Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib (Q34332019)

1 August 2017

title

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib (English)

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1 August 2017

Jonathan S Serody

10

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Raquel Sitcheran

object named as

Raquel Sitcheran

Angela Panoskaltsis-Mortari

8

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3

object named as

Angela Panoskaltsis-Mortari

1 reference

1 August 2017

11

Bruce R Blazar

1 reference

1 August 2017

13

William J Murphy

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Lisbeth A. Welniak

2

object named as

Lisbeth A Welniak

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author name string

Kai Sun

1

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1 August 2017

Matthew J O'Shaughnessy

4

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1 August 2017

Haiyan Liu

5

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1 August 2017

Isabel Barao

6

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1 August 2017

William Riordan

7

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1 August 2017

Christian Wysocki

9

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1 August 2017

Thomas J Sayers

12

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1 August 2017

language of work or name

English

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publication date

17 May 2004

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

101

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1 August 2017

issue

21

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1 August 2017

page(s)

8120-8125

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Bortezomib (PS-341): A Novel, First-in-Class Proteasome Inhibitor for the Treatment of Multiple Myeloma and Other Cancers

1 August 2017

cites work

1 reference

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The role of the ubiquitin/proteasome system in cellular responses to radiation

6 July 2018

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Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis

6 July 2018

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Ras regulation of NF-kappa B and apoptosis

6 July 2018

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Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma

6 July 2018

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The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

6 July 2018

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Activation of macrophage cytostatic effector mechanisms during acute graft-versus-host disease: release of intracellular iron and nitric oxide-mediated cytostasis.

6 July 2018

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Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia

6 July 2018

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Proteasome inhibitors: a novel class of potent and effective antitumor agents.

6 July 2018

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Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice

6 July 2018

1 reference

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

6 July 2018

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

6 July 2018

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NF-kappa B: ten years after

6 July 2018

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The NF-kappa B and I kappa B proteins: new discoveries and insights

6 July 2018

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In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment

6 July 2018

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Characterization of target injury of murine acute graft-versus-host disease directed to multiple minor histocompatibility antigens elicited by either CD4+ or CD8+ effector cells

6 July 2018

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The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications

6 July 2018

1 reference

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Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome

21 January 2018

1 reference

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The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.

21 January 2018

1 reference

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Microdialysis: intraoperative and posttraumatic applications in neurosurgery

21 January 2018

1 reference

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Dose and timing of interleukin (IL)-12 and timing and type of total-body irradiation: effects on graft-vs.-host disease inhibition and toxicity of exogenous IL-12 in murine bone marrow transplant recipients

21 January 2018

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12 December 2020

Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice

1 reference

12 December 2020

Proteasome inhibition measurements: clinical application

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12 December 2020

Role of interleukin-12 in acute graft-versus-host disease(1)

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12 December 2020

Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo

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12 December 2020

Inhibition of NF-kappaB-dependent T cell activation abrogates acute allograft rejection

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12 December 2020

Interleukin-12 inhibits murine graft-versus-host disease

1 reference

12 December 2020

Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma

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12 December 2020

The role of granzyme B in murine models of acute graft-versus-host disease and graft rejection

1 reference

12 December 2020

Role of proteasomes in T cell activation and proliferation

1 reference

12 December 2020

The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity

1 reference

12 December 2020

Role of tumor necrosis factor-alpha in graft-versus-host disease and graft-versus-leukemia responses

1 reference

12 December 2020

Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease

1 reference

12 December 2020

Interleukin-1 is a critical effector molecule during cytokine dysregulation in graft versus host disease to minor histocompatibility antigens

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0401563101

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1 August 2017

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1 August 2017

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