Molecular pathways: ROS1 fusion proteins in cancer (Q34347504)

1 August 2017

title

Molecular pathways: ROS1 fusion proteins in cancer (English)

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1 August 2017

2

Robert C Doebele

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1 August 2017

Kurtis D Davies

1

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1 August 2017

language of work or name

English

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publication date

29 May 2013

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1 August 2017

published in

Clinical Cancer Research

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1 August 2017

volume

19

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1 August 2017

issue

15

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1 August 2017

page(s)

4040-4045

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Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions

1 August 2017

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6 July 2018

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ROS1 receptor tyrosine kinase, a druggable target, is frequently overexpressed in non-small cell lung carcinomas via genetic and epigenetic mechanisms

6 July 2018

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Analysis of receptor tyrosine kinase ROS1-positive tumors in non-small cell lung cancer: identification of a FIG-ROS1 fusion

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The oncogenic lung cancer fusion kinase CD74-ROS activates a novel invasiveness pathway through E-Syt1 phosphorylation.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The multifaceted roles of the receptor tyrosine kinase ROS in development and cancer

6 July 2018

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6 July 2018

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6 July 2018

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ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice

6 July 2018

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6 July 2018

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6 July 2018

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Oncogenic targeting of an activated tyrosine kinase to the Golgi apparatus in a glioblastoma

6 July 2018

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The role of phosphatidylinositol 3-kinase, rho family GTPases, and STAT3 in Ros-induced cell transformation

6 July 2018

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6 July 2018

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Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation

6 July 2018

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Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

6 July 2018

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The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis

6 July 2018

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Two chimeric receptors of epidermal growth factor receptor and c-Ros that differ in their transmembrane domains have opposite effects on cell growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732549

Characterization of an activated human ros gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732549

Human c-ros-1 gene homologous to the v-ros sequence of UR2 sarcoma virus encodes for a transmembrane receptorlike molecule

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732549

Expression and rearrangement of the ROS1 gene in human glioblastoma cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732549

ROS1-rearranged lung cancer: a clinicopathologic and molecular study of 15 surgical cases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732549

Identification of ROS1 rearrangement in gastric adenocarcinoma

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732549

Effect of dimerization on signal transduction and biological function of oncogenic Ros, insulin, and insulin-like growth factor I receptors.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732549

10.1158/1078-0432.CCR-12-2851

27 October 2018

Identifiers

DOI

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1 August 2017

1 reference

1 August 2017

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