Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model (Q34350044)

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English	Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

spinocerebellar ataxia type 7

1 reference

based on heuristic

inferred from title

4

object named as

Ulo Langel

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author name string

Abiodun Ajayi

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Xin Yu

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Staffan Lindberg

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Ulo Langel

4

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Anna-Lena Ström

5

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

publication date

24 July 2012

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Europe PubMed Central

PubMed publication ID

1 August 2017

BMC Neuroscience

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

86

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Europe PubMed Central

PubMed publication ID

1 August 2017

Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model

1 reference

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6 July 2018

In vitro and in vivo aggregation of a fragment of huntingtin protein directly causes free radical production

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6 July 2018

Mitochondrial dysfunction, metabolic deficits, and increased oxidative stress in Huntington's disease.

1 reference

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Early and late events induced by polyQ-expanded proteins: identification of a common pathogenic property of polYQ-expanded proteins

1 reference

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6 July 2018

Protein oxidative modifications in the ageing brain: consequence for the onset of neurodegenerative disease

1 reference

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6 July 2018

Neurotoxic protein oligomerisation associated with polyglutamine diseases

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Downregulation of NF-kappaB signaling by mutant huntingtin proteins induces oxidative stress and cell death

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Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation

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6 July 2018

Oxidative stress in neurodegeneration and available means of protection.

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6 July 2018

Reconciling the chemistry and biology of reactive oxygen species

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6 July 2018

Oxidative stress and neurotoxicity

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Polyglutamine diseases: emerging concepts in pathogenesis and therapy

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6 July 2018

Proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Huntingtin inclusion bodies are iron-dependent centers of oxidative events.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

A role for both wild-type and expanded ataxin-7 in transcriptional regulation

1 reference

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6 July 2018

Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration

1 reference

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6 July 2018

Glutathione transferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Protein aggregation and neurodegenerative disease

1 reference

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6 July 2018

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes

1 reference

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6 July 2018

Glutathione depletion and oxidative stress

1 reference

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6 July 2018

Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression

1 reference

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6 July 2018

Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

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6 July 2018

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

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6 July 2018

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

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6 July 2018

Oxidative stress, glutamate, and neurodegenerative disorders

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6 July 2018

The olivopontocerebellar atrophies: a review

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6 July 2018

A direct demonstration of the catalytic action of superoxide dismutase through the use of pulse radiolysis.

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6 July 2018

Expression of ataxin-7 in CNS and non-CNS tissue of normal and SCA7 individuals.

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21 January 2018

Molecular Genetics and Biomarkers of Polyglutamine Diseases

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21 January 2018

Oxidative stimuli affect polyglutamine aggregation and cell death in human mutant ataxin-1-expressing cells

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21 January 2018

Human retinoic acid receptor-related orphan receptor alpha1 overexpression protects neurones against oxidative stress-induced apoptosis

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21 January 2018

Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds.

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21 January 2018

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

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21 January 2018

Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria

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21 January 2018

Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III.

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21 January 2018

NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth.

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21 January 2018

Oxidative stress in skin fibroblasts cultures of patients with Huntington's disease.

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21 January 2018

Proteomic and oxidative stress analysis in human brain samples of Huntington disease.

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Oxidative stress in neurodegeneration in dentatorubral-pallidoluysian atrophy

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Expression analysis of ataxin-7 mRNA and protein in human brain: evidence for a widespread distribution and focal protein accumulation

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Expression of human A4V mutant Cu,Zn superoxide dismutase in Schizosaccharomyces pombe: investigations of its toxic properties

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Distribution of ataxin-7 in normal human brain and retina

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10.1186/1471-2202-13-86

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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