Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake (Q34352004)

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English	Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake	scientific article

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scholarly article

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Europe PubMed Central

1 August 2017

Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake (English)

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Europe PubMed Central

1 August 2017

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Gerald I. Shulman

7

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Gerald I Shulman

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Europe PubMed Central

1 August 2017

author name string

Kalyani G Bharadwaj

1

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Europe PubMed Central

1 August 2017

Yaeko Hiyama

2

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Europe PubMed Central

1 August 2017

Yunying Hu

3

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Europe PubMed Central

1 August 2017

Lesley Ann Huggins

4

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Europe PubMed Central

1 August 2017

Rajasekhar Ramakrishnan

5

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Europe PubMed Central

1 August 2017

Nada A Abumrad

6

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Europe PubMed Central

1 August 2017

William S Blaner

8

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Europe PubMed Central

1 August 2017

Ira J Goldberg

9

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Europe PubMed Central

1 August 2017

language of work or name

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publication date

18 September 2010

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Europe PubMed Central

1 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

1 August 2017

285

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Europe PubMed Central

1 August 2017

49

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Europe PubMed Central

1 August 2017

37976-37986

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Europe PubMed Central

1 August 2017

Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators

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VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation.

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Cellular fatty acid uptake: a pathway under construction

1 reference

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Cardiac metabolic compensation to hypertension requires lipoprotein lipase

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Protein-mediated fatty acid uptake: novel insights from in vivo models

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Long-chain fatty acid uptake and FAT/CD36 translocation in heart and skeletal muscle

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Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

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Role of FATP in parenchymal cell fatty acid uptake.

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6 July 2018

Regulation of fatty acid transport by fatty acid translocase/CD36

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Retinol-binding protein-deficient mice: biochemical basis for impaired vision

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6 July 2018

New insights into long-chain fatty acid uptake by heart muscle: a crucial role for fatty acid translocase/CD36

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6 July 2018

Role of CD36 in membrane transport of long-chain fatty acids

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6 July 2018

Fatty acid transport: the roads taken

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6 July 2018

CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism

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6 July 2018

In vivo evidence for both lipolytic and nonlipolytic function of hepatic lipase in the metabolism of HDL.

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6 July 2018

How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?

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Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein

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6 July 2018

Mechanisms of cellular uptake of long chain free fatty acids

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6 July 2018

Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo

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6 July 2018

Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes

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6 July 2018

Increased plasma and renal clearance of an exchangeable pool of apolipoprotein A-I in subjects with low levels of high density lipoprotein cholesterol

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6 July 2018

Reduced lipolysis of large apo E-poor very-low-density lipoprotein subfractions from type IV hypertriglyceridemic subjects in vitro and in vivo.

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6 July 2018

Binding of sulfosuccinimidyl fatty acids to adipocyte membrane proteins: isolation and amino-terminal sequence of an 88-kD protein implicated in transport of long-chain fatty acids

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6 July 2018

Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse

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6 July 2018

Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36

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6 July 2018

CD36 is a receptor for oxidized low density lipoprotein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992231

6 July 2018

Sterol synthesis in vivo in 18 tissues of the squirrel monkey, guinea pig, rabbit, hamster, and rat.

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6 July 2018

Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man.

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Uptake of fatty acids by isolated heart myocytes.

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6 July 2018

Myocardial metabolism of free fatty acids. Studies with 14C-labeled substrates in humans

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Oleate uptake by cardiac myocytes is carrier mediated and involves a 40-kD plasma membrane fatty acid binding protein similar to that in liver, adipose tissue, and gut

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992231

6 July 2018

Fatty acid uptake by isolated rat heart myocytes represents a carrier-mediated transport process.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992231

6 July 2018

Uptake of oleate by isolated rat adipocytes is mediated by a 40-kDa plasma membrane fatty acid binding protein closely related to that in liver and gut.

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6 July 2018

A human 88-kD membrane glycoprotein (CD36) functions in vitro as a receptor for a cytoadherence ligand on Plasmodium falciparum-infected erythrocytes

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6 July 2018

Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion

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Isolation of the thrombospondin membrane receptor

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In vitro remodelling of plasma lipoproteins in whole plasma by lipoprotein lipase in primary and secondary hypertriglyceridaemia

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6 July 2018

Role of lipoprotein lipase in the regulation of high density lipoprotein apolipoprotein metabolism. Studies in normal and lipoprotein lipase-inhibited monkeys

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6 July 2018

Metabolism of cholesterol-rich chylomicroms. Mechanism of binding and uptake of cholesteryl esters by the vascular bed of the perfused rat heart

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6 July 2018

Uncoupler- and hypoxia-induced damage in the working rat heart and its treatment. I. Observations with uncouplers of oxidative phosphorylation.

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Transport of long-chain native fatty acids across human erythrocyte ghost membranes

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21 January 2018

A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism.

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21 January 2018

Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction.

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21 January 2018

Routes of FA delivery to cardiac muscle: modulation of lipoprotein lipolysis alters uptake of TG-derived FA.

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21 January 2018

Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression

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21 January 2018

CD36 Deficiency Rescues Lipotoxic Cardiomyopathy

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Utilization of triacylglycerol-rich lipoproteins by the working rat heart: routes of uptake and metabolic fates

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Dose-Dependent Acceleration of High-Density Lipoprotein Catabolism by Endothelial Lipase

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Tamoxifen is a potent inhibitor of cholesterol esterification and prevents the formation of foam cells.

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Acute lipoprotein lipase deletion in adult mice leads to dyslipidemia and cardiac dysfunction

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Differential binding of triglyceride-rich lipoproteins to lipoprotein lipase.

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27 October 2018

'Albumin-receptor' uptake kinetics do not require an intact lobular architecture and are not specific for albumin

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12 December 2020

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Detection and characterization of the heterozygote state for lipoprotein lipase deficiency

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https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

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Fatty acid uptake by human hepatoma cell lines represents a carrier-mediated uptake process

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https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

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Characteristics of oleate binding to liver plasma membranes and its uptake by isolated hepatocytes

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https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid flip-flop in phospholipid bilayers is extremely fast

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https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

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Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both

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https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoprotein lipase activity and mRNA levels in bovine tissues

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https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

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Lipoprotein lipase-mediated selective uptake from low density lipoprotein requires cell surface proteoglycans and is independent of scavenger receptor class B type 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice

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https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid transport: the diffusion mechanism in model and biological membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

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Uptake and metabolism of fatty acids by dispersed adult rat heart myocytes. I. Kinetics of homologous fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI

1 reference

https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20852327

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20852327

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Identifiers

10.1074/JBC.M110.174458

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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