Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects (Q34333515)

1 August 2017

Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects (English)

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1 August 2017

G Sanacora

1

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1 August 2017

M A Smith

2

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1 August 2017

S Pathak

3

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1 August 2017

H-L Su

4

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1 August 2017

P H Boeijinga

5

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1 August 2017

D J McCarthy

6

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1 August 2017

M C Quirk

7

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1 August 2017

language of work or name

English

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publication date

15 October 2013

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1 August 2017

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1 August 2017

19

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1 August 2017

9

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1 August 2017

978-985

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https://scigraph.springernature.com/pub.10.1038/mp.2013.130

1 August 2017

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cites work

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A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression

6 July 2018

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6 July 2018

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Synaptic dysfunction in depression: potential therapeutic targets

6 July 2018

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Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression

6 July 2018

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Ketamine for depression: where do we go from here?

6 July 2018

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Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial

6 July 2018

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¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism

6 July 2018

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The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

6 July 2018

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Differential role of NR2A and NR2B subunits in N-methyl-D-aspartate receptor antagonist-induced aberrant cortical gamma oscillations

6 July 2018

1 reference

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Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders

6 July 2018

1 reference

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NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

6 July 2018

1 reference

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

6 July 2018

1 reference

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Subanesthetic dose of ketamine decreases prefrontal theta cordance in healthy volunteers: implications for antidepressant effect

6 July 2018

1 reference

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The STAR*D trial: revealing the need for better treatments

6 July 2018

1 reference

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NMDA receptor hypofunction leads to generalized and persistent aberrant gamma oscillations independent of hyperlocomotion and the state of consciousness

6 July 2018

1 reference

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Potency, voltage-dependency, agonist concentration-dependency, blocking kinetics and partial untrapping of the uncompetitive N-methyl-D-aspartate (NMDA) channel blocker memantine at human NMDA (GluN1/GluN2A) receptors

6 July 2018

1 reference

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An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder.

6 July 2018

1 reference

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Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4195977

NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons

6 July 2018

1 reference

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Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block.

6 July 2018

1 reference

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The GABA-glutamate connection in schizophrenia: which is the proximate cause?

6 July 2018

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Early changes in prefrontal activity characterize clinical responders to antidepressants

6 July 2018

1 reference

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Differences in degree of trapping of low-affinity uncompetitive N-methyl-D-aspartic acid receptor antagonists with similar kinetics of block.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4195977

Low-affinity NMDA receptor antagonists. The neuroprotective potential of ARL 15896AR.

6 July 2018

1 reference

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Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4195977

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

6 July 2018

1 reference

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The novel anticonvulsant MK-801 binds to the activated state of the N-methyl-D-aspartate receptor in rat brain

6 July 2018

1 reference

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A defined network of fast-spiking interneurons in orbitofrontal cortex: responses to behavioral contingencies and ketamine administration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4195977

STAR*D: revising conventional wisdom.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4195977

Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors.

27 October 2018

1 reference

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Pharmacodynamic effects of acamprosate on markers of cerebral function in alcohol-dependent subjects administered as pretreatment and during alcohol abstinence

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4195977

Structural modifications to an N-methyl-D-aspartate receptor antagonist result in large differences in trapping block

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4195977

Cortical correlates of vigilance regulation and their use in evaluating the effects of treatment

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24126931

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MP.2013.130

1 reference

1 August 2017

1 reference

1 August 2017

1 reference