The role of apoptosis in the pathogenesis of the myelodysplastic syndromes (Q34336402)

1 August 2017

1 reference

title

The role of apoptosis in the pathogenesis of the myelodysplastic syndromes (English)

1 reference

1 August 2017

Parker JE

1

1 reference

1 August 2017

Mufti GJ

series ordinal

2

1 reference

1 August 2017

publication date

1 June 2001

1 reference

International Journal of Hematology

1 August 2017

published in

1 reference

1 August 2017

volume

73

1 reference

1 August 2017

issue

4

1 reference

1 August 2017

page(s)

416-428

1 reference

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF02994003

The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02994003

Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02994003

Bcl-2 expression in acute myeloblastic leukaemia: relationship with autonomous growth and CD34 antigen expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02994003

Autonomous proliferation and bcl-2 expression involving haematopoietic cells in patients with myelodysplastic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02994003

Excessive proliferation matched by excessive apoptosis in myelodysplastic syndromes: the cause-effect relationship

21 January 2018

1 reference

12 December 2020

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1 reference

12 December 2020

Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

1 reference

12 December 2020

Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity

1 reference

12 December 2020

Indication of an involvement of interleukin-1 beta converting enzyme-like protease in intramedullary apoptotic cell death in the bone marrow of patients with myelodysplastic syndromes

1 reference

12 December 2020

BCL-2 immunoreactivity increases with severity of CIN: a study of normal cervical epithelia, CIN, and cervical carcinoma

1 reference

12 December 2020

Apoptosis and its role in the myelodysplastic syndromes: implications for disease natural history and treatment

1 reference

12 December 2020

Inhibition of death receptor signals by cellular FLIP

1 reference

12 December 2020

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

1 reference

12 December 2020

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

12 December 2020

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

1 reference

12 December 2020

Impairment of GM-CSF production in myelodysplastic syndromes

1 reference

12 December 2020

Serum stem cell factor concentration in patients with myelodysplastic syndromes

1 reference

12 December 2020

Is apoptosis a massive process in myelodysplastic syndromes?

1 reference

12 December 2020

Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro

1 reference

12 December 2020

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

1 reference

12 December 2020

Hypothesis: apoptosis may be the mechanism responsible for the premature intramedullary cell death in the myelodysplastic syndrome.

1 reference

12 December 2020

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

12 December 2020

A role for tumour necrosis factor-alpha, Fas and Fas-Ligand in marrow failure associated with myelodysplastic syndrome

1 reference

12 December 2020

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

12 December 2020

Apoptosis in patients with myelodysplastic syndromes: differential involvement of marrow cells in 'good' versus 'poor' prognosis patients and correlation with apoptosis-related genes

1 reference

12 December 2020

Oxidative DNA damage in CD34+ myelodysplastic cells is associated with intracellular redox changes and elevated plasma tumour necrosis factor-alpha concentration

1 reference

12 December 2020

Prognostic value of the combined suicide level of granulocyte progenitors and the labelling index of precursors in preleukemic states and oligoblastic leukemias

1 reference

12 December 2020

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors

1 reference

12 December 2020

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

12 December 2020

Mitochondrial permeability transition is a central coordinating event of apoptosis

1 reference

12 December 2020

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

12 December 2020

Hypermethylation of the p15INK4B gene in myelodysplastic syndromes

1 reference

12 December 2020

Programmed cell death regulation: basic mechanisms and therapeutic opportunities

1 reference

12 December 2020

Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors

1 reference

12 December 2020

Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers

1 reference

12 December 2020

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1 reference

12 December 2020

Spontaneous down-regulation of Fas-associated phosphatase-1 may contribute to excessive apoptosis in myelodysplastic marrows

1 reference

12 December 2020

Fas ligand expression in the bone marrow in myelodysplastic syndromes correlates with FAB subtype and anemia, and predicts survival

1 reference

12 December 2020

Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

1 reference

12 December 2020

High levels of Ca(2+)-independent endonuclease activity capable of producing nucleosomal-size DNA fragmentation in non-adherent marrow mononuclear cells from patients with myelodysplastic syndromes and acute myelogenous leukemia.

1 reference

12 December 2020

Measurement of serum cytokine levels in patients with myelodysplastic syndromes

1 reference

12 December 2020

Mitochondrial release of caspase-2 and -9 during the apoptotic process

1 reference

12 December 2020

In vitro assessment of marrow ‘stem cell’and stromal cell function in aplastic anaemia

1 reference

12 December 2020

Incidence and role of apoptosis in myelodysplastic syndrome: morphological and ultrastructural assessment

1 reference

12 December 2020

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

1 reference

12 December 2020

Molecular thanatopsis: a discourse on the BCL2 family and cell death.

1 reference

12 December 2020

Channel formation by antiapoptotic protein Bcl-2.

1 reference

12 December 2020

Caspases: enemies within

1 reference

12 December 2020

Apoptosis is a Common Histopathological Finding in Myelodysplasia: the Correlate of Ineffective Haematopoiesis.

1 reference

12 December 2020

Mutations in the p53 gene in myelodysplastic syndromes

1 reference

12 December 2020

Mitochondria and apoptosis

1 reference

12 December 2020

Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression

1 reference

12 December 2020

Cell cycle kinetic studies in 68 patients with myelodysplastic syndromes following intravenous iodo- and/or bromodeoxyuridine

1 reference

12 December 2020

Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.

1 reference

12 December 2020

Correlation of tumor necrosis factor alpha (TNF alpha) with high Caspase 3-like activity in myelodysplastic syndromes

1 reference

12 December 2020

Myelodysplastic syndromes: natural history and features of prognostic importance

1 reference

12 December 2020

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

12 December 2020

Low serum levels of tumor necrosis factor and interleukin-1 beta in myelodysplastic syndromes responsive to recombinant erythropoietin

1 reference

12 December 2020

Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes.

1 reference

12 December 2020

Fas/APO-1 (CD95) expression in myelodysplastic syndromes

1 reference

12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

12 December 2020

Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes

1 reference

12 December 2020

Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis

1 reference

12 December 2020

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1 reference

12 December 2020

Fas/Apo-1(CD95) expression and apoptosis in patients with myelodysplastic syndromes

1 reference

12 December 2020

DNA content and cell cycle analysis of bone marrow cells in myelodysplastic syndromes (MDS)

1 reference

12 December 2020

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

1 reference

12 December 2020

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

1 reference

12 December 2020

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

1 reference

12 December 2020

A role for CD95 ligand in preventing graft rejection

1 reference

12 December 2020

'Low-risk' myelodysplastic syndrome is associated with excessive apoptosis and an increased ratio of pro- versus anti-apoptotic bcl-2-related proteins

1 reference

12 December 2020

Bcl-2 and the regulation of programmed cell death

1 reference

12 December 2020

Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: relation to disease progression

1 reference

12 December 2020

Marked apoptosis of human myelomonocytic leukemia cell line P39: significance of cellular differentiation

1 reference

12 December 2020

Ultraviolet B irradiation of human leukaemia HL-60 cells in vitro induces apoptosis

1 reference

12 December 2020

Restoration of impaired cytokine secretion from monocytes of patients with myelodysplastic syndromes after in vivo treatment with GM-CSF or IL-3

1 reference

12 December 2020

Intramedullary apoptosis of hematopoietic cells in myelodysplastic syndrome patients can be massive: apoptotic cells recovered from high-density fraction of bone marrow aspirates

1 reference

12 December 2020

Flow cytometric DNA content in myelodysplastic syndromes

1 reference

12 December 2020

Activity of the caspase-3/CPP32 enzyme is increased in “early stage” myelodysplastic syndromes with excessive apoptosis, but caspase inhibition does not enhance colony formation in vitro

1 reference

12 December 2020

Negative regulators of hemopoiesis and stroma function in patients with myelodysplastic syndrome

1 reference

12 December 2020

Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes

1 reference

12 December 2020

Death and decoy receptors and p53-mediated apoptosis.

1 reference

12 December 2020

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

12 December 2020

Localization of Fas and Fas ligand in bone marrow cells demonstrating myelodysplasia

1 reference

12 December 2020

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1 reference

12 December 2020

The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS.

1 reference

12 December 2020

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

12 December 2020

Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell.

1 reference

12 December 2020

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

12 December 2020

Critical aspects in the analysis of apoptosis and necrosis

1 reference

12 December 2020

Cell adhesion in the stromal regulation of haemopoiesis

1 reference

12 December 2020

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

12 December 2020

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

1 reference

12 December 2020

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

1 reference

12 December 2020

Apoptosis, bcl-2 expression and p53 accumulation in myelodysplastic syndrome, myelodysplastic-syndrome-derived acute myelogenous leukemia and de novo acute myelogenous leukemia

1 reference

12 December 2020

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

12 December 2020

Serum levels of tumour necrosis factor-alpha predict response to recombinant human erythropoietin in patients with myelodysplastic syndrome

1 reference

12 December 2020

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils

1 reference

12 December 2020

The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling

1 reference

12 December 2020

Coregulation of the APO-1 antigen with intercellular adhesion molecule-1 (CD54) in tonsillar B cells and coordinate expression in follicular center B cells and in follicle center and mediastinal B-cell lymphomas.

1 reference

12 December 2020

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

1 reference

12 December 2020

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

1 reference

12 December 2020

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

12 December 2020

1 reference

12 December 2020

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1 reference

12 December 2020

Characterization of two receptors for TRAIL

1 reference

12 December 2020

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

1 reference

12 December 2020

Functional studies of bone marrow haemopoietic and stromal cells in the myelodysplastic syndrome (MDS)

1 reference

12 December 2020

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1 reference

12 December 2020

A novel receptor for Apo2L/TRAIL contains a truncated death domain

1 reference

12 December 2020

Expression and activity of caspases 1 and 3 in myelodysplastic syndromes

1 reference

12 December 2020

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

12 December 2020

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

1 reference

12 December 2020

Apoptotic megakaryocyte dysplasia in the myelodysplastic syndromes.

1 reference

12 December 2020

Bcl-2, Bax and p53 expression in B-CLL in relation to in vitro survival and clinical progression

1 reference

12 December 2020

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

1 reference

12 December 2020

Measurement of apoptosis, proliferation and three cytokines in 46 patients with myelodysplastic syndromes.

1 reference

12 December 2020

Patients with myelodysplastic syndromes benefit from palliative therapy with amifostine, pentoxifylline, and ciprofloxacin with or without dexamethasone

1 reference

12 December 2020

Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia.

1 reference

12 December 2020

Sequential activation of caspase-1 and caspase-3-like proteases during apoptosis in myelodysplastic syndromes

1 reference

12 December 2020

Antiapoptotic bcl-2 and bcl-xL in advanced malignant melanoma

1 reference

12 December 2020

Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death

1 reference

12 December 2020

Caspase-activation and induction of inducible nitric oxide-synthase during TNF alpha-triggered apoptosis

1 reference

12 December 2020

Biologic characteristics of 164 patients with myelodysplastic syndromes

1 reference

12 December 2020

Double identity for proteins of the Bcl-2 family

1 reference

12 December 2020

A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis

1 reference

12 December 2020

Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity

1 reference

12 December 2020

1 reference

12 December 2020

FAP-1: a protein tyrosine phosphatase that associates with Fas

1 reference

12 December 2020

Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL

1 reference

12 December 2020

The Mitochondrial F0F1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells.

1 reference

12 December 2020

Bone marrow stroma from refractory anemia of myelodysplastic syndrome is defective in its ability to support normal CD34-positive cell proliferation and differentiation in vitro

1 reference

12 December 2020

Establishment of stromal cell line from an MDS RA patient which induced an apoptotic change in hematopoietic and leukemic cells in vitro

1 reference

12 December 2020

Altered oncoprotein expression and apoptosis in myelodysplastic syndrome marrow cells.

1 reference

12 December 2020

High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy

1 reference

12 December 2020

bcl-2 expression in myelodysplastic syndromes and its correlation with hematological features, p53 mutations and prognosis

1 reference

12 December 2020

CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10

1 reference

12 December 2020

Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

1 reference

12 December 2020

Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification

1 reference

12 December 2020

p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies

1 reference

12 December 2020

bcl-2 proto-oncogene expression in normal and neoplastic human myeloid cells

1 reference

12 December 2020

Morphological changes and apoptosis in bone marrow from patients with myelodysplastic syndromes treated with granulocyte-CSF and erythropoietin

1 reference

12 December 2020

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

12 December 2020

Apoptosis induced by anticancer drugs

1 reference

12 December 2020

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

12 December 2020

Activation of caspases triggered by cytochrome c in vitro

1 reference

12 December 2020

Hypocellular myelodysplastic syndromes (MDS): new proposals.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02994003

1 reference

Dimensions Publication ID

1 August 2017

1050585720

0 references

1 reference