Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target (Q34333468)

1 August 2017

title

Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target (English)

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Spermidine/spermine N1-acetyltransferase 1

1 August 2017

main subject

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identical protein binding

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Maria C Bewley

1

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1 August 2017

Vito Graziano

2

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1 August 2017

Jiangsheng Jiang

3

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1 August 2017

Eileen Matz

4

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1 August 2017

F William Studier

5

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1 August 2017

Anthony E Pegg

6

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1 August 2017

Catherine S Coleman

7

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1 August 2017

John M Flanagan

8

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1 August 2017

language of work or name

English

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publication date

2 February 2006

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

103

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1 August 2017

issue

7

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1 August 2017

page(s)

2063-2068

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Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase

1 August 2017

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RGFGIGS is an amino acid sequence required for acetyl coenzyme A binding and activity of human spermidine/spermine N1acetyltransferase

6 July 2018

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Structure and critical residues at the active site of spermidine/spermine-N1-acetyltransferase

6 July 2018

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6 July 2018

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6 July 2018

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12 December 2020

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12 December 2020

Antitumor activity of N,N'-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts

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12 December 2020

Correlations between polyamine analogue-induced increases in spermidine/spermine N1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0511008103

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1 August 2017

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1 August 2017

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