August 2017

page(s)

1262-1267

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 August 2017

cites work

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6 July 2018

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Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals

6 July 2018

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Transgenic mice that overexpress mouse apolipoprotein B. Evidence that the DNA sequences controlling intestinal expression of the apolipoprotein B gene are distant from the structural gene

6 July 2018

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Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells

6 July 2018

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Tissue-specific expression and cholesterol regulation of acylcoenzyme A:cholesterol acyltransferase (ACAT) in mice. Molecular cloning of mouse ACAT cDNA, chromosomal localization, and regulation of ACAT in vivo and in vitro

6 July 2018

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6 July 2018

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The functional characteristics of a human apolipoprotein E variant (cysteine at residue 142) may explain its association with dominant expression of type III hyperlipoproteinemia

6 July 2018

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Two different views of the relationship of hypertriglyceridemia to coronary heart disease. Implications for treatment

6 July 2018

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Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

6 July 2018

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Hepatic ACAT activity in African green monkeys is highly correlated to plasma LDL cholesteryl ester enrichment and coronary artery atherosclerosis

6 July 2018

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Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

6 July 2018

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Primates highly responsive to dietary cholesterol up-regulate hepatic ACAT2, and less responsive primates do not.

6 July 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0336398100

Transgenic overexpression of human lecithin: cholesterol acyltransferase (LCAT) in mice does not increase aortic cholesterol deposition

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0336398100

Acyl-CoA:cholesterol acyltransferase inhibition reduces atherosclerosis in apolipoprotein E-deficient mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0336398100

In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice.

21 January 2018

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Tissue expression studies on the mouse acyl-CoA: cholesterol acyltransferase gene (Acact): findings supporting the existence of multiple cholesterol esterification enzymes in mice.

27 October 2018

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Lecithin-cholesterol acyltransferase. Assay of cholesterol esterification and phospholipase A2 activities

27 October 2018

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12 December 2020

The ACAT inhibitor avasimibe reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits

1 reference

12 December 2020

Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia

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12 December 2020

Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis

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12 December 2020

High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase

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12 December 2020

Mice overexpressing human lecithin: cholesterol acyltransferase are not protected against diet-induced atherosclerosis

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0336398100

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1 August 2017

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1 August 2017

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